Page 130 - 《中国药房》2025年18期
P. 130
[22] PAN S,JIANG S S,LI R,et al. Hong Guo Ginseng Guo [32] ABOISMAIEL M G,AMIN M N,EISSA L A. Renopro‐
(HGGG)protects against kidney injury in diabetic ne‐ tective effect of a novel combination of 6-gingerol and
phropathy by inhibiting NLRP3 inflammasome and regu‐ metformin in high-fat diet/streptozotocin-induced diabetic
lating intestinal flora[J]. Phytomedicine,2024,132: nephropathy in rats via targeting miRNA-146a,miRNA-
155861. 223,TLR4/TRAF6/NLRP3 inflammasome pathway and
[23] REN C X,ZHOU X W,BAO X W,et al. Dioscorea zingi‐ HIF-1α[J]. Biol Res,2024,57(1):47.
berensis ameliorates diabetic nephropathy by inhibiting [33] CHENG Y,LU Z J,MAO T Y,et al. Magnoflorine ame‐
NLRP3 inflammasome and curbing the expression of liorates chronic kidney disease in high-fat and high-
p66Shc in high-fat diet/streptozotocin-induced diabetic fructose-fed mice by promoting Parkin/PINK1-dependent
mice[J]. J Pharm Pharmacol,2021,73(9):1218-1229. mitophagy to inhibit NLRP3/caspase-1-mediated pyropto‐
[24] ZHANG C,XIONG Y K,LUO Y X,et al. Morroniside sis[J]. J Agric Food Chem,2024,72(22):12775-12787.
ameliorates high-fat and high-fructose-driven chronic kid‐ [34] TAN E X,GAO Z H,WANG Q,et al. Berberine amelio‐
ney disease by motivating AMPK-TFEB signal activation rates renal interstitial inflammation and fibrosis in mice
to accelerate lipophagy and inhibiting inflammatory re‐ with unilateral ureteral obstruction[J]. Basic Clin Pharma‐
sponse[J]. J Agric Food Chem,2025,73(10):6158-6172. col Toxicol,2023,133(6):757-769.
[25] XIE J,MA X,LI X Y,et al. Panax notoginseng saponins [35] HUNG C C,CHEN K H,HSU H H,et al. Noscapine alle‐
alleviate LPS-induced fibrosis of HK-2 cells by inhibiting viates unilateral ureteral obstruction-induced inflamma‐
the activation of NLRP3 inflammasome and pyroptosis[J]. tion and fibrosis by regulating the TGF- β1/Smads signa-
Curr Pharm Biotechnol,2023:CPB-EPUB-130976. ling pathways[J]. Biochim Biophys Acta Mol Cell Res,
[26] YANG G H,YANG W,JIANG H R,et al. Hederagenin in‐ 2024,1871(1):119594.
hibits high glucose-induced fibrosis in human renal cells [36] WANG M Z,WANG J,CAO D W,et al. Fucoidan alle-
by suppression of NLRP3 inflammasome activation viates renal fibrosis in diabetic kidney disease via inhibition
through reducing cathepsin B expression[J]. Chem Biol of NLRP3 inflammasome-mediated podocyte pyroptosis
Drug Des,2023,102(6):1409-1420. [J]. Front Pharmacol,2022,13:790937.
[27] ZHU X G,SHI J,LI H C. Liquiritigenin attenuates high [37] LIAO L,TAO P Y,XU Q M,et al. Bushen huoxue for‐
glucose-induced mesangial matrix accumulation,oxida‐ mula protects against renal fibrosis and pyroptosis in
tive stress,and inflammation by suppression of the NF-κB chronic kidney disease by inhibiting ROS/NLRP3-medi-
and NLRP3 inflammasome pathways[J]. Biomed Pharma‐ ated inflammasome activation[J]. Ren Fail,2024,46(1):
cother,2018,106:976-982. 2354444.
[28] YOSRI H,EL-KASHEF D H,EL-SHERBINY M,et al. [38] JIA Q,ZHANG X Y,HAO G M,et al. Tongluo yishen de‐
Calycosin modulates NLRP3 and TXNIP-mediated pyro- coction ameliorates renal fibrosis via NLRP3-mediated py‐
ptotic signaling and attenuates diabetic nephropathy pro‐ roptosis in vivo and in vitro[J]. Front Pharmacol,2022,13:
gression in diabetic rats;an insight[J]. Biomed Pharmaco‐ 936853.
ther,2022,155:113758. [39] ZHU Y Y,HUANG G S,YANG Y,et al. Chinese herbal
[29] RAM C,GAIROLA S,VERMA S,et al. Biochanin a ame‐ medicine Suyin detoxification granule inhibits pyroptosis
liorates nephropathy in high-fat diet/streptozotocin- and epithelial-mesenchymal transition by downregulating
induced diabetic rats:effects on NF-κB/NLRP3 axis,py‐ MAVS/NLRP3 to alleviate renal injury[J]. J Inflamm Res,
roptosis,and fibrosis[J]. Antioxidants(Basel),2023,12 2021,14:6601-6618.
(5):1052. [40] ZHOU J B,WANG C X,ZHANG X M,et al. Shizhifang
[30] HUNG T W,HSIEH Y H,LEE H L,et al. Renoprotective ameliorates pyroptosis of renal tubular epithelial cells in
effect of rosmarinic acid by inhibition of indoxyl sulfate- hyperuricemia through inhibiting NLRP3 inflammasome
induced renal interstitial fibrosis via the NLRP3 inflamma‐ [J]. J Ethnopharmacol,2023,317:116777.
some signaling[J]. Int Immunopharmacol,2024,135: [41] LIN X H,ZOU X J,HU B F,et al. Bi Xie Fen Qing Yin
112314. decoction alleviates potassium oxonate and adenine-
[31] LU M M,LI H,LIU W L,et al. Curcumin attenuates renal induced hyperuricemic nephropathy in mice by modula-
interstitial fibrosis by regulating autophagy and retaining ting gut microbiota and intestinal metabolites[J]. Biomed
mitochondrial function in unilateral ureteral obstruction Pharmacother,2024,170:116022.
rats[J]. Basic Clin Pharmacol Toxicol,2021,128(4): (收稿日期:2025-04-16 修回日期:2025-08-19)
594-604. (编辑:胡晓霖)
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