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子转录减少进而抑制炎症反应,改善患者呼吸功能,减                            [ 7 ]  SINGLA D,PARASHAR A,PANDEY V,et al. Compara‐
          少呼吸抑制的发生,从而保护大脑、心脏等器官,减少术                                tive  evaluation  of  dexmedetomidine  and  labetalol  for  at‐
                      [13]
          后谵妄的发生 。此外,DEX还能一定程度地减轻心脏                                tenuating  hemodynamic  stress  responses  during  laparo‐
          前后负荷,减少心输出量,对心肌细胞发挥保护作用,降                                scopic cholecystectomy in borderline hypertensive patients
                              [14]
          低心动过缓的发生风险 ,从而提高麻醉安全性。                                   [J]. Rev Esp Anestesiol Reanim,2019,66(4):181-188.
                                                              [ 8 ]  王伟,刘志刚,王正清,等. 右美托咪定镇静对老年心脏
              综上所述,DEX辅助全身麻醉可有效改善老年无痛
                                                                   术后患者血流动力学及谵妄的影响[J]. 中国中西医结合
          肠镜检查患者的血流动力学及认知功能,减少全麻用药
                                                                   急救杂志,2021,28(2):198-202.
          量,缩短患者苏醒时间,且安全性较好。
                                                                   WANG W,LIU Z G,WANG Z Q,et al. Effects of dexme‐
          参考文献
                                                                   detomidine  on  postoperative  cardiac  hemodynamics  and
          [ 1 ]  王荣华,张铨,陈明华. 右美托咪定复合依托咪酯在无痛                        delirium after cardiac surgery in elderly patients[J]. Chin J
               肠镜中的应用[J]. 海南医学,2017,28(17):2887-2889.              Integr Tradit West Med Intensive Crit Care,2021,28(2):
               WANG R H,ZHANG Q,CHEN M H. Application of dex‐      198-202.
               medetomidine combined with etomidate in painless ente-   [ 9 ]  张宏岩,岳海龙,马俊涛,等. 右美托咪定在老年胸腔镜
               roscopy[J]. Hainan Med J,2017,28(17):2887-2889.     肺叶切除手术中应用效果研究[J]. 中国煤炭工业医学杂
          [ 2 ]  SHIANI A,LIPKA S,LAI A,et al. Carbon dioxide versus   志,2023,26(4):374-377.
               room air insufflation during balloon-assisted enteroscopy:  ZHANG H Y,YUE H L,MA J T,et al. Clinical effect of
               a  systematic  review  with  meta-analysis[J].  Endosc  Int   dexmedetomidine in elderly patients undergoing thoraco‐
               Open,2017,5(1):E67-E75.                             scopic lobectomy[J]. Chin J Coal Ind Med,2023,26(4):
          [ 3 ]  罗佳艳,古学东,古小平,等. 右美托咪定联合芬太尼和                        374-377.
               丙泊酚在高血压患者无痛肠镜中的应用[J]. 西南医科大                    [10]  XU X F,CAO Y F,WU Y H,et al. Intranasal dexmedeto‐
               学学报,2018,41(4):334-338.                             midine in elderly patients (aged>65 years) during maxil‐
               LUO J Y,GU X D,GU X P,et al. Clinical application of   lofacial surgery:sedative properties and safety analysis[J].
               dexmedetomidine  combined  with  fentanyl  and  propofol   J Oral Maxillofac Surg,2022,80(3):443-455.
               for painless enteroscopy in patients with hypertension[J]. J   [11]  李冠军. 两种麻醉药物配伍对老年腹腔镜患者术后认知
               Southwest Med Univ,2018,41(4):334-338.              功能的影响[J]. 河北医学,2019,25(1):5-9.
          [ 4 ]  吴运香,柴小青,章蔚,等. LiDCOrapid监测液体治疗用                   LI G J. Two kinds of anesthesia methods on the postopera‐
               于老年患者无痛肠镜检查时的效果[J]. 临床麻醉学杂                          tive cognitive function of elderly patients with laparoscopy
               志,2021,37(9):969-971.                               [J]. Hebei Med,2019,25(1):5-9.
               WU  Y  X,CHAI  X  Q,ZHANG  W,et  al.  LiDCOrapid   [12]  CHILKOTI G T,KUMAR M,MOHTA M,et al. Compari‐
               monitoring  the  effect  of  liquid  therapy  on  painless  colo‐  son of postoperative analgesic efficacy of low-dose bolus
               noscopy in elderly patients[J]. J Clin Anesthesiol,2021,37  intravenous dexmedetomidine and intraperitoneal dexme‐
              (9):969-971.                                         detomidine with bupivacaine in patients undergoing lapa‐
          [ 5 ]  张伟,张卫. 脑电双频指数指导快通道麻醉在夹层动脉                         roscopic  cholecystectomy:a  randomized,controlled  trial
               瘤腔内隔绝术中的应用[J]. 临床麻醉学杂志,2011,27                      [J]. Indian J Anaesth,2019,63(2):106-113.
              (5):445-447.                                    [13]  王玉慧,温超,金锦花,等. 右美托咪定联合瑞芬太尼不
               ZHANG  W,ZHANG  W. Application  of  BIS  monitoring   同镇静深度对吸脂手术患者呼吸抑制的影响[J]. 临床和
               in  fast-track  anesthetic  patient  undergoing  endovascular   实验医学杂志,2021,20(9):999-1003.
               graft exclusion for aortic dissection[J]. J Clin Anesthesiol,  WANG Y H,WEN C,JIN J H,et al. Effects of dexmedeto‐
               2011,27(5):445-447.                                 midine combined with remifentanil for different sedation
          [ 6 ]  董心童,蔡兴涛,程翔. 右美托咪定对老年卵巢囊肿腹腔                        levels  on  respiratory  depression  in  patients  with  liposuc‐
               镜手术患者苏醒期躁动与术后认知功能的影响[J]. 海南                         tion[J]. J Clin Exp Med,2021,20(9):999-1003.
               医学,2019,30(9):1134-1136.                       [14]  WANG Q,CHEN C K,WANG L. Efficacy and safety of
               DONG X T,CAI X T,CHENG X. Effect of dexmedetomi‐    dexmedetomidine  in  maintaining  hemodynamic  stability
               dine  on  restlessness  and  postoperative  cognitive  function   in pediatric cardiac surgery:a systematic review and meta-
               in elderly patients with ovarian cysts during recovery from   analysis[J]. J Pediatr,2022,98(1):15-25.
               laparoscopic  surgery[J].  Hainan  Med  J,2019,30(9):        (收稿日期:2023-10-27  修回日期:2024-03-04)
               1134-1136.                                                                         (编辑:胡晓霖)


          · 1132 ·    China Pharmacy  2024 Vol. 35  No. 9                              中国药房  2024年第35卷第9期
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