Page 109 - 《中国药房》2025年23期
P. 109

合并心血管高风险的 T2DM 患者,如以降糖、减重和降                             [J]. Value Health,2022,25(1):10-31.
          压为主要目标,可优先考虑卡格列净,但应警惕其低血                           [12]  DONNAN  J  R,GRANDY  C  A,CHIBRIKOV  E,et  al.
          糖发生风险。(2)与其他 SGLT-2 抑制剂相比,恩格列净                          Dose  response  of  sodium  glucose  cotransporter-2  inhibi‐
          总体安全性更优。(3)尿路感染易发人群慎用达格列净。                              tors in relation to urinary tract infections:a systematic re‐
         (4)经济学证据支持恩格列净和卡格列净的经济性优于                                view and network meta-analysis of randomized controlled
                                                                  trials[J]. CMAJ Open,2018,6(4):E594-E602.
          达格列净,且恩格列净更具优势,但仍需开展基于我国
                                                             [13]  LI C X,LIU L Y,ZHANG C X,et al. Comparative safety
          真实世界数据的经济学评价。(5)建议将恩格列净纳入
                                                                  of different sodium-glucose transporter 2 inhibitors in pa‐
          国家基本药物目录,以提升基层可及性;在集采续约中
                                                                  tients  with  type  2  diabetes:a  systematic  review  and  net‐
          优先支持卡格列净和恩格列净,保障其供应与价格可
                                                                  work  meta-analysis  of  randomized  controlled  trials[J].
          控;结合用药风险完善医保报销政策,确保高风险人群                                Front Endocrinol,2023,14:1238399.
          安全用药。                                              [14]  禚君,令娟,江燕,等. SGLT-2抑制剂致2型糖尿病患者
          参考文献                                                    低血糖的网状 Meta 分析[J]. 中国药房,2023,34(12):
          [ 1 ]  中华医学会糖尿病学分会 . 中国糖尿病防治指南:2024                     1509-1514.
              版[J]. 中华糖尿病杂志,2025,17(1):16-139.               [15]  SHYANGDAN D S,UTHMAN O A,WAUGH N. SGLT-
          [ 2 ]  REIFSNIDER O S,KANSAL A R,GANDHI P K,et al.      2 receptor inhibitors for treating patients with type 2 diabe‐
              Cost-effectiveness  of  empagliflozin  versus  canagliflozin,  tes  mellitus:a  systematic  review  and  network  meta-
              dapagliflozin,or standard of care in patients with type 2   analysis[J]. BMJ Open,2016,6(2):e009417.
              diabetes  and  established  cardiovascular  disease[J].  BMJ   [16]  WANG  H  M,YANG  J  D,CHEN  X,et  al.  Effects  of
              Open Diabetes Res Care,2021,9(1):e001313.           sodium-glucose cotransporter 2 inhibitor monotherapy on
          [ 3 ]  YANG S W,LIU Y,ZHANG S Z,et al. Risk of diabetic   weight changes in patients with type 2 diabetes mellitus:a
              ketoacidosis  of  SGLT2  inhibitors  in  patients  with  type  2   Bayesian  network  meta-analysis[J].  Clin  Ther,2019,41
              diabetes:a  systematic  review  and  network  meta-analysis   (2):322-334.e11.
              of randomized controlled trials[J]. Front Pharmacol,2023,  [17]  CHEN M B,WANG H,CUI W Y,et al. Effect of SGLT
              14:1145587.                                         inhibitors on weight and lipid metabolism at 24 weeks of
          [ 4 ]  刘凤琪,柴三葆,赵厚宇,等. 钠-葡萄糖共转运蛋白2抑                      treatment  in  patients  with  diabetes  mellitus:a  systematic
              制剂引起 2 型糖尿病患者尿路或生殖器感染风险的网                           review  and  network  meta-analysis[J].  Medicine(Balti‐
              状Meta分析[J]. 中华糖尿病杂志,2022,14(8):799-808.             more),2021,100(6):e24593.
          [ 5 ]  孔文强. 钠-葡萄糖共转运蛋白-2抑制剂治疗2型糖尿病                 [18]  HEGDE  N  C,KUMAR  A,PATIL  A  N,et  al.  Dose-
              疗效与安全性的网状 Meta 分析[D]. 泸州:西南医科大                      dependent renoprotection efficacy of SGLT-2 inhibitors in
              学,2019.                                             type  2  diabetes:systematic  review  and  network  meta-
          [ 6 ]  林宇豪 . GLP-1 受体激动剂与 SGLT-2 抑制剂对超重/肥               analysis[J]. Acta Diabetol,2023,60(10):1311-1331.
              胖伴或不伴糖尿病患者疗效和安全性的网状Meta分析                      [19]  王娜娜. SGLT2抑制剂治疗2型糖尿病合并心血管疾病
              [D]. 福州:福建医科大学,2022.                                的有效性和安全性的 Meta 分析[D]. 宜春:宜春学院,
          [ 7 ]  GOURZOULIDIS G,TZANETAKOS C,IOANNIDIS I,         2022.
              et  al.  Cost-effectiveness  of  empagliflozin  compared  with   [20]  王润青,王谦,廖健雄. SGLT2抑制剂对2型糖尿病患者
              dapagliflozin for the treatment of patients with type 2 dia‐  心血管结局影响的网状 Meta 分析[J]. 临床荟萃,2022,
              betes  mellitus  and  established  cardiovascular  disease  in   37(12):1061-1073.
              Greece[J]. Clin Drug Investig,2021,41(4):371-380.  [21]  TENG Y J,FAN X,YU R,et al. Evaluation and compari‐
          [ 8 ]  唐惠林,门鹏,翟所迪,等. 药物快速卫生技术评估方法                       son  of  efficacy  and  safety  of  tirzepatide,liraglutide  and
              及应用[J]. 临床药物治疗杂志,2016,14(2):1-4.                    SGLT2i  in  patients  with  type  2  diabetes  mellitus:a  net‐
          [ 9 ]  HAILEY  D.  Toward  transparency  in  health  technology     work  meta-analysis[J].  BMC  Endocr  Disord,2024,24
              assessment:a checklist for HTA reports[J]. Int J Technol   (1):278.
              Assess Health Care,2003,19(1):1-7.             [22]  LI  D  D,WANG  T  S,SHEN  S,et  al.  Urinary  tract  and
          [10]  SHEA B J,REEVES B C,WELLS G,et al. AMSTAR 2:a     genital infections in patients with type 2 diabetes treated
              critical  appraisal  tool  for  systematic  reviews  that  include   with  sodium-glucose  co-transporter  2  inhibitors:a  meta-
              randomised or non-randomised studies of healthcare inter‐  analysis of randomized controlled trials[J]. Diabetes Obes
              ventions,or both[J]. BMJ,2017,358:j4008.            Metab,2017,19(3):348-355.
          [11]  HUSEREAU  D,DRUMMOND  M,AUGUSTOVSKI  F,      [23]  ZACCARDI F,WEBB D R,HTIKE Z Z,et al. Efficacy
              et  al.  Consolidated  health  economic  evaluation  reporting   and  safety  of  sodium-glucose  co-transporter-2  inhibitors
              standards(CHEERS)2022 explanation and elaboration:a   in type 2 diabetes mellitus:systematic review and network
              report of the ISPOR CHEERS Ⅱ good practices task force  meta-analysis[J].  Diabetes  Obes  Metab,2016,18(8):


          中国药房  2025年第36卷第23期                                              China Pharmacy  2025 Vol. 36  No. 23    · 2983 ·
   104   105   106   107   108   109   110   111   112   113   114