Page 88 - 《中国药房》2021年22期
P. 88
比安慰剂二线治疗晚期 HCC 的经济性,结果表明,在 193-202.
1~3倍2020年我国人均GDP的WTP阈值下,帕博利珠 [11] European Association for the Study of the Liver. EASL
单抗方案不具经济性,而降低帕博利珠单抗成本可使其 clinical practice guidelines:management of hepatocellular
具有经济性的概率增大。 carcinoma[J]. J Hepatol,2018,69(1):182-236.
参考文献 [12] 刘国恩.中国药物经济学评价指南:2020[M].北京:中国
市场出版社,2020:27-46.
[ 1 ] SUNG H,FERLAY J,SIEGEL R L,et al. Global cancer
[13] NICHOLAS L. NICE DSU technical support document
statistics 2020:GLOBOCAN estimates of incidence and
14:survival analysis for economic evaluations alongside
mortality worldwide for 36 cancers in 185 countries[J].
clinical trials:extrapolation with patient-level data[EB/OL].
CA Cancer J Clin,2021,71(3):209-249.
[2021-10-25]. http://nicedsu.org.uk/wp-content/uploads/
[ 2 ] ZHANG P,YANG Y,WEN F,et al. Cost-effectiveness of
2016/03/NICE-DSU-TSD-Survival-analysis.updated-March-
sorafenib as a first-line treatment for advanced hepato-
2013.v2.pdf.
cellular carcinoma[J]. Eur J Gastroen Hepat,2015,27(7):
[14] 国家统计局.第六次人口普查汇总数据[EB/OL]. [2021-10-
853-859.
25]. http://www.stats.gov.cn/tjsj/pcsj/rkpc/6rp/indexch.
[ 3 ] 李洁琅,陈婷,杨雨. PD-1/PD-L1抑制剂在晚期肝细胞肝
htm.
癌治疗中的研究进展[J].中国肿瘤临床,2020,47(5):
[15] 周挺,马爱霞,付露阳.药物经济学评价Markov模型中转
265-268.
移概率计算的探讨[J].中国卫生经济,2017,36(12):
[ 4 ] BRUIX J ,QIN S ,MERLE P ,et al. Regorafenib for
40-42.
patients with hepatocellular carcinoma who progressed on
[16] PATTERSON K,PRABHU V,XU R,et al. Cost-effective-
sorafenib treatment(RESORCE):a randomised,double-
ness of pembrolizumab for patients with advanced,unre-
blind,placebo-controlled,phase 3 trial[J]. Lancet,2017,
sectable,or metastatic urothelial cancer ineligible for cis-
389(10064):56-66.
platin-based therapy[J]. Eur Urol Oncol,2019,2(5):
[ 5 ] ZHU A X,FINN R S,EDELINE J,et al. Pembrolizumab
565-571.
in patients with advanced hepatocellular carcinoma pre-
[17] PARIKH N D,SINGAL A G,HUTTON D W. Cost effec-
viously treated with sorafenib(KEYNOTE-224):a non-
tiveness of regorafenib as second-line therapy for patients
randomised,open-label phase 2 trial[J]. Lancet Oncol,
with advanced hepatocellular carcinoma[J]. Cancer,2017,
2018,19(7):940-952.
123(19):3725-3731.
[ 6 ] ABOU-ALFA G K,MEYER T,CHENG A L,et al. Cabo-
[18] CAMMÀ C,CABIBBO G,PETTA S,et al. Cost-effective-
zantinib in patients with advanced and progressing hepato-
ness of sorafenib treatment in field practice for patients
cellular carcinoma[J]. N Engl J Med,2018,379(1):54-63.
with hepatocellular carcinoma[J]. Hepatology,2013,57
[ 7 ] ZHU A X,KANG Y K,YEN C J,et al. Ramucirumab
(3):1046-1054.
after sorafenib in patients with advanced hepatocellular
[19] 徐赫,马爱霞.基于分区生存模型的帕博利珠单抗单药与
carcinoma and increased α-fetoprotein concentrations
化疗一线治疗 PD-L1 肿瘤比例分数不同的非小细胞肺
(REACH-2):a randomised,double-blind,placebo-con-
癌的成本-效果分析[J].中国医院药学杂志,2020,40
trolled,phase 3 trial[J]. Lancet Oncol,2019,20(2):282-
(23):2468-2473.
296.
[20] CAI H,ZHANG L,LI N,et al. Lenvatinib versus sorafenib
[ 8 ] YAU T,KANG Y K,KIM T Y,et al. Efficacy and safety
for unresectable hepatocellular carcinoma:a cost-effective-
of nivolumab plus ipilimumab in patients with advanced ness analysis[J]. J Comp Eff Res,2020,9(8):553-562.
hepatocellular carcinoma previously treated with sorafenib:
[21] 刘国强,康朔.阿替利珠单抗联合标准化疗方案治疗广泛
the checkmate 040 randomized clinical trial[J]. JAMA
期小细胞肺癌的成本-效用分析[J].中国药房,2021,32
Oncol,2020,6(11):e204564. (1):77-81.
[ 9 ] 中国临床肿瘤学会指南工作委员会.原发性肝癌诊疗指 [22] MEYERS B M,VOGEL A,MAROTTA P,et al. The
南 2020[EB/OL]. [2021-10-25]. http://www.amoydx.com/ cost-effectiveness of lenvatinibin the treatment of ad-
upfiles/reports/202103/1614847539702.pdf. vanced or unresectable hepatocellular carcinoma from a
[10] FINN R S,RYOO B Y,MERLE P,et al. Pembrolizumab Canadian perspective[J]. Can J Gastroenterol Hepatol,
as second-line therapy in patients with advanced hepato- 2021,2021:8811018.
cellular carcinoma in KEYNOTE-240:a randomized,dou- (收稿日期:2021-04-30 修回日期:2021-10-25)
ble-blind,phase Ⅲ trial[J]. J Clin Oncol,2020,38(3): (编辑:孙 冰)
·2766 · China Pharmacy 2021 Vol. 32 No. 22 中国药房 2021年第32卷第22期