Page 121 - 《中国药房》2024年3期
P. 121

tients with HER2  metastatic breast cancer after lapatinib   catinib  versus  placebo  added  to  trastuzumab  and
                           +
              and  trastuzumab  treatment (KCSG  BR11-16)[J].  Br  J   capecitabine for patients with pretreated HER2  metastatic
                                                                                                    +
              Cancer,2019,121(12):985-990.                        breast  cancer  with  and  without  brain  metastases
          [17]  UNTCH M,MINCKWITZ G V,GERBER B,et al. Sur‐       (HER2CLIMB):final  overall  survival  analysis[J].  Ann
              vival analysis after neoadjuvant chemotherapy with trastu‐  Oncol,2022,33(3):321-329.
              zumab  or  lapatinib  in  patients  with  human  epidermal   [24] HARBECK N,HUANGC S,HURVITZ S,et al. Afatinib
              growth factor receptor 2-positive breast cancer in the ge‐  plus vinorelbine versus trastuzumab plus vinorelbine in pa‐
              parquinto (G5) Study (GBG 44)[J]. J Clin Oncol,2018,  tients with HER2-overexpressing metastatic breast cancer
              36(13):1308-1316.                                   who  had  progressed  on  one  previous  trastuzumab  treat‐
          [18]  FERNANDEZ-MARTINEZ A,KROP I E,HILLMAN D           ment (LUX-Breast 1):an open-label,randomised,phase 3
              W,et al. Survival,pathologic response,and genomics in   trial[J]. Lancet Oncol,2016,17(3):357-366.
              CALGB 40601 (alliance),a neoadjuvant phase Ⅲ trial of   [25]  WU J,JIANG Z F,LIU Z Z,et al. Neoadjuvant pyrotinib,
              paclitaxel-trastuzumab with or without lapatinib in HER2-  trastuzumab,and docetaxel for HER2-positive breast can‐
              positive  breast  cancer[J].  J  Clin  Oncol,2020,38(35):  cer (PHEDRA):a double-blind,randomized phase 3 trial
              4184-4193.                                          [J]. BMC Med,2022,20(1):498.
          [19]  TAKANO T,TSURUTANI  J,TAKAHASHI  M,et  al. A   [26]  XU B,YAN M,MA F,et al. LBA19 Pyrotinib or placebo
              randomized  phase  Ⅱ  trial  of  trastuzumab  plus   in combination with trastuzumab and docetaxel for HER2-
              capecitabine versus lapatinib plus capecitabine in patients   positive metastatic breast cancer (PHILA):a randomized
              with  HER2-positive  metastatic  breast  cancer  previously   phase Ⅲ trial[J]. Ann Oncol,2022,33:S1387.
              treated  with  trastuzumab  and  taxanes:WJOG6110B/  [27]  DING Y Q,MO W J,XIE X H,et al. Pyrotinib as neoadju‐
              ELTOP[J]. Breast,2018,40:67-75.                     vant therapy for HER2+ breast cancer:a multicenter,ran‐
          [20]  PICCART-GEBHART  M,HOLMES  E,BASELGA  J,et        domized,controlled,phase Ⅱ trial[J]. J Clin Oncol,2021,
              al.  Adjuvant  lapatinib  and  trastuzumab  for  early  human   39(15_suppl):574.
              epidermal growth factor receptor 2-positive breast cancer:  [28]  JIANG  Z  F,YAN  M,BIAN  L,et  al. Abstract  PD8-05:
              results  from  the  randomized  phase  Ⅲ  adjuvant  lapatinib   overall survival (OS) results from the phase Ⅲ PHENIX
              and/or trastuzumab treatment optimization trial[J]. J Clin   trial of HER2+ metastatic breast cancer treated with pyro‐
              Oncol,2016,34(10):1034-1042.                        tinib  plus  capecitabine[J].  Cancer  Res, 2022, 82
          [21]  AWADA  A,COLOMER  R,INOUE  K,et  al.  Neratinib   (4_Supplement):5.
              plus  paclitaxel  vs  trastuzumab  plus  paclitaxel  in  pre-         [29]  YAN  M,BIAN  L,HU  X  C,et  al.  Pyrotinib  plus
              viously  untreated  metastatic  ERBB2-positive  breast        capecitabine for human epidermal growth factor receptor
              cancer:the NEfERT-T randomized clinical trial[J]. JAMA   2-positive  metastatic  breast  cancer  after  trastuzumab  and
              Oncol,2016,2(12):1557-1564.                         taxanes (PHENIX):a randomized,double-blind,placebo-
          [22]  CHAN A,MOY B,MANSI J,et al. Final efficacy results   controlled  phase  3  study[J].  Transl  Breast  Cancer  Res,
              of  neratinib  in  HER2-positive  hormone  receptor-positive   2020,1:13.
              early-stage breast cancer from the phase Ⅲ ExteNET trial      (收稿日期:2023-05-09  修回日期:2023-10-24)
              [J]. Clin Breast Cancer,2021,21(1):80-91.                                           (编辑:刘明伟)
          [23]  CURIGLIANO G,MUELLER V,BORGES V,et al. Tu‐





















          中国药房  2024年第35卷第3期                                                 China Pharmacy  2024 Vol. 35  No. 3    · 367 ·
   116   117   118   119   120   121   122   123   124   125   126