Page 113 - 《中国药房》2023年21期
P. 113
LI J,YANG J B,WANG Y Z. Applications of model- patibility of Chuanxiong Rhizoma and Astragali Radix[J].
informed drug development (MIDD) on new drug re‐ Chin Tradit Herb Drugs,2016,47(19):3463-3468.
search and development[J]. Chin J Clin Pharmacol Ther, [20] 潘洁,王昌权,李奎,等. 基于大鼠类风湿性关节炎模型
2020,25(1):1-8. 建立黑骨藤的 PK-PD 模型[J]. 中草药,2020,51(20):
[11] WANG X,LEE W Y W,ZHOU X L,et al. A 5194-5200.
pharmacodynamic-pharmacokinetic (PD-PK) study on PAN J,WANG C Q,LI K,et al. PK-PD model of Perip‐
the effects of Danshen (Salvia miltiorrhiza) on mida- loca forrestii based on rheumatiod arthritis rat model[J].
zolam,a model CYP3A probe substrate,in the rat[J]. Chin Tradit Herb Drugs,2020,51(20):5194-5200.
Phytomedicine,2010,17(11):876-883. [21] 谭兰芳,陈超,樊旭蕾,等. 基于PK-PD模型评价脑脉通
[12] FDA. Clinical drug interaction studies-study design,data 保护神经细胞的药效物质研究[J]. 中国中药杂志,2019,
analysis,and clinical implications guidance for industry, 44(12):2588-2593.
2017[EB/OL].(2017-10-25)[2023-08-04]. https://www. TAN L F,CHEN C,FAN X L,et al. Study on pharmaco‐
fda.gov/drugs/resources/clinical-drug-interaction-studies. dynamic material basis of Naomaitong to protect neuronal
[13] BUDHA N R,LEABMAN M,JIN J Y,et al. Modeling cells based on PK-PD model[J]. China J Chin Mater Med,
and simulation to support phase 2 dose selection for 2019,44(12):2588-2593.
RG7652,a fully human monoclonal antibody against pro‐ [22] 林力,刘建勋,张颖,等 . 中药复方双参通冠方的 PK/PD
protein convertase subtilisin/kexin type 9[J]. AAPS J, 数据分析研究[J]. 世界科学技术-中医药现代化,2012,
2015,17(4):881-890. 14(3):1583-1589.
[14] MANDEMA J W,SALINGER D H,BAUMGARTNER S LIN L,LIU J X,ZHANG Y,et al. A PK/PD data proces-
W,et al. A dose-response meta-analysis for quantifying sing study on Chinese formulation of Shuang-Shen-Tong-
relative efficacy of biologics in rheumatoid arthritis[J]. Guan prescription[J]. Mod Tradit Chin Med Mater Med-
Clin Pharmacol Ther,2011,90(6):828-835. World Sci Technol,2012,14(3):1583-1589.
[15] CHAN P,PESKOV K,SONG X Y. Applications of [23] 肖建鹏 . 基于网络药理学和 PK-PD 结合模型阐释酒女
model-based meta-analysis in drug development[J]. Pharm 贞子抗骨质疏松增效机理[D]. 镇江:江苏大学,2022.
Res,2022,39(8):1761-1777. XIAO J P. Synergistic mechanism of wine-processed Fruc‐
[16] 李雪,王磊,卜睿臻,等. 基于模型引导的中药安全用药 tus Ligustri Lucidi against osteoporosis integrated net‐
的研究策略:中药定量毒理学[J]. 中草药,2023,54(2): work pharmacology and PK-PD model[D]. Zhenjiang:
359-366. Jiangsu University,2022.
LI X,WANG L,BU R Z,et al. Model-guided research [24] WANG T Y,LIN S,LI H,et al. A stepwise integrated
strategies for safe use of traditional Chinese medicine: multi-system to screen quality markers of Chinese classic
quantitative toxicology of traditional Chinese medicine[J]. prescription Qingzao jiufei decoction on the treatment of
Chin Tradit Herb Drugs,2023,54(2):359-366. acute lung injury by combining ‘network pharmacology-
[17] 郑青山,陈凯先 . 基于模型的中药研发[J]. 世界科学技 metabolomics-PK/PD modeling’[J]. Phytomedicine,2020,
术-中医药现代化,2018,20(8):1269-1278. 78:153313.
ZHENG Q S,CHEN K X. Model-based Chinese medicine [25] 毕聪,郑如文,黄海涛,等. 小柴胡颗粒基于网络药理学
development[J]. Mod Tradit Chin Med Mater Med-World 的 组 方 配 伍 规 律 解 析 [J]. 药 学 研 究 ,2020,39(9):
Sci Technol,2018,20(8):1269-1278. 504-513.
[18] CHENG D,LI W J,WANG L J,et al. Pharmacokinetics, BI C,ZHENG R W,HUANG H T,et al. Network pharma‐
pharmacodynamics,and PKPD modeling of curcumin in cology based analysis of the formula rules of Xiaochaihu
regulating antioxidant and epigenetic gene expression in granules[J]. J Pharm Res,2020,39(9):504-513.
healthy human volunteers[J]. Mol Pharm,2019,16(5): [26] 寇俊萍,禹志领,龚树强,等. 小承气汤、厚朴大黄汤及厚
1881-1889. 朴三物汤药理作用[J]. 中成药,2004,26(1):57-59.
[19] 周惠芬,何昱,张宇燕,等. 川芎和黄芪有效部位组合给 KOU J P,YU Z L,GONG S Q,et al. The actions of Xiao‐
药后川芎嗪在脑缺血再灌注大鼠体内的 PK-PD 结合研 chengqi decoction,Houpudahuang decoction and Houpu‐
究[J]. 中草药,2016,47(19):3463-3468. sanwu decoction[J]. Chin Tradit Pat Med,2004,26(1):
ZHOU H F,HE Y,ZHANG Y Y,et al. Study on PK-PD 57-59.
combination of ligustrazine in cerebral ischemia reperfu‐ [27] 李晓萌,苏布达,黄志伟,等. 基于生理药动学模型预测
sion rats after ig administration of effective parts in com‐ 乌头碱在人体的药动学行为[J]. 中草药,2023,54(2):
中国药房 2023年第34卷第21期 China Pharmacy 2023 Vol. 34 No. 21 · 2663 ·