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江苏省三级儿童医院药品配备使用情况分析
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杜雯雯 ,徐 伟(中国药科大学国际医药商学院,南京 211198)
中图分类号 R95 文献标志码 A 文章编号 1001-0408(2025)11-1306-05
DOI 10.6039/j.issn.1001-0408.2025.11.03
摘 要 目的 为有关部门完善儿童医院药品配备、进一步落实儿童合理用药临床管理工作提供参考。方法 利用2012-2023年
江苏省4家样本三级甲等儿童医院的药品采购数据,围绕医院配备使用药品数量、医院用药集中度、配备使用国家基本药物以及
儿童临床诊疗指南推荐用药情况、临床用药规范性,对儿童医院药品配备使用情况进行梳理与分析。结果 4 家样本儿童医院
2023年临床配备使用的药品按品种计有922种、按品规计有1 401个,显著低于当前已上市的儿童药品总数;各医院间用药集中度
不高,仅1家医院配备使用的药品品种数、药品品规数占比分别在40%、50%左右。现阶段,样本儿童医院配备使用的药品中,国
家基本药物占比基本维持在30%~40%,儿童可以安全并有效使用的药品占比约为60%,此外40%左右的儿童临床诊疗指南推荐
用药品种也已用于临床治疗;但目前仍有30%~40%的药品为医生经验用药,儿童禁忌用药和非儿童人群用药现象依旧存在。结论
我国儿童临床用药数量虽然有限但医院整体用药选择存在较大差异,临床用药的科学性、合理性和规范性也有待进一步加强。
关键词 儿童用药;药品配备;江苏省;三级甲等儿童医院;药品采购数据;基本药物;合理用药
Analysis of the drug inventory and use data from tertiary-level children’s hospitals in Jiangsu province
DU Wenwen,XU Wei(School of International Pharmaceutical Business, China Pharmaceutical University,
Nanjing 211198, China)
ABSTRACT OBJECTIVE To provide reference for relevant departments to improve the drug provision in children’s hospitals
and further implement clinical management practices for rational drug use in pediatric patients. METHODS According to the drug
purchasing statistics of four sample class A tertiary children’s hospitals in Jiangsu province from 2012 to 2023, this study
systematically reviewed and analyzed the drug provision and utilization in children’s hospitals, including the number of
pharmaceuticals procured and used in hospitals, the concentration of drug usage among different hospitals, the situation of drugs
recommended by the National Essential Medicine List and children’s clinical diagnosis and treatment guidelines, and the
standardization of clinical medication. RESULTS In 2023, the number of commonly used drugs in 4 tertiary children’s hospitals
was 922 varieties and 1 401 specifications, which was significantly lower than the total number of currently marketed children’s
drugs. However, the concentration of drug usage among different hospitals was not high, with the proportion of drugs supplied and
used in only one hospital accounting for approximately 40% and 50% respectively in terms of drug variety and specification. At
present, among the drugs procured and used in sample children’s hospitals, the proportion of national essential medicines basically
maintained between 30% and 40%, while drugs which could be safely and effectively used for children was about 60%. In
addition, around 40% of the drug varieties recommended in pediatric clinical practice guidelines had also been applied in clinical
treatment. Nevertheless, about 30% to 40% of prescription behavior was dependent on doctors’ personal experience and the
phenomena of drugs prohibited and unsuitable use for children still existed. CONCLUSIONS Although the number of clinical
medications for children in China is limited, there are significant differences in the overall medication choices made by hospitals.
The scientific, rational and standardized use of clinical medications also needs to be further strengthened.
KEYWORDS drug use for children; drug provision; Jiangsu province; class A tertiary children’s hospitals; drug purchasing
statistics; essential medicines; rational use of drugs
《2020 年中国儿童人口状况:事实和数据》显示,我 国 0~17 岁儿童人数约占全国总人口的 21.1%,是社会
重点关注的群体之一 。受儿童个体间差异较大、对药
[1]
Δ 基金项目 江苏省卫生健康发展研究中心2022年度开放课题面
上项目(No.JSHD2022018) 物的耐受性和反应不同于成人等因素的影响,临床上对
*第一作者 博士。研究方向:医疗保险与药物政策。E-mail:
儿童药品的使用和选择相较于成人应更加谨慎和严
duwenwenznj@163.com
格 [2―3] 。为此,我国各部门相继出台了多个与儿童临床
# 通信作者 教授,博士生导师。研究方向:医疗保险与药物政策。
E-mail:xu2005wei@126.com 用药管理相关的文件,如《关于保障儿童用药的若干意
· 1306 · China Pharmacy 2025 Vol. 36 No. 11 中国药房 2025年第36卷第11期