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本研究选择各样品响应值较高并具代表性的次黄嘌呤、                           [ 8 ]  石琨群,王珏,刘欢欢,等 . 半夏及其炮制品 7 种主要核
          尿苷、腺嘌呤、鸟苷这4种核苷类成分进行含量测定。研                               苷类成分差异性分析[J]. 中国医院药学杂志,2023,43
          究发现,半夏炮制后核苷类成分均有不同程度降低                     [8―9] 。     (11):1232-1238.
          本实验也得出姜半夏经竹沥炮制后,4 种核苷类成分含                               SHI K Q,WANG J,LIU H H,et al. Differential analysis
          量均有所减少,与文献[8―9]具有相同的结论。这可能                              of 7 main nucleoside components in Pinellia ternata and
          是由于姜半夏用竹沥拌匀后,浸润 1 h 使之均匀吸尽的                             its  processed  products[J].  Chin  J  Hosp  Pharm,2023,43
                                                                 (11):1232-1238.
          过程中发生了成分的相互作用而导致核苷类成分含量
                                                             [ 9 ]  李辰荃,郭朝晖,靳婉君,等 . 炮制前后半夏多种核苷类
          下降。                                                     成分变化研究[J]. 中药材,2023,46(7):1664-1668.
              综上所述,本研究建立的方法操作简便、重复性好,                             LI C Q,GUO Z H,JIN W J,et al. Study on the changes of
          可用于姜半夏及竹沥半夏的定性、定量分析;竹沥炮制                                various nucleoside components in Pinellia ternata before
          姜半夏后4种核苷类成分的平均含量降低。本研究结果                                and after processing[J]. J Chin Med Mater,2023,46(7):
          为竹沥半夏质量控制提供了一定的参考。                                      1664-1668.
          参考文献                                               [10]  陈卫,张超,孙磊,等 . 基于核苷类成分利用指纹图谱结
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          中国药房  2024年第35卷第21期                                              China Pharmacy  2024 Vol. 35  No. 21    · 2595 ·
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