Page 96 - 《中国药房》2023年18期
P. 96
in patients with muscle-invasive bladder cancer[J]. J Clin approach to muscle-invasive urothelial bladder cancer
Oncol,2021,39(28):3140-3148. (MIBC) patients(pts) prospectively selected by an inter‐
[22] FUNT S A,LATTANZI M,WHITING K,et al. Neoadju‐ feron(INF)-gamma immune signature[J]. J Clin Oncol,
vant atezolizumab with gemcitabine and cisplatin in 2020,38(15_suppl):5012.
patients with muscle-invasive bladder cancer:a multi‐ [32] THIBAULT C,ELAIDI R,VANO Y A,et al. Open-label
center,single-arm,phase Ⅱ trial[J]. J Clin Oncol,2022, phase Ⅱ to evaluate the efficacy of neoadjuvant dose-
40(12):1312-1322. dense MVAC in combination with durvalumab and treme‐
[23] ZHANG R Y,ZANG J Y,XIE F,et al. Longitudinal limumab in muscle-invasive urothelial carcinoma:NEMIO
personalized urinary tumor DNA analysis in muscle- [J]. Bull Cancer,2020,107(5S):eS8-eS15.
invasive bladder cancer from the neoadjuvant immuno‐ [33] LIN T X,LI K W,FAN J H,et al. Interim results from a
therapy trial RJBLC-I2N003[J]. J Clin Oncol,2022,40 multicenter clinical study of tislelizumab combined with
(6_suppl):552. gemcitabine and cisplatin as neoadjuvant therapy for
[24] NATESAN D V,ZHANG L,OH D Y,et al. Updated patients with cT2-T4aN0M0 MIBC[J]. J Clin Oncol,
results of phase Ⅱ trial using escalating doses of neoadju‐ 2022,40(16_suppl):4580.
vant atezolizumab for cisplatin-ineligible patients with [34] VAN DORP J,SUELMANN B B M,MEHRA N,et al.
nonmetastatic urothelial cancer(NCT02451423)[J]. J Clin LBA31 High- vs low-dose pre-operative ipilimumab and
Oncol,2021,39(15_suppl):e16510. nivolumab in locoregionally advanced urothelial cancer
[25] WEI X X,ALEXANDER MCGREGOR B,LEE R J,et (NABUCCO cohort 2)[J]. Ann Oncol,2021,32:S1305-
al. Durvalumab as neoadjuvant therapy for muscle-invasive S1306.
bladder cancer:preliminary results from the Bladder Cancer [35] NECCHI A,MARTINI A,RAGGI D,et al. A feasibility
Signal Seeking Trial(BLASST)-2[J]. J Clin Oncol,2020, study of preoperative pembrolizumab before radical
38(6_suppl):507. nephroureterectomy in patients with high-risk,upper tract
[26] GOUBET A G,ALVES COSTA SILVA C,LORDELLO urothelial carcinoma:pure-02[J]. Urol Oncol,2022,40
DE MELO L,et al. Bacteria-specific CXCL13-producing (1):10.e1-10.e6.
follicular helper T cells are putative prognostic markers to [36] KAIMAKLIOTIS H Z,ADRA N,KELLY W K,et al.
neoadjuvant PD-1 blockade in muscle-invasive urothelial Phase Ⅱ neoadjuvant(N-) gemcitabine(G) and pembroli‐
carcinoma[J]. J Clin Oncol,2022,40(6_suppl):535. zumab (P) for locally advanced urothelial cancer
[27] GUERCIO B J,PIETZAK E J,BROWN S,et al. Neoadju‐ (LAUC):interim results from the cisplatin(C)-ineligible
vant nivolumab (N) +/- ipilimumab (I) in cisplatin- cohort of GU14-188[J]. J Clin Oncol,2020,38(15_
ineligible patients(pts)with muscle-invasive bladder can‐ suppl):5019.
cer(MIBC)[J]. J Clin Oncol,2022,40(6_suppl):498. [37] LOWE M C,KUDCHADKAR R R. Neoadjuvant therapy
[28] GRIVAS P,YIN J,KOSHKIN V S,et al. PrE0807:A for melanoma[J]. Surg Oncol Clin N Am,2020,29(3):
phase Ⅰb feasibility trial of neoadjuvant nivolumab(N) 445-53.
without or with lirilumab(L) in cisplatin-ineligible [38] YIN Z,YU M,MA T T,et al. Mechanisms underlying
patients(pts)with muscle-invasive bladder cancer(MIBC) low-clinical responses to PD-1/PD-L1 blocking antibodies
[J]. J Clin Oncol,2021,39(15_suppl):4518. in immunotherapy of cancer:a key role of exosomal
[29] KIM H,KIM R,HONG J,et al. A prospective phase Ⅱ PD-L1[J]. J Immunother Cancer,2021,9(1):e001698.
trial of neoadjuvant nivolumab plus gemcitabine/cisplatin [39] YI M,ZHENG X,NIU M,et al. Combination strategies
chemotherapy in muscle-invasive urothelial carcinoma of with PD-1/PD-L1 blockade:current advances and future
bladder[J]. J Clin Oncol,2022,40(6_suppl):494. directions [J]. Mol Cancer,2022,21(1):28.
[30] XING N,HAN S,JIANG J,et al. 703P Camrelizumab in [40] BOUTROS C,TARHINI A,ROUTIER E,et al. Safety
combination with gemcitabine plus cisplatin as neoadju‐ profiles of anti-CTLA-4 and anti-PD-1 antibodies alone
vant therapy for muscle-invasive bladder cancer[J]. Ann and in combination[J]. Nat Rev Clin Oncol,2016,13(8):
Oncol,2021,32:S714. 473-486.
[31] GRANDE E,GUERRERO F,PUENTE J,et al. Dutreneo (收稿日期:2023-02-08 修回日期:2023-08-06)
trial:a randomized phase Ⅱ trial of durvalumab and (编辑:陈 宏)
tremelimumab versus chemotherapy as a neoadjuvant
· 2262 · China Pharmacy 2023 Vol. 34 No. 18 中国药房 2023年第34卷第18期