Page 103 - 《中国药房》2024年23期

·药师与药学服务·

基于药品监测大数据的内蒙古自治区儿童药品使用情况分析
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赵玉芳 1， 2＊ ，雷雯朴 ，刘治恩 ，杨胜男 ，张亚男 ，赵 科 ，郭 浩 （1.内蒙古自治区人民医院药学处，
呼和浩特 010017；2.内蒙古自治区基本药物监测与临床综合评价中心，呼和浩特 010017）
中图分类号 R95 文献标志码 A 文章编号 1001-0408（2024）23-2929-07
DOI 10.6039/j.issn.1001-0408.2024.23.15
摘 要 目的 分析内蒙古自治区公立医疗机构儿童药品使用情况，为全区儿童药品的合理应用以及儿童药品目录的完善提供参
考。方法 收集 2023 年内蒙古自治区全区各级公立医疗机构使用的儿童药品的通用名、规格以及剂型等信息，采用限定日剂量
（DDD）和排序比（B/A）分析法挖掘全区儿童药品的用药频度、日均费用以及药物经济性，并且统计全区公立医疗机构儿童药品剂
型、药物类别和用药衔接度。结果 2023年内蒙古自治区全区1 751家公立医疗机构配备的儿童药品品规数共计267个，包含12
个药物类别，剂型以颗粒剂、口服溶液剂和糖浆剂为主，各级公立医疗机构使用频率较高的药品主要为解热、镇痛及抗炎药（多为
中成药）和呼吸系统用药。三级、二级以及基层公立医疗机构儿童药品中用药频度最高的药品日均费用均较低，且大多数使用频
率较高的药品的B/A值均在1附近；但是部分药品的B/A值较高，可能存在过度使用的现象。基层公立医疗机构与二级、三级公立
医疗机构的药品衔接度均不足50%。结论 内蒙古自治区全区儿童药品涉及的药物类别较为全面，且社会效益和经济效益的同步
性良好，但是剂型较为单一且儿童专用品规和剂型较少。基层和二级公立医疗机构中成药的比例较高，用药风险不容忽视；基层
医疗机构儿童药品与上级医疗机构衔接性略差。
关键词 儿童用药；内蒙古自治区；药品剂型；用药频度；日均费用；B/A值；基本药物

Analysis of children’s drug use in Inner Mongolia based on big data of drug monitoring
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ZHAO Yufang ，LEI Wenpu ，LIU Zhien ，YANG Shengnan ，ZHANG Yanan ，ZHAO Ke ，GUO Hao 1， 2
（1. Dept. of Pharmacy， Inner Mongolia Autonomous Region People’s Hospital， Hohhot 010017， China；
2. Center for Essential Medicine Monitoring and Clinical Comprehensive Evaluation of Inner Mongolia
Autonomous Region， Hohhot 010017， China）
ABSTRACT OBJECTIVE To analyze the use of children’s drugs in public medical institutions in the Inner Mongolia
Autonomous Region， and provide some reference for the rational use of children’s drugs and the improvement of children’s drug
list in the whole region. METHODS The generic names， specifications， and dosage forms of children’s drugs were collected from
all levels of public medical institutions in the Inner Mongolia Autonomous Region in 2023. The method of defined daily dose
（DDD） and ranking ratio （B/A） were used to explore the frequency of drug use， daily average cost and cost-effectiveness of
children’s drugs in this region， and the dosage forms， category， and drug use convergence of children’s drugs in medical
institutions in the whole region. RESULTS In 2023， 1 751 public medical and health institutions in Inner Mongolia Autonomous
Region were equipped with 267 kinds of children’s drugs， including 12 drug categories. The main dosage forms were granules，
oral solutions， and syrups. The drugs that were frequently used in medical institutions at all levels were mainly antipyretic，
analgesic， anti-inflammatory drugs （mostly Chinese patent medicines）， and respiratory drugs. The daily average cost of children’s
drugs with the highest DDDs in tertiary， secondary， and primary public medical institutions was low， and the B/A value of most
drugs with higher DDDs was around 1. However， the B/A value of some drugs was high， which may lead to overuse. The drug use
convergence between primary public medical institutions and secondary/tertiary public medical institutions was less than 50%.
CONCLUSIONS The types of drugs involved in children’s drugs in Inner Mongolia Autonomous Region are comprehensive and
the social and economic benefits are in good synchronization， but the dosage form is single and there are few special rules and
dosage forms for children. The proportions of Chinese patent medicines in primary and secondary public medical institutions are
high， and the risk of drug use should be paid attention. The cohesion between children’s drugs in primary public medical
institutions and higher public medical institutions is slightly
Δ 基金项目 内蒙古自治区自然科学基金项目（No.2018LH08011）； poor.
内蒙古自治区人民医院院内基金项目（No.2020YN23） KEYWORDS children’s drug； Inner Mongolia Autonomous
＊ 第一作者 药 师 ，硕 士 。 研 究 方 向 ：医 院 药 学 。 E-mail：
Region； dosage form； DDD； DDC； B/A value； essential
zhaoyufangzs@163.com
medicine
# 通信作者 副主任药师，博士。研究方向：循证药学、药品临床综
合评价。E-mail：guohao851@163.com

中国药房 2024年第35卷第23期 China Pharmacy 2024 Vol. 35 No. 23 · 2929 ·