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综上所述,相较于 MMF 联合糖皮质激素方案, phenolate mofetil among patients with progressive IgA
MMF 联合布地奈德肠溶胶囊治疗高风险进展 IgAN 患 nephropathy:a randomized clinical trial[J]. JAMA Netw
者,能更快速地减少蛋白尿、提升血清ALB水平,显著提 Open,2023,6(2):e2254054.
高治疗早期的有效率,并降低糖皮质激素相关皮肤不良 [ 8 ] 胡晓磊,张桂芬,郭庆寅 . 基于肠-肾轴机制对 IgA 肾病
反应、血糖升高以及总体不良反应的发生率,展现出更 靶向治疗的研究进展[J]. 宁夏医科大学学报,2022,44
(11):1176-1181.
优的短期效益。虽然两组患者在治疗6个月时的CR率
[ 9 ] LEVIN A,AHMED S B,CARRERO J J,et al. Executive
和肾功能指标水平趋于一致,但观察组患者更早达到病
summary of the KDIGO 2024 Clinical Practice Guideline
情缓解的优势可能对长期预后产生积极影响。
for the Evaluation and Management of Chronic Kidney
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(编辑:胡晓霖)
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· 932 · China Pharmacy 2026 Vol. 37 No. 7 中国药房 2026年第37卷第7期

