Page 83 - 《中国药房》2026年2期

（1）：587. macol，2024，15：1298409.
[ 5 ] FALK E，SCHLIEPER D，VAN CASTER P，et al. A rapid [14] 万幸，杨青青，樊迪，等. 亚麻醉剂量艾司氯胺酮复合丙
positive influence of S-ketamine on the anxiety of patients 泊酚应用于无痛胃肠镜检查的效果[J]. 临床麻醉学杂
in palliative care：a retrospective pilot study[J]. BMC Pal‐ 志，2022，38（2）：144-148.
liat Care，2020，19（1）：1. [15] SZUHANY K L，SIMON N M. Anxiety disorders：a re‐
[ 6 ] ZHANG Y，LI S Q，WU C，et al. Effect of perioperative view[J]. JAMA，2022，328（24）：2431-2445.
subanesthetic dose of esketamine on postoperative reco- [16] KOPRA E，MONDELLI V，PARIANTE C，et al. Keta-
very quality in patients undergoing laparoscopic gastroin‐ mine’s effect on inflammation and kynurenine pathway in
testinal surgery：a randomised，double-blind，controlled depression：a systematic review[J]. J Psychopharmacol，
trial[J]. Drug Des Devel Ther，2025，19：6637-6646. 2021，35（8）：934-945.
[ 7 ] FERNÁNDEZ-CASTRO M，JIMÉNEZ J M，MARTÍN- [17] PEIRCE J M，ALVIÑA K. The role of inflammation and
GIL B，et al. The influence of preoperative anxiety on the gut microbiome in depression and anxiety[J]. J Neuro‐
postoperative pain in patients undergoing cardiac surgery sci Res，2019，97（10）：1223-1241.
[J]. Sci Rep，2022，12（1）：16464. [18] HALARIS A，COOK J. The glutamatergic system in
[ 8 ] RIZZO M G Jr，COSTELLO J P 2nd，LUXENBURG D， treatment-resistant depression and comparative effective‐
et al. Augmented reality for perioperative anxiety in pa‐ ness of ketamine and esketamine：role of inflammation?
tients undergoing surgery：a randomized clinical trial[J]. [M]//Neuroinflammation，gut-brain axis and immunity in
JAMA Netw Open，2023，6（8）：e2329310. neuropsychiatric disorders. Singapore：Springer Nature
[ 9 ] HAUCK A G V，VAN DER VAART M，ADAMS E，et al. Singapore，2023：487-512.
Effect of parental touch on relieving acute procedural pain [19] BRINCK E C V，VIRTANEN T，MÄKELÄ S，et al.
in neonates and parental anxiety（Petal）：a multicentre， S-ketamine in patient-controlled analgesia reduces opioid
randomised controlled trial in the UK[J]. Lancet Child consumption in a dose-dependent manner after major lum‐
Adolesc Health，2024，8（4）：259-269. bar fusion surgery：a randomized，double-blind，placebo-
[10] CHO S，KIM Y J，LEE M J，et al. Cut-off points between controlled clinical trial[J]. PLoS One，2021，16（6）：
pain intensities of the postoperative pain using receiver e0252626.
operating characteristic（ROC）curves[J]. BMC Anesthesiol， [20] PEREZ-RUIXO C，ROSSENU S，ZANNIKOS P，et al.
2021，21（1）：29. Population pharmacokinetics of esketamine nasal spray
[11] LI S，LIU H，ZHANG J，et al. The 95% effective dose of and its metabolite noresketamine in healthy subjects and
intranasal dexmedetomidine sedation for pulmonary func‐ patients with treatment-resistant depression[J]. Clin Phar‐
tion testing in children aged 1-3 years：a biased coin de‐ macokinet，2021，60（4）：501-516.
sign up-and-down sequential method[J]. J Clin Anesth， [21] TRIMMEL H，HELBOK R，STAUDINGER T，et al. S
2020，63：109746. （+）-ketamine：current trends in emergency and intensive
[12] HAWKER G A，MIAN S，KENDZERSKA T，et al. Mea‐ care medicine[J]. Wien Klin Wochenschr，2018，130（9/
sures of adult pain：visual analog scale for pain（VAS 10）：356-366.
pain），numeric rating scale for pain（NRS pain），McGill [22] BELL R F，DAHL J B，MOORE R A，et al. Peri-operative
pain questionnaire（MPQ），short-form McGill pain ques‐ ketamine for acute post-operative pain：a quantitative and
tionnaire（SF-MPQ），chronic pain grade scale（CPGS）， qualitative systematic review（cochrane review）[J]. Acta
short form-36 bodily pain scale（SF-36 BPS），and mea‐ Anaesthesiol Scand，2005，49（10）：1405-1428.
sure of intermittent and constant osteoarthritis pain [23] PIPER S N，BESCHMANN R B，MENGISTU A，et al.
（ICOAP）[J]. Arthritis Care Res（Hoboken），2011，63 Postoperative analgosedation with S（+）-ketamine de‐
（Suppl.11）：S240-S252. creases the incidences of postanesthetic shivering and nau‐
[13] CHU T T，ZHOU S Q，WAN Y F，et al. Comparison of sea and vomiting after cardiac surgery[J]. Med Sci Monit，
remimazolam and propofol combined with low dose esketa- 2008，14（12）：PI59-PI65.
mine for pediatric same-day painless bidirectional endos‐ （收稿日期：2025-07-23 修回日期：2025-12-26）
copy：a randomized，controlled clinical trial[J]. Front Phar‐ （编辑：陈 宏）

中国药房 2026年第37卷第2期 China Pharmacy 2026 Vol. 37 No. 2 · 209 ·