Page 102 - 《中国药房》2026年5期
P. 102

应方面更具有优势,而鼓室内注射可能更适合听力损失                                (4):811-821.
          程度较重的患者,这为突聋个体化治疗提供了新选择。                            [10]  CHEW S C,MD DAUD M K. The efficacy of intratym‐
          未来应致力于构建基于病理分型、损伤程度和临床特征                                 panic steroid injection for the treatment of idiopathic sud‐
          的精准治疗体系,最终改善患者听力预后和生活质量。                                 den sensorineural hearing loss[J]. Med J Malaysia,2020,
          本研究亦存在一定的局限性:作为单中心回顾性研究,                                 75(1):74-77.
                                                              [11]  CHRYSOULI K,KOLLIA P,PAPANIKOLAOU V,et al.
          样本量相对有限,且部分亚组病例数偏少;同时,本研究
                                                                   The  effectiveness  of  intratympanic  steroid  injection  in
          主要评价的是短期疗效,未能获得统一时间点的长期随
                                                                   addition  to  systemic  corticosteroids  in  the  treatment  of
          访数据,这些均会给研究结果带来一定的偏倚。因此,
                                                                   idiopathic  sudden  sensorineural  hearing  loss[J].  Am  J
          本文所得结论仍需在更大样本的前瞻性研究中进一步
                                                                   Otolaryngol,2023,44(4):103872.
          验证。
                                                              [12]  中华耳鼻咽喉头颈外科杂志编辑委员会,中华医学会耳
          参考文献                                                     鼻咽喉头颈外科学分会 . 突发性聋诊断和治疗指南:
          [ 1 ]  PRINCE A  D  P,STUCKEN  E  Z.  Sudden  sensorineural   2015[J]. 中华耳鼻咽喉头颈外科杂志,2015,50(6):
               hearing loss:a diagnostic and therapeutic emergency[J]. J   443-447.
               Am Board Fam Med,2021,34(1):216-223.           [13]  CHADHA S,KAMENOV K,CIEZA A. The world report
          [ 2 ]  马肃威,王大勇,王秋菊. 突发性聋程度分级与疗效研究                        on  hearing,2021[J].  Bull World  Health  Organ,2021,99
               进展[J]. 中华耳科学杂志,2025,23(5):677-682.                 (4):242-242A.
          [ 3 ]  YOUNG  Y  H.  Contemporary  review  of  the  causes  and    [14]  王倩滢,雷艳,潘小燕,等. 突发性耳聋耳鸣与特发性耳
               differential diagnosis of sudden sensorineural hearing loss  鸣的临床特征比较[J]. 中华耳科学杂志,2024,22(3):
               [J]. Int J Audiol,2020,59(4):243-253.               367-371.
          [ 4 ]  LIN  C  Y,CHANG  C  H,CHANG  C  J,et  al.  Salvage   [15]  王崇,王建明,杨威,等. 眩晕残障程度评定量表在良性
               therapy  for  refractory  sudden  sensorineural  hearing  loss   阵发性位置性眩晕患者中的应用[J]. 中华全科医师杂
              (RSSNHL):a  systematic  review  and  network  meta-  志,2016,15(7):550-552.
               analysis[J]. Int J Audiol,2025,64(1):1-10.     [16]  LEE  H A,CHUNG  J  H.  Contemporary  review  of  idio‐
          [ 5 ]  MIRSALEHI  M,GHAJARZADEH  M,FARHADI  M,           pathic sudden sensorineural hearing loss:management and
               et al. Intratympanic corticosteroid injection as a first-line   prognosis[J]. J Audiol Otol,2024,28(1):10-17.
               treatment  of  the  patients  with  idiopathic  sudden  sensori‐  [17]  PAPADOPOULOU  A  M,PAPOULIAKOS  S,KARKOS
               neural  hearing  loss  compared  to  systemic  steroid:a  sys‐  P,et al. The impact of cardiovascular risk factors on the
               tematic  review  and  meta-analysis[J]. Am  J  Otolaryngol,  incidence,severity,and prognosis of sudden sensorineural
               2022,43(5):103505.                                  hearing  loss (SSHL):a  systematic  review[J].  Cureus,
          [ 6 ]  JOSHUA T G,AYUB A,WIJESINGHE P,et al. Hyper‐      2024,16(4):e58377.
               baric oxygen therapy for patients with sudden sensorineu‐  [18]  LAN D,JIAO B L,SONG S Y,et al. Effects of batroxo‐
               ral hearing loss:a systematic review and meta-analysis[J].   bin on the antithrombotic system in patients with cerebral
               JAMA Otolaryngol Head Neck Surg,2022,148(1):5-11.   venous thrombosis:clues to mechanisms[J]. CNS Neuro‐
          [ 7 ]  ZHANG D,LI D B,CHEN T,et al. Intratympanic lido‐  sci Ther,2024,30(8):e14861.
               caine as a potent remedy for tinnitus in sudden sensorineu‐  [19]  CHEN A  P,LIU W W,XU  L,et  al.  Comparison  of  the
               ral hearing loss:a double-blind,randomized clinical trial  pathway to the inner ear between postauricular and intra‐
               [J]. Otol Neurotol,2024,45(8):849-854.              muscular  injection  of  dexamethasone  in  guinea  pigs[J].
          [ 8 ]  TSUZUKI N,WASANO K. Idiopathic sudden sensorineu‐  Front Neurol,2022,13:811626.
               ral  hearing  loss:a  review  focused  on  the  contribution  of   [20]  CHEN J,FRASER-KIRK K. Management of sudden sen‐
               vascular  pathologies[J].  Auris  Nasus  Larynx,2024,51  sorineural hearing loss:a time-critical diagnosis[J]. Aust J
              (4):747-754.                                         Gen Pract,2024,53(Suppl.11):S14-S18.
          [ 9 ]  KITOH R,NISHIO S Y,SATO H,et al. Clinical practice         (收稿日期:2025-10-13  修回日期:2026-02-24)
               guidelines for the diagnosis and management of acute sen‐                          (编辑:胡晓霖)
               sorineural  hearing  loss[J]. Auris  Nasus  Larynx,2024,51





          · 644 ·    China Pharmacy  2026 Vol. 37  No. 5                               中国药房  2026年第37卷第5期
   97   98   99   100   101   102   103   104   105   106   107