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pranolol reverses impaired fracture healing response ob‐ bone loss in mice by counteracting a local anti-resorptive
served with selective serotonin reuptake inhibitor treat‐ effect[J]. Nat Med,2016,22(10):1170-1179.
ment[J]. J Bone Miner Res,2020,35(5):932-941. [26] SIMS N A,MARTIN T J. Osteoclasts provide coupling
[14] GAO H,HUANG J M,WEI Q,et al. Advances in animal signals to osteoblast lineage cells through multiple mecha‐
models for studying bone fracture healing[J]. Bioenginee- nisms[J]. Annu Rev Physiol,2020,82:507-529.
ring,2023,10(2):201. [27] SHAFIEY S I,MOHAMED W R,ABO-SAIF A A. Paro-
[15] HOWIE R N,HERBERG S,DURHAM E,et al. Selective xetine and rivastigmine mitigates adjuvant-induced rheu‐
serotonin reuptake inhibitor sertraline inhibits bone hea- matoid arthritis in rats:impact on oxidative stress,apopto‐
ling in a calvarial defect model[J]. Int J Oral Sci,2018, sis and RANKL/OPG signals[J]. Life Sci,2018,212:
10(3):25. 109-118.
[16] SALAI M,SOMJEN D,GIGI R,et al. Effects of com‐ [28] SHEFTEL C M,SARTORI L C,HUNT E R,et al. Peripar‐
monly used medications on bone tissue mineralisation in tal treatment with low-dose sertraline accelerates mam‐
SaOS-2 human bone cell line:an in vitro study[J]. Bone mary gland involution and has minimal effects on mater‐
Joint J,2013,95-B(11):1575-1580. nal and offspring bone[J]. Physiol Rep,2022,10(5):
[17] DUCY P,KARSENTY G. The two faces of serotonin in e15204.
bone biology[J]. J Cell Biol,2010,191(1):7-13. [29] ZHANG H L,LI K F,ZHAO Y N,et al. Long-term use of
[18] KUMAR M,WADHWA R,KOTHARI P,et al. Differen‐ fluoxetine accelerates bone loss through the disruption of
tial effects of serotonin reuptake inhibitors fluoxetine and sphingolipids metabolism in bone marrow adipose tissue
escitalopram on bone markers and microarchitecture in [J]. Transl Psychiatry,2020,10(1):138.
Wistar rats[J]. Eur J Pharmacol,2018,825:57-62. [30] KOURA S M,SALAMA M,EL-HUSSINY M,et al.
[19] WADHWA R,KUMAR M,PAUDEL Y N,et al. Effect of Fluoxetine induces direct inhibitory effects on mesenchy‐
escitalopram and carbidopa on bone markers in Wistar mal stem cell-derived osteoprogenitor cells independent of
rats:a preliminary experimental study[J]. J Bone Miner serotonin concentration[J]. Mol Med Rep,2019,19(4):
Metab,2019,37(1):36-42. 2611-2619.
[20] KUMAR M,JILOHA R C,KATARIA D,et al. Effect of [31] KHADEMI M,TAGHIZADEH GHAVAMABADI R,
selective serotonin reuptake inhibitors on markers of bone TAGHAVI M M,et al. The effects of fluoxetine on the hu‐
loss[J]. Psychiatry Res,2019,276:39-44. man adipose-derived stem cell proliferation and differen‐
[21] MIYAMOTO K,OHKAWARA B,ITO M,et al. Fluo- tiation[J]. Fundam Clin Pharmacol,2019,33(3):286-295.
xetine ameliorates cartilage degradation in osteoarthritis [32] FERRONI L,GARDIN C,BELLIN G,et al. Effects of
by inhibiting Wnt/β-catenin signaling[J]. PLoS One,2017, novel antidepressant drugs on mesenchymal stem cell
12(9):e0184388. physiology[J]. Biomedecine Pharmacother,2019,114:
[22] TUNC-OZCAN E,BROOKER S M,BONDS J A,et al. 108853.
Hippocampal BMP signaling as a common pathway for [33] JAMES A W. Review of signaling pathways governing
antidepressant action[J]. Cell Mol Life Sci,2021, MSC osteogenic and adipogenic differentiation[J]. Scienti‐
79(1):31. fica,2013,2013:684736.
[23] TACHI J,ONUMA T,YAMAGUCHI S,et al. Duloxetine [34] KRUK J S,BERMEO S,SKARRATT K K,et al. The ef‐
suppresses BMP-4-induced release of osteoprotegerin via fect of antidepressants on mesenchymal stem cell differen‐
inhibition of the SMAD signaling pathway in osteoblasts tiation[J]. J Bone Metab,2018,25(1):43-51.
[J]. Biochim Biol Cell,2021,99(5):578-586. [35] ABU NADA L,SUBAIE A A,MANSOUR A,et al. The
[24] DURHAM E,ZHANG Y H,LARUE A,et al. Selective antidepressant drug,sertraline,hinders bone healing and
serotonin reuptake inhibitors (SSRI) affect murine bone osseointegration in rats’ tibiae[J]. J Clin Periodontol,
lineage cells[J]. Life Sci,2020,255:117827. 2018,45(12):1485-1497.
[25] ORTUÑO M J,ROBINSON S T,SUBRAMANYAM P, (收稿日期:2023-05-17 修回日期:2023-11-15)
et al. Serotonin-reuptake inhibitors act centrally to cause (编辑:胡晓霖)
中国药房 2023年第34卷第23期 China Pharmacy 2023 Vol. 34 No. 23 · 2933 ·