Page 24 - 《中国药房》2025年11期
P. 24

江苏省三级儿童医院药品配备使用情况分析
                                                                              Δ


                          #
                *
          杜雯雯 ,徐 伟(中国药科大学国际医药商学院,南京 211198)
          中图分类号  R95      文献标志码  A      文章编号  1001-0408(2025)11-1306-05
          DOI  10.6039/j.issn.1001-0408.2025.11.03


          摘   要  目的  为有关部门完善儿童医院药品配备、进一步落实儿童合理用药临床管理工作提供参考。方法  利用2012-2023年
          江苏省4家样本三级甲等儿童医院的药品采购数据,围绕医院配备使用药品数量、医院用药集中度、配备使用国家基本药物以及
          儿童临床诊疗指南推荐用药情况、临床用药规范性,对儿童医院药品配备使用情况进行梳理与分析。结果  4 家样本儿童医院
          2023年临床配备使用的药品按品种计有922种、按品规计有1 401个,显著低于当前已上市的儿童药品总数;各医院间用药集中度
          不高,仅1家医院配备使用的药品品种数、药品品规数占比分别在40%、50%左右。现阶段,样本儿童医院配备使用的药品中,国
          家基本药物占比基本维持在30%~40%,儿童可以安全并有效使用的药品占比约为60%,此外40%左右的儿童临床诊疗指南推荐
          用药品种也已用于临床治疗;但目前仍有30%~40%的药品为医生经验用药,儿童禁忌用药和非儿童人群用药现象依旧存在。结论
          我国儿童临床用药数量虽然有限但医院整体用药选择存在较大差异,临床用药的科学性、合理性和规范性也有待进一步加强。
          关键词  儿童用药;药品配备;江苏省;三级甲等儿童医院;药品采购数据;基本药物;合理用药


          Analysis of the drug inventory and use data from tertiary-level children’s hospitals in Jiangsu province
          DU Wenwen,XU Wei(School  of  International  Pharmaceutical  Business,  China  Pharmaceutical  University,
          Nanjing 211198, China)

          ABSTRACT    OBJECTIVE  To  provide  reference  for  relevant  departments  to  improve  the  drug  provision  in  children’s  hospitals
          and  further  implement  clinical  management  practices  for  rational  drug  use  in  pediatric  patients.  METHODS  According  to  the  drug
          purchasing  statistics  of  four  sample  class  A  tertiary  children’s  hospitals  in  Jiangsu  province  from  2012  to  2023,  this  study
          systematically  reviewed  and  analyzed  the  drug  provision  and  utilization  in  children’s  hospitals,  including  the  number  of
          pharmaceuticals  procured  and  used  in  hospitals,  the  concentration  of  drug  usage  among  different  hospitals,  the  situation  of  drugs
          recommended  by  the  National  Essential  Medicine  List  and  children’s  clinical  diagnosis  and  treatment  guidelines,  and  the
          standardization  of  clinical  medication.  RESULTS  In  2023,  the  number  of  commonly  used  drugs  in  4  tertiary  children’s  hospitals
          was  922  varieties  and  1  401  specifications,  which  was  significantly  lower  than  the  total  number  of  currently  marketed  children’s
          drugs. However, the concentration of drug usage among different hospitals was not high, with the proportion of drugs supplied and
          used  in  only  one  hospital  accounting  for  approximately  40%  and  50%  respectively  in  terms  of  drug  variety  and  specification.  At
          present, among the drugs procured and used in sample children’s hospitals, the proportion of national essential medicines basically
          maintained  between  30%  and  40%,  while  drugs  which  could  be  safely  and  effectively  used  for  children  was  about  60%.  In
          addition,  around  40%  of  the  drug  varieties  recommended  in  pediatric  clinical  practice  guidelines  had  also  been  applied  in  clinical
          treatment.  Nevertheless,  about  30%  to  40%  of  prescription  behavior  was  dependent  on  doctors’  personal  experience  and  the
          phenomena  of  drugs  prohibited  and  unsuitable  use  for  children  still  existed.  CONCLUSIONS  Although  the  number  of  clinical
          medications  for  children  in  China  is  limited,  there  are  significant  differences  in  the  overall  medication  choices  made  by  hospitals.
          The scientific, rational and standardized use of clinical medications also needs to be further strengthened.
          KEYWORDS     drug  use  for  children;  drug  provision;  Jiangsu  province;  class  A  tertiary  children’s  hospitals;  drug  purchasing
          statistics; essential medicines; rational use of drugs


             《2020 年中国儿童人口状况:事实和数据》显示,我                       国 0~17 岁儿童人数约占全国总人口的 21.1%,是社会
                                                              重点关注的群体之一 。受儿童个体间差异较大、对药
                                                                                [1]
              Δ 基金项目 江苏省卫生健康发展研究中心2022年度开放课题面
          上项目(No.JSHD2022018)                                 物的耐受性和反应不同于成人等因素的影响,临床上对
             *第一作者 博士。研究方向:医疗保险与药物政策。E-mail:
                                                              儿童药品的使用和选择相较于成人应更加谨慎和严
          duwenwenznj@163.com
                                                              格 [2―3] 。为此,我国各部门相继出台了多个与儿童临床
              # 通信作者 教授,博士生导师。研究方向:医疗保险与药物政策。
          E-mail:xu2005wei@126.com                            用药管理相关的文件,如《关于保障儿童用药的若干意


          · 1306 ·    China Pharmacy  2025 Vol. 36  No. 11                            中国药房  2025年第36卷第11期
   19   20   21   22   23   24   25   26   27   28   29