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叙事药学在心血管药学门诊中的应用
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叶小春 ,张 妍 ,祝 炜 ,高思远 ,张韶辉 (1.武汉市第一医院药学部,武汉 430022;2.武汉市第一医院心
血管内科,武汉 430022;3.湖北科技学院药学院,湖北 咸宁 437100)
中图分类号 R969.3 文献标志码 A 文章编号 1001-0408(2024)07-0872-05
DOI 10.6039/j.issn.1001-0408.2024.07.18
摘 要 目的 探讨临床药师通过叙事药学管理对心血管疾病合并负面情绪患者的用药依从性、负面情绪及生活质量的影响。
方法 选取2023年2-8月武汉市第一医院心血管药学门诊就诊的49例有用药问题伴负面情绪的患者作为研究对象,在传统药学
管理基础上,于患者就诊时及治疗2周时对患者加用叙事药学的模式进行管理。记录患者药物咨询相关问题、药物种类,对患者
就诊时及管理1个月随访时的不良反应、血压及血脂、依从性、抑郁和焦虑状态、生活质量、患者满意度等变化进行比较。结果 采
用叙事药学管理模式的49例患者涉及114个药物相关咨询问题;与就诊时比较,管理1个月后患者服药种类显著减少[4.00(2.00,
6.00)种 vs. 3.00(1.50,5.00)种,P<0.05],不良反应发生率显著下降(32.65% vs. 2.04%,P<0.001),血压及血脂达标率显著升高
(30.61% vs. 95.92%,P<0.001),患者用药依从性显著提高[(3.94±2.44)分 vs. (6.78±2.07)分,P<0.01],抑郁评分显著降低[3.00
(2.00,4.50)分 vs. 2.00(0.00,3.00)分,P<0.001],焦虑评分显著降低[3.00(2.00,4.50)分 vs. 1.00(0.00,2.00)分,P<0.001],生活质
量评分显著提高[22.00(19.00,22.00)分 vs. 23.00(23.00,24.50)分,P<0.01],满意度调查中患者的满意总占比稍有提高(91.84%
vs. 97.96%,P>0.05)。结论 叙事药学应用于心血管药学门诊,能够提高患者依从性,减少药物不良反应,加强药物治疗有效性,
避免药物相互作用,有效改善患者焦虑抑郁情绪,最终提高患者生活质量。
关键词 叙事药学;心血管药学门诊;用药依从性;焦虑;抑郁;生活质量
Application of narrative pharmacy in cardiovascular pharmacy clinic
YE Xiaochun ,ZHANG Yan ,ZHU Wei ,GAO Siyuan ,ZHANG Shaohui(1. Dept. of Pharmacy, Wuhan First
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Hospital, Wuhan 430022, China;2. Dept. of Cardiovascular Medicine, Wuhan First Hospital, Wuhan 430022,
China;3. School of Pharmacy, Hubei University of Science and Technology, Hubei Xianning 437100, China)
ABSTRACT OBJECTIVE To explore the effects of narrative pharmacy management on medication compliance, negative
emotions, and quality of life in patients with cardiovascular disease complicated with negative emotions. METHODS A total of 49
patients with drug use problems and negative emotions attending the cardiovascular pharmacy clinic of Wuhan First Hospital from
February to August 2023 were selected as the study objects, narrative pharmacy model was applied for patient management during
their visits; pharmaceutical care and emotional management were performed after 2 weeks of treatment and a follow-up visit was
conducted to evaluate and record the management effect one month later. RESULTS Adopting a narrative pharmacy management
model, 49 patients were involved in 114 drug related consultation questions. Compared with the visit, after one month of
management, the number of medication types taken by patients significantly decreased [4.00 (2.00, 6.00) vs. 3.00 (1.50, 5.00),
P<0.05], the incidence of adverse reactions significantly decreased (32.65% vs. 2.04%, P<0.001), the rate of blood pressure and
lipid compliance significantly increased (30.61% vs. 95.92%, P<0.001), and the score of the patient’s medication compliance
significantly improved [(3.94±2.44) vs. (6.78±2.07), P<0.01]. The depression score significantly decreased [3.00 (2.00, 4.50)
vs. 2.00 (0.00, 3.00), P<0.001], the anxiety score significantly reduced [3.00 (2.00, 4.50) vs. 1.00 (0.00, 2.00), P<0.001],
quality of life score was significantly improved [22.00 (19.00, 22.00) vs. 23.00 (23.00, 24.50), P<0.01]. In the satisfaction
survey, there was a slight increase in the overall satisfaction proportion (91.84% vs. 97.96%, P>0.05). CONCLUSIONS The
application of narrative pharmacy in cardiovascular pharmacy clinic can improve patient compliance, reduce adverse drug reactions,
enhance the effectiveness of drug treatment, avoid drug interactions, effectively improve the anxiety and depression, and ultimately
improve the quality of life.
KEYWORDS narrative pharmacy; cardiovascular pharmacy clinic; medication compliance; anxiety; depression; quality of life
Δ 基金项目 湖北省卫生健康委临床重点(建设)专科项目(No.鄂 在心内科就诊的患者中许多存在负面情绪,其中有
卫通〔2019〕49号);武汉市卫生健康委中医药科研项目(No.WZ22Q35) 31.18% 存在抑郁情绪,有 30.46% 存在焦虑情绪 ,负面
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*第一作者 主管药师,硕士。研究方向:临床药学。电话:027-
情绪使患者的治疗有效性、生活质量和临床预后均受到
85332011。E-mail:xiaochunye@126.com
明显影响。研究资料表明,负面情绪(如抑郁、焦虑)是
# 通信作者 副主任药师,博士。研究方向:临床药学。电话:027-
[2]
85332276。E-mail:53685340@qq.com 心血管疾病及其预后不良的重要危险因素 ,增加急性
· 872 · China Pharmacy 2024 Vol. 35 No. 7 中国药房 2024年第35卷第7期