Page 83 - 《中国药房》2023年18期
P. 83
clinical trials[J]. Front Nutr,2023,10:1155306. nonalcoholic steatohepatitis[J]. N Engl J Med,2021,384
[14] ZHANG C S,TENG Y L,LI F Q,et al. Nanoparticle- (12):1113-1124.
mediated RNA therapy attenuates nonalcoholic steatohepa‐ [25] ARMSTRONG M J,GAUNT P,AITHAL G P,et al. Lira‐
titis and related fibrosis by targeting activated hepatic stel‐ glutide safety and efficacy in patients with non-alcoholic
late cells[J]. ACS Nano,2023,17(15):14852-14870. steatohepatitis(LEAN):a multicentre,double-blind,ran‐
[15] 段蓉,李正翔. 国内外药物警戒研究现状与热点的文献 domised,placebo-controlled phase 2 study[J]. Lancet,
计量学分析[J]. 中国药房,2022,33(1):116-122. 2016,387(10019):679-690.
[16] BANDYOPADHYAY S,SAMAJDAR S S,DAS S. [26] HARTMAN M L,SANYAL A J,LOOMBA R,et al.
Effects of saroglitazar in the treatment of non-alcoholic Effects of novel dual GIP and GLP-1 receptor agonist
fatty liver disease or non-alcoholic steatohepatitis:a tirzepatide on biomarkers of nonalcoholic steatohepatitis
systematic review and meta-analysis[J]. Clin Res Hepatol in patients with type 2 diabetes[J]. Diabetes Care,2020,43
Gastroenterol,2023,47(7):102174. (6):1352-1355.
[17] GOYAL N P,MENCIN A,NEWTON K P,et al. An open [27] RIZZO M,COLLETTI A,PENSON P E,et al. Nutraceutical
label,randomized,multicenter study of elafibranor in chil‐ approaches to non-alcoholic fatty liver disease(NAFLD):
dren with nonalcoholic steatohepatitis[J]. J Pediatr Gastro‐ a position paper from the International Lipid Expert Panel
enterol Nutr,2023,77(2):160-165. (ILEP)[J]. Pharmacol Res,2023,189:106679.
[18] FRANCQUE S M,BEDOSSA P,RATZIU V,et al. A ran‐ [28] SANYAL A,CHARLES E D,NEUSCHWANDER-
domized,controlled trial of the pan-PPAR agonist lanifi‐ TETRI B A,et al. Pegbelfermin(BMS-986036),a PEGylated
branor in NASH[J]. N Engl J Med,2021,385(17):1547- fibroblast growth factor 21 analogue,in patients with
1558. non-alcoholic steatohepatitis:a randomised,double-blind,
[19] NAKAJIMA A,EGUCHI Y,YONEDA M,et al. Ran‐ placebo-controlled,phase 2a trial[J]. Lancet,2019,392
domised clinical trial:pemafibrate,a novel selective (10165):2705-2717.
peroxisome proliferator-activated receptor α modulator [29] LI L M,SONG Y,SHI Y Q,et al. Thyroid hormone recep‐
(SPPARMα),versus placebo in patients with no-nalcoholic tor-β agonists in NAFLD therapy:possibilities and chal‐
fatty liver disease[J]. Aliment Pharmacol Ther,2021,54 lenges[J]. J Clin Endocrinol Metab,2023,108(7):1602-
(10):1263-1277. 1613.
[20] YOUNOSSI Z M,RATZIU V,LOOMBA R,et al. [30] RATZIU V,SANYAL A,HARRISON S A,et al. Cenicri‐
Obeticholic acid for the treatment of non-alcoholic steato‐ viroc treatment for adults with nonalcoholic steatohepatitis
hepatitis:interim analysis from a multicentre,randomised, and fibrosis:final analysis of the phase 2b centaur study
placebo-controlled phase 3 trial[J]. Lancet,2019,394 [J]. Hepatology,2020,72(3):892-905.
(10215):2184-2196. [31] XIE W T,SU F G,WANG G Z,et al. Glucose-lowering
[21] PATEL K,HARRISON S A,ELKHASHAB M,et al. Cilo‐ effect of berberine on type 2 diabetes:a systematic review
fexor,a nonsteroidal FXR agonist,in patients with noncir‐ and meta-analysis[J]. Front Pharmacol,2022,13:1015045.
rhotic NASH:a phase 2 randomized controlled trial[J]. [32] JIANG J J,ZHANG G F,ZHENG J Y,et al. Targeting
Hepatology,2020,72(1):58-71. mitochondrial ROS-mediated ferroptosis by quercetin
[22] RATZIU V,RINELLA M E,NEUSCHWANDER-TETRI alleviates high-fat diet-induced hepatic lipotoxicity[J]. Front
B A,et al. EDP-305 in patients with NASH:a phase Ⅱ Pharmacol,2022,13:876550.
double-blind placebo-controlled dose-ranging study[J]. J [33] 阮小风,张建军,杜鹏,等. 基于CiteSpace软件的非酒精
Hepatol,2022,76(3):506-517. 性脂肪性肝病治疗的可视化分析[J]. 华南国防医学杂
[23] 李政,陈莲如,刘玉霞. 非酒精性脂肪肝病药物研究进展 志,2019,33(12):815-822.
[J]. 聊城大学学报(自然科学版),2023,36(2):68-78. (收稿日期:2023-05-04 修回日期:2023-08-28)
[24] NEWSOME P N,BUCHHOLTZ K,CUSI K,et al. A (编辑:孙 冰)
placebo-controlled trial of subcutaneous semaglutide in
中国药房 2023年第34卷第18期 China Pharmacy 2023 Vol. 34 No. 18 · 2249 ·