Page 37 - 《中国药房》2026年2期

2017，130（16）：1800-1808. [18] WANG H，DU Y Y，JI J，et al. Utilizing network toxico-
[ 4 ] ZHANG J，GU Y，CHEN B A. Drug-resistance mecha‐ logy and molecular dynamics simulations to efficiently
nism and new targeted drugs and treatments of relapse and evaluate the neurotoxicity and underlying mechanisms of
refractory DLBCL[J]. Cancer Manag Res，2023，15： the endocrine-disrupting chemical triclosan[J]. Int J Mol
245-255. Sci，2025，26（19）：9458.
[ 5 ] ZHANG G F，QIN Y M，LIU S B，et al. Bibliometric [19] WANG Y，WANG W H，LIU K L，et al. The mechanism
analysis of research trends and topic areas in traditional of Xihuang pills’ intervention in the tumour immune mi‐
Chinese medicine therapy for lymphoma[J]. Pharm Biol， croenvironment for the treatment of liver cancer based on
the STAT3-PDL1 pathway[J]. J Ethnopharmacol，2024，
2024，62（1）：13-21.
331：118278.
[ 6 ] 王洪绪 . 外科证治全生集[M]. 北京：人民卫生出版社，
[20] 吴若霞，陈锦东，李松辉，等 . 西黄丸抗肿瘤作用机制的
1989：36.
研究进展[J].湖南中医杂志，2021，37（12）：190-192.
[ 7 ] 国家药典委员会. 中华人民共和国药典：一部[M]. 2020
[21] EL HAMEED EBID O A，EZZ EL ARAB L R，SAAD A S，
年版. 北京：中国医药科技出版社，2020：876-877.
et al. Prognostic impact of MYD88 and TP53 mutations in
[ 8 ] GUO Q J，LIN J Y，LIU R，et al. Review on the applica‐
diffuse large B Cell lymphoma[J]. Ann Hematol，2023，
tions and molecular mechanisms of Xihuang pill in tumor
102（12）：3477-3488.
treatment[J]. Evid Based Complement Alternat Med，
[22] WANG P H，MA Y，RAO X H，et al. Kaempferol targets
2015，2015：854307.
Src to exert its chemopreventive effects on mammary tu‐
[ 9 ] CAO B，WANG S Y，LI R S，et al. Xihuang pill enhances
morigenesis via regulation of the PI3K/AKT pathway[J].
anticancer effect of anlotinib by regulating gut microbiota Phytomedicine，2025，141：156701.
composition and tumor angiogenesis pathway[J]. Biomed [23] PEIRÓ G，ORTIZ-MARTÍNEZ F，GALLARDO A，et al.
Pharmacother，2022，151：113081. Src，a potential target for overcoming trastuzumab resis‐
[10] CHEN C，YUAN S M，CHEN X H，et al. Xihuang pill in‐ tance in HER2-positive breast carcinoma[J]. Br J Cancer，
duces pyroptosis and inhibits progression of breast cancer 2014，111（4）：689-695.
cells via activating the cAMP/PKA signalling pathway[J]. [24] LANTERMANS H C，MINDERMAN M，KUIL A，et al.
Am J Cancer Res，2023，13（4）：1347-1362. Identification of the SRC-family tyrosine kinase HCK as a
[11] CHEN Z H，LI Z M，YANG S，et al. The prospect of Xi‐ therapeutic target in mantle cell lymphoma[J]. Leukemia，
huang pill in the treatment of cancers[J]. Heliyon，2023，9 2021，35（3）：881-886.
（4）：e15490. [25] ZHANG N N，ZHANG G，LIU N，et al. A novel orally
[12] MAO D，FENG L，HUANG S Q，et al. Meta-analysis of available Syk/Src/Jak2 inhibitor，SKLB-850，showed po‐
Xihuang pill efficacy when combined with chemotherapy tent anti-tumor activities in B cell lymphoma（BCL）mo-
for treatment of breast cancer[J]. Evid Based Complement dels[J]. Oncotarget，2017，8（67）：111495-111507.
Alternat Med，2019，2019：3502460. [26] CHEN J F，GE X W，ZHANG W，et al. PI3K/AKT inhibi‐
[13] 董旭辉. 西黄丸联合CHOP方案治疗B细胞非霍奇金淋 tion reverses R-CHOP resistance by destabilizing SOX2
in diffuse large B cell lymphoma[J]. Theranostics，2020，
巴瘤临床疗效[J]. 中医药临床杂志，2018，30（8）：1492-
10（7）：3151-3163.
1494.
[27] SADAQAT M，QASIM M，TAHIR UL QAMAR M，et al.
[14] 王钧. 西黄丸联合CHOP方案治疗非霍奇金淋巴瘤的效
Advanced network pharmacology study reveals multi-
果探析[J]. 当代医药论丛，2019，17（9）：175-176.
pathway and multi-gene regulatory molecular mechanism
[15] ZHAO L，ZHANG H，LI N，et al. Network pharmacology，
of Bacopa monnieri in liver cancer based on data mining，
a promising approach to reveal the pharmacology mecha‐
molecular modeling，and microarray data analysis[J].
nism of Chinese medicine formula[J]. J Ethnopharmacol，
Comput Biol Med，2023，161：107059.
2023，309：116306.
[28] SULEMAN M，YOUSAFI Q，ALI J，et al. Bioinformatics
[16] WU X D，XU L Y，LI E M，et al. Application of molecular analysis of the differences in the binding profile of the
dynamics simulation in biomedicine[J]. Chem Biol Drug wild-type and mutants of the SARS-CoV-2 spike protein
Des，2022，99（5）：789-800. variants with the ACE2 receptor[J]. Comput Biol Med，
[17] RU J L，LI P，WANG J N，et al. TCMSP：a database of 2021，138：104936.
systems pharmacology for drug discovery from herbal （收稿日期：2025-09-08 修回日期：2025-12-15）
medicines[J]. J Cheminform，2014，6：13. （编辑：舒安琴）

中国药房 2026年第37卷第2期 China Pharmacy 2026 Vol. 37 No. 2 · 167 ·