Page 123 - 《中国药房》2024年22期
P. 123

[ 7 ]  ROSENBERG J E,PARK S H,KOZLOV V,et al. Dur‐      tive,open-label,randomized,phase Ⅲ study of two dose-
              valumab plus olaparib in previously untreated,platinumi-  dense regimens MVAC versus gemcitabine/cisplatin in pa‐
              neligible  patients  with  metastatic  urothelial  carcinoma:a   tients  with  inoperable,metastatic  or  relapsed  urothelial
              multicenter,randomized,phase  Ⅱ  trial(BAYOU)[J].  J   cancer:a  Hellenic  Cooperative  Oncology  Group  study
              Clin Oncol,2023,41(1):43-53.                       (HE 16/03)[J]. Ann Oncol,2013,24(4):1011-1017.
          [ 8 ]  O’DONNELL P H,MILOWSKY M I,PETRYLAK D P,    [15]  PFISTER C,GRAVIS G,FLECHON A,et al. Periopera‐
              et al. Enfortumab vedotin with or without pembrolizumab   tive  dose-dense  methotrexate,vinblastine,doxorubicin,
              in  cisplatin-ineligible  patients  with  previously  untreated   and cisplatin in muscle-invasive bladder cancer(VESPER):
              locally advanced or metastatic urothelial cancer[J]. J Clin   survival endpoints at 5 years in an open-label,randomised,
              Oncol,2023,41(25):4107-4117.                        phase 3 study[J]. Lancet Oncol,2024,25(2):255-264.
          [ 9 ]  VAN DER HEIJDEN M S,SONPAVDE G,POWLES T,    [16]  METRANGOLO V,ENGELHOLM  L  H. Antibody-drug
              et  al.  Nivolumab  plus  gemcitabine-cisplatin  in  advanced   conjugates:the  dynamic  evolution  from  conventional  to
              urothelial carcinoma[J]. N Engl J Med,2023,389(19):  next-generation  constructs[J].  Cancers(Basel),2024,16
              1778-1789.                                         (2):447.
          [10]  CULINE S,FLÉCHON A,GRAVIS G,et al. Dose-dense   [17]  BARDIA A,MAYER  I A,VAHDAT  L  T,et  al.  Sacitu‐
              methotrexate,vinblastine,doxorubicin,and cisplatin with   zumab  govitecan-hziy  in  refractory  metastatic  triple-
              or without panitumumab in patients with advanced urothe‐  negative breast cancer[J]. N Engl J Med,2019,380(8):
              lial  carcinoma:multicenter,randomized,French  Unican‐  741-751.
              cer  GETUG/AFU  19  study[J].  Clin  Genitourin  Cancer,  [18]  PENG Z,LIU T S,WEI J,et al. Efficacy and safety of a
              2021,19(4):e216-e222.                               novel  anti-HER2  therapeutic  antibody  RC48  in  patients
          [11]  POWLES T,CSÖSZI T,ÖZGÜROĞLU M,et al. Pembro‐      with  HER2-overexpressing,locally  advanced  or  meta‐
              lizumab alone or combined with chemotherapy versus che‐  static gastric or gastroesophageal junction cancer:a single-
              motherapy as first-line therapy for advanced urothelial car‐  arm phase Ⅱ study[J]. Cancer Commun,2021,41(11):
              cinoma(KEYNOTE-361):a  randomised,open-label,       1173-1182.
              phase 3 trial[J]. Lancet Oncol,2021,22(7):931-945.  [19]  TAGAWA  S  T,BALAR  A  V,PETRYLAK  D  P,et  al.
          [12]  POWLES T B,PEREZ VALDERRAMA B,GUPTA S,et          TROPHY-U-01:a  phase  Ⅱ  open-label  study  of  sacitu‐
              al.  LBA6  EV-302/KEYNOTE-A39:open-label,rando-     zumab govitecan in patients with metastatic urothelial car‐
              mized phase Ⅲ study of enfortumab vedotin in combination   cinoma  progressing  after  platinum-based  chemotherapy
              with  pembrolizumab(EV+P)vs.  chemotherapy(Chemo)   and checkpoint inhibitors[J]. J Clin Oncol,2021,39(22):
              in previously untreated locally advanced metastatic urothe‐  2474-2485.
              lial carcinoma(LA/mUC)[J]. Ann Oncol,2023,34:S1340.  [20]  SHENG  X  N,WANG  L,HE  Z  S,et  al.  Efficacy  and
          [13]  POWLES T,VAN DER HEIJDEN M S,CASTELLANO           safety of disitamab vedotin in patients with human epider‐
              D,et al. Durvalumab alone and durvalumab plus tremeli-  mal growth factor receptor 2-positive locally advanced or
              mumab  versus  chemotherapy  in  previously  untreated  pa‐  metastatic  urothelial  carcinoma:a  combined  analysis  of
              tients  with  unresectable,locally  advanced  or  metastatic   two  phase  Ⅱ  clinical  trials[J].  J  Clin  Oncol,2024,42
              urothelial  carcinoma(DANUBE):a  randomised,open-  (12):1391-1402.
              label,multicentre,phase 3 trial[J]. Lancet Oncol,2020,21      (收稿日期:2024-03-19  修回日期:2024-07-28)
              (12):1574-1588.                                                                     (编辑:刘明伟)
          [14]  BAMIAS A,DAFNI U,KARADIMOU A,et al. Prospec‐
















          中国药房  2024年第35卷第22期                                              China Pharmacy  2024 Vol. 35  No. 22    · 2821 ·
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