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叙事药学在心血管药学门诊中的应用
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          叶小春 ,张 妍 ,祝 炜 ,高思远 ,张韶辉 (1.武汉市第一医院药学部,武汉 430022;2.武汉市第一医院心
          血管内科,武汉 430022;3.湖北科技学院药学院,湖北 咸宁 437100)
          中图分类号  R969.3      文献标志码  A      文章编号  1001-0408(2024)07-0872-05
          DOI  10.6039/j.issn.1001-0408.2024.07.18

          摘   要  目的  探讨临床药师通过叙事药学管理对心血管疾病合并负面情绪患者的用药依从性、负面情绪及生活质量的影响。
          方法  选取2023年2-8月武汉市第一医院心血管药学门诊就诊的49例有用药问题伴负面情绪的患者作为研究对象,在传统药学
          管理基础上,于患者就诊时及治疗2周时对患者加用叙事药学的模式进行管理。记录患者药物咨询相关问题、药物种类,对患者
          就诊时及管理1个月随访时的不良反应、血压及血脂、依从性、抑郁和焦虑状态、生活质量、患者满意度等变化进行比较。结果  采
          用叙事药学管理模式的49例患者涉及114个药物相关咨询问题;与就诊时比较,管理1个月后患者服药种类显著减少[4.00(2.00,
          6.00)种 vs. 3.00(1.50,5.00)种,P<0.05],不良反应发生率显著下降(32.65% vs. 2.04%,P<0.001),血压及血脂达标率显著升高
         (30.61% vs. 95.92%,P<0.001),患者用药依从性显著提高[(3.94±2.44)分 vs. (6.78±2.07)分,P<0.01],抑郁评分显著降低[3.00
         (2.00,4.50)分 vs. 2.00(0.00,3.00)分,P<0.001],焦虑评分显著降低[3.00(2.00,4.50)分 vs. 1.00(0.00,2.00)分,P<0.001],生活质
          量评分显著提高[22.00(19.00,22.00)分 vs. 23.00(23.00,24.50)分,P<0.01],满意度调查中患者的满意总占比稍有提高(91.84%
          vs. 97.96%,P>0.05)。结论  叙事药学应用于心血管药学门诊,能够提高患者依从性,减少药物不良反应,加强药物治疗有效性,
          避免药物相互作用,有效改善患者焦虑抑郁情绪,最终提高患者生活质量。
          关键词  叙事药学;心血管药学门诊;用药依从性;焦虑;抑郁;生活质量

          Application of narrative pharmacy in cardiovascular pharmacy clinic
          YE Xiaochun ,ZHANG Yan ,ZHU Wei ,GAO Siyuan ,ZHANG Shaohui(1.  Dept.  of  Pharmacy,  Wuhan  First
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          Hospital,  Wuhan  430022,  China;2.  Dept.  of  Cardiovascular  Medicine,  Wuhan  First  Hospital,  Wuhan  430022,
          China;3. School of Pharmacy, Hubei University of Science and Technology, Hubei Xianning 437100, China)
          ABSTRACT      OBJECTIVE  To  explore  the  effects  of  narrative  pharmacy  management  on  medication  compliance,  negative
          emotions, and quality of life in patients with cardiovascular disease complicated with negative emotions. METHODS A total of 49
          patients  with  drug  use  problems  and  negative  emotions  attending  the  cardiovascular  pharmacy  clinic  of Wuhan  First  Hospital  from
          February to August 2023 were selected as the study objects, narrative pharmacy model was applied for patient management during
          their  visits;  pharmaceutical  care  and  emotional  management  were  performed  after  2  weeks  of  treatment  and  a  follow-up  visit  was
          conducted  to  evaluate  and  record  the  management  effect  one  month  later.  RESULTS  Adopting  a  narrative  pharmacy  management
          model,  49  patients  were  involved  in  114  drug  related  consultation  questions.  Compared  with  the  visit,  after  one  month  of
          management,  the  number  of  medication  types  taken  by  patients  significantly  decreased  [4.00 (2.00,  6.00)  vs.  3.00 (1.50,  5.00),
          P<0.05], the incidence of adverse reactions significantly decreased (32.65% vs. 2.04%, P<0.001), the rate of blood pressure and
          lipid  compliance  significantly  increased (30.61%  vs.  95.92%,  P<0.001),  and  the  score  of  the  patient’s  medication  compliance
          significantly  improved  [(3.94±2.44)  vs. (6.78±2.07),  P<0.01]. The  depression  score  significantly  decreased  [3.00 (2.00,  4.50)
          vs.  2.00 (0.00,  3.00),  P<0.001],  the  anxiety  score  significantly  reduced  [3.00 (2.00,  4.50)  vs.  1.00 (0.00,  2.00),  P<0.001],
          quality  of  life  score  was  significantly  improved  [22.00 (19.00,  22.00)  vs.  23.00 (23.00,  24.50),  P<0.01].  In  the  satisfaction
          survey,  there  was  a  slight  increase  in  the  overall  satisfaction  proportion (91.84%  vs.  97.96%,  P>0.05).  CONCLUSIONS  The
          application of narrative pharmacy in cardiovascular pharmacy clinic can improve patient compliance, reduce adverse drug reactions,
          enhance the effectiveness of drug treatment, avoid drug interactions, effectively improve the anxiety and depression, and ultimately
          improve the quality of life.
          KEYWORDS     narrative pharmacy; cardiovascular pharmacy clinic; medication compliance; anxiety; depression; quality of life


              Δ 基金项目 湖北省卫生健康委临床重点(建设)专科项目(No.鄂                    在心内科就诊的患者中许多存在负面情绪,其中有
          卫通〔2019〕49号);武汉市卫生健康委中医药科研项目(No.WZ22Q35)            31.18% 存在抑郁情绪,有 30.46% 存在焦虑情绪 ,负面
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             *第一作者 主管药师,硕士。研究方向:临床药学。电话:027-
                                                              情绪使患者的治疗有效性、生活质量和临床预后均受到
          85332011。E-mail:xiaochunye@126.com
                                                              明显影响。研究资料表明,负面情绪(如抑郁、焦虑)是
              # 通信作者 副主任药师,博士。研究方向:临床药学。电话:027-
                                                                                                   [2]
          85332276。E-mail:53685340@qq.com                     心血管疾病及其预后不良的重要危险因素 ,增加急性
          · 872 ·    China Pharmacy  2024 Vol. 35  No. 7                               中国药房  2024年第35卷第7期
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