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基于多准则决策分析的县域医共体药品目录遴选体系构建与实证                                                                      Δ



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          郭艺楠    1, 2* ,俞秀恒 ,谢雨晴 ,向世欣 ,林 欢 ,龙友琦 ,赵 语 (1.重庆医科大学药学院,重庆 400016;
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          2.重庆医科大学附属大学城医院药学部,重庆 401331)
          中图分类号  R95      文献标志码  A      文章编号  1001-0408(2025)08-0914-06
          DOI  10.6039/j.issn.1001-0408.2025.08.04
          摘   要  目的  探索构建基于多准则决策分析的县域医共体药品目录遴选体系,为医共体药品目录的遴选提供决策依据。方法
          以重庆市某县域医共体为例,采用德尔菲法和层次分析法构建县域医共体药品目录遴选体系;按照所构建的指标体系对待遴选药
          品进行量化评分,再依据药品综合评分遴选药品目录;在该目录实施1年后通过问卷调查评估目录的实施效果。结果  两轮德尔
          菲法专家咨询的专家权威系数均大于0.8,Kendall’s W分别为0.213和0.196(P均小于0.001)。最终确定的药品目录遴选体系包括
          安全性、有效性、经济性、可及性、创新性5个评价维度,共8个评价指标。按上述方法遴选的药品目录中,集采药品、医保药品、基
          本药物数目占比均较遴选前有所升高;化学药品的综合评分为50.25~96.31分,70~100分的药品占比由遴选前的78.06%上升为
          85.82%,其中抗虫药的综合评分最高,消化道及代谢类药数量最多;遴选后药品目录中药品的各指标评分和综合评分均较遴选前
          显著升高(P<0.05)。结论  本研究构建的县域医共体药品目录遴选体系科学客观、可操作性强,有利于促进医共体药品的规范化
          统一管理。
          关键词  县域医共体;药品目录;药品遴选;多准则决策分析;评价指标体系;循证证据

          Construction  and  empirical  study  of  selection  system  for   drug  directory  of  county-level  medical
          community based on multi-criteria decision analysis
          GUO Yinan ,YU Xiuheng ,XIE Yuqing ,XIANG Shixin ,LIN Huan ,LONG Youqi ,ZHAO Yu(1. School of
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          Pharmaceutical  Sciences,  Chongqing  Medical  University,  Chongqing  400016,  China;2.  Dept.  of  Pharmacy,
          University-Town Hospital of Chongqing Medical University, Chongqing 401331, China)
          ABSTRACT    OBJECTIVE  To  explore  the  construction  of  selection  system  for  drug  directory  of  the  county-level  medical
          community  based  on  multi-criteria  decision  analysis,  and  provide  decision-making  basis  for  the  selection  of  drug  directory  of
          medical community. METHODS Taking county-level medical community in Chongqing as an example,Delphi method and analytic
          hierarchy  process  were  employed  to  construct  the  selection  system  for  drug  directory  of  the  county-level  medical  community.
          Selected  drugs  were  quantitatively  scored  based  on  the  constructed  index  system,  and  the  drug  directory  was  selected  according  to
          the  drug’s  comprehensive  score.  The  implementation  effect  of  the  directory  was  then  evaluated  through  questionnaire  surveys  one
          year after the implementation of the directory. RESULTS The expert authority coefficients of the two rounds of consultation were>
          0.8, with Kendall’s W values of 0.213 and 0.196, respectively (P<0.001). Finally, the selection system for drug directory of the
          medical  community  was  determined  to  include  five  evaluation  dimensions:  safety,  effectiveness,  economy,  accessibility,  and
          innovation, along with eight evaluation indicators. In the drug directory selected according to the above method, the proportions of
          centrally  procured  drugs,  medical  insurance  drugs,  and  essential  drugs  had  all  increased  compared  to  before  the  selection;  the
          comprehensive  scores  of  chemical  drugs  ranged  from  50.25  to  96.31  scores,  and  the  proportion  of  drugs  scoring  between  70  and
          100 scores had increased from 78.06% before selection to 85.82%. Among them, antiparasitic drugs had the highest comprehensive
          scores, while drugs for the digestive tract and metabolism were the most numerous. The evaluation scores of each indicator and the
          comprehensive  scores  of  drugs  in  the  drug  directory  after  the  selection  process  increased  significantly  than  before  selection (P<
          0.05). CONCLUSIONS The selection system for drug directory of the county-level medical community constructed in this study is
          scientific,  objective  and  operable.  This  process  facilitates  the  promotion  of  standardized  and  unified  management  of  drugs  in  the
          medical community.
          KEYWORDS     county-level medical community;  drug  directory;  drug  selection;  multi-criteria decision analysis;  evaluation index
                                                              system; evidence-based evidence
              Δ  基金项目 重 庆 市 卫 生 健 康 委 医 学 科 研 项 目(No. 2022-
          WSJK049)                                                县域医疗卫生共同体(简称“县域医共体”)是我国
             * 第一作者 硕 士 研 究 生 。 研 究 方 向 :临 床 药 学 。 E-mail:
                                                              深化医药卫生体制改革的重要举措之一,旨在通过整合
          2022120896@stu.cqmu.edu.cn
                                                              县域内医疗资源,提升基层医疗服务能力,实现分级诊
              # 通信作者 主任药师,硕士生导师,硕士。研究方向:药物新剂
                                                                    [1]
          型、医院药学。E-mail:zhaoyuu@hotmail.com                   疗目标 。2018 年 11 月,国家卫生健康委、国家中医药

          · 914 ·    China Pharmacy  2025 Vol. 36  No. 8                               中国药房  2025年第36卷第8期
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