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[24]
        腹高血糖主要是由肝脏糖异生所导致的 。PEPCK 和                              transcriptomics based investigation reveals an inhibitory
        G6Pase是肝脏糖异生过程中2种关键的限速酶,可通过                             role of Huanglian-Renshen-Decoction on hepatic glucose
                                    [25]
        抑制这2种酶来干预肝脏糖异生 。FoxO1是肝脏糖异                              production of T2DM mice via PI3K/Akt/FoxO1 signaling
        生关键酶调控的上游靶点,被磷酸化的FoxO1能够抑制                              pathway[J]. Phytomedicine,2021,83:153487.
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        研究结果显示,与模型组比较,茯苓多糖低、中、高剂量
                                                                学杂志,2020,26(1):78-86.
        组大鼠 PEPCK 和 G6Pase 蛋白表达水平均显著降低,表
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        明茯苓多糖可以抑制肝脏糖异生。
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        中国药房    2022年第33卷第13期                                             China Pharmacy 2022 Vol. 33 No. 13  ·1587 ·
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