Page 102 - 《中国药房》2026年5期
P. 102
应方面更具有优势,而鼓室内注射可能更适合听力损失 (4):811-821.
程度较重的患者,这为突聋个体化治疗提供了新选择。 [10] CHEW S C,MD DAUD M K. The efficacy of intratym‐
未来应致力于构建基于病理分型、损伤程度和临床特征 panic steroid injection for the treatment of idiopathic sud‐
的精准治疗体系,最终改善患者听力预后和生活质量。 den sensorineural hearing loss[J]. Med J Malaysia,2020,
本研究亦存在一定的局限性:作为单中心回顾性研究, 75(1):74-77.
[11] CHRYSOULI K,KOLLIA P,PAPANIKOLAOU V,et al.
样本量相对有限,且部分亚组病例数偏少;同时,本研究
The effectiveness of intratympanic steroid injection in
主要评价的是短期疗效,未能获得统一时间点的长期随
addition to systemic corticosteroids in the treatment of
访数据,这些均会给研究结果带来一定的偏倚。因此,
idiopathic sudden sensorineural hearing loss[J]. Am J
本文所得结论仍需在更大样本的前瞻性研究中进一步
Otolaryngol,2023,44(4):103872.
验证。
[12] 中华耳鼻咽喉头颈外科杂志编辑委员会,中华医学会耳
参考文献 鼻咽喉头颈外科学分会 . 突发性聋诊断和治疗指南:
[ 1 ] PRINCE A D P,STUCKEN E Z. Sudden sensorineural 2015[J]. 中华耳鼻咽喉头颈外科杂志,2015,50(6):
hearing loss:a diagnostic and therapeutic emergency[J]. J 443-447.
Am Board Fam Med,2021,34(1):216-223. [13] CHADHA S,KAMENOV K,CIEZA A. The world report
[ 2 ] 马肃威,王大勇,王秋菊. 突发性聋程度分级与疗效研究 on hearing,2021[J]. Bull World Health Organ,2021,99
进展[J]. 中华耳科学杂志,2025,23(5):677-682. (4):242-242A.
[ 3 ] YOUNG Y H. Contemporary review of the causes and [14] 王倩滢,雷艳,潘小燕,等. 突发性耳聋耳鸣与特发性耳
differential diagnosis of sudden sensorineural hearing loss 鸣的临床特征比较[J]. 中华耳科学杂志,2024,22(3):
[J]. Int J Audiol,2020,59(4):243-253. 367-371.
[ 4 ] LIN C Y,CHANG C H,CHANG C J,et al. Salvage [15] 王崇,王建明,杨威,等. 眩晕残障程度评定量表在良性
therapy for refractory sudden sensorineural hearing loss 阵发性位置性眩晕患者中的应用[J]. 中华全科医师杂
(RSSNHL):a systematic review and network meta- 志,2016,15(7):550-552.
analysis[J]. Int J Audiol,2025,64(1):1-10. [16] LEE H A,CHUNG J H. Contemporary review of idio‐
[ 5 ] MIRSALEHI M,GHAJARZADEH M,FARHADI M, pathic sudden sensorineural hearing loss:management and
et al. Intratympanic corticosteroid injection as a first-line prognosis[J]. J Audiol Otol,2024,28(1):10-17.
treatment of the patients with idiopathic sudden sensori‐ [17] PAPADOPOULOU A M,PAPOULIAKOS S,KARKOS
neural hearing loss compared to systemic steroid:a sys‐ P,et al. The impact of cardiovascular risk factors on the
tematic review and meta-analysis[J]. Am J Otolaryngol, incidence,severity,and prognosis of sudden sensorineural
2022,43(5):103505. hearing loss (SSHL):a systematic review[J]. Cureus,
[ 6 ] JOSHUA T G,AYUB A,WIJESINGHE P,et al. Hyper‐ 2024,16(4):e58377.
baric oxygen therapy for patients with sudden sensorineu‐ [18] LAN D,JIAO B L,SONG S Y,et al. Effects of batroxo‐
ral hearing loss:a systematic review and meta-analysis[J]. bin on the antithrombotic system in patients with cerebral
JAMA Otolaryngol Head Neck Surg,2022,148(1):5-11. venous thrombosis:clues to mechanisms[J]. CNS Neuro‐
[ 7 ] ZHANG D,LI D B,CHEN T,et al. Intratympanic lido‐ sci Ther,2024,30(8):e14861.
caine as a potent remedy for tinnitus in sudden sensorineu‐ [19] CHEN A P,LIU W W,XU L,et al. Comparison of the
ral hearing loss:a double-blind,randomized clinical trial pathway to the inner ear between postauricular and intra‐
[J]. Otol Neurotol,2024,45(8):849-854. muscular injection of dexamethasone in guinea pigs[J].
[ 8 ] TSUZUKI N,WASANO K. Idiopathic sudden sensorineu‐ Front Neurol,2022,13:811626.
ral hearing loss:a review focused on the contribution of [20] CHEN J,FRASER-KIRK K. Management of sudden sen‐
vascular pathologies[J]. Auris Nasus Larynx,2024,51 sorineural hearing loss:a time-critical diagnosis[J]. Aust J
(4):747-754. Gen Pract,2024,53(Suppl.11):S14-S18.
[ 9 ] KITOH R,NISHIO S Y,SATO H,et al. Clinical practice (收稿日期:2025-10-13 修回日期:2026-02-24)
guidelines for the diagnosis and management of acute sen‐ (编辑:胡晓霖)
sorineural hearing loss[J]. Auris Nasus Larynx,2024,51
· 644 · China Pharmacy 2026 Vol. 37 No. 5 中国药房 2026年第37卷第5期

