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本研究选择各样品响应值较高并具代表性的次黄嘌呤、 [ 8 ] 石琨群,王珏,刘欢欢,等 . 半夏及其炮制品 7 种主要核
尿苷、腺嘌呤、鸟苷这4种核苷类成分进行含量测定。研 苷类成分差异性分析[J]. 中国医院药学杂志,2023,43
究发现,半夏炮制后核苷类成分均有不同程度降低 [8―9] 。 (11):1232-1238.
本实验也得出姜半夏经竹沥炮制后,4 种核苷类成分含 SHI K Q,WANG J,LIU H H,et al. Differential analysis
量均有所减少,与文献[8―9]具有相同的结论。这可能 of 7 main nucleoside components in Pinellia ternata and
是由于姜半夏用竹沥拌匀后,浸润 1 h 使之均匀吸尽的 its processed products[J]. Chin J Hosp Pharm,2023,43
(11):1232-1238.
过程中发生了成分的相互作用而导致核苷类成分含量
[ 9 ] 李辰荃,郭朝晖,靳婉君,等 . 炮制前后半夏多种核苷类
下降。 成分变化研究[J]. 中药材,2023,46(7):1664-1668.
综上所述,本研究建立的方法操作简便、重复性好, LI C Q,GUO Z H,JIN W J,et al. Study on the changes of
可用于姜半夏及竹沥半夏的定性、定量分析;竹沥炮制 various nucleoside components in Pinellia ternata before
姜半夏后4种核苷类成分的平均含量降低。本研究结果 and after processing[J]. J Chin Med Mater,2023,46(7):
为竹沥半夏质量控制提供了一定的参考。 1664-1668.
参考文献 [10] 陈卫,张超,孙磊,等 . 基于核苷类成分利用指纹图谱结
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中国药房 2024年第35卷第21期 China Pharmacy 2024 Vol. 35 No. 21 · 2595 ·