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·药师与药学服务·


          临床药师构建肺诺卡菌病会诊思维导图的临床药学实践
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          邓体瑛 ,胡志敏 ,徐 清 ,张韶辉 ,李璐璐 ,郭 珩 ,胡 磊 ,陈 凡(1.武汉市第一医院药学部临床药学
          室,武汉 430022;2. 武汉市第一医院检验科微生物室,武汉 430022;3. 武汉市第一医院呼吸内科,武汉
          430022)
          中图分类号  R95;R978      文献标志码  A      文章编号  1001-0408(2023)15-1899-05
          DOI  10.6039/j.issn.1001-0408.2023.15.20
          摘  要  目的  探讨临床药师构建肺诺卡菌病会诊思维导图并应用于临床实践,为促进临床正确遴选诺卡菌病治疗用药并保障药
          物安全性及疗效提供参考。方法  收集2017年1月-2022年4月我院肺诺卡菌感染患者7例,依据循证医学证据,针对诺卡菌菌
          种不同药敏性差异大和一线药物复方磺胺甲噁唑不良反应多的难点,构建会诊思维导图(主要包括了解病史、确定感染菌、明确危
          险因素、制定治疗方案、治疗评估等),制定7例肺诺卡菌感染患者的治疗方案,并进行全程药学监护。结果  结合思维导图,根据
          诺卡菌菌种的不同、有无药敏结果、患者的过敏史等予以不同的抗菌药物联合方案,其中4例均联合了亚胺培南西司他丁治疗,对
          长期使用复方磺胺甲噁唑、利奈唑胺的患者进行全程药学监护,并及时处理了药物不良反应。结论  临床药师将肺诺卡菌病会
          诊思维导图运用到住院患者治疗过程中,利用药学专业优势,参与临床药物治疗,在临床治疗团队中发挥了积极作用,促进了患者
          合理用药。
          关键词  肺诺卡菌病;临床药师;思维导图;药学实践;会诊

          Clinical  pharmaceutical  practice  of  constructing  mind  map  by  clinical  pharmacists  for  the  consultation  of
          pulmonary nocardiosis
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          DENG Tiying ,HU Zhimin ,XU Qing ,ZHANG Shaohui ,LI Lulu ,GUO Heng ,HU Lei ,CHEN Fan
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         (1. Clinical Pharmacy Support, Pharmacy Department, Wuhan Municipal First Hospital, Wuhan 430022, China;
          2. Microbiology Lab, Clinical Laboratory Department, Wuhan Municipal First Hospital, Wuhan 430022, China;
          3. Dept. of Respiratory Medicine, Wuhan Municipal First Hospital, Wuhan 430022, China)
          ABSTRACT   OBJECTIVE  To  explore  the  construction  of  mind  map  by  clinical  pharmacists  for  the  consultation  of  pulmonary
          nocardiosis  and  its  application  in  clinical  practice,  and  to  provide  reference  for  promoting  the  correct  selection  of  nocardiosis
          treatment  drugs  in  clinical  practice  and  ensuring  drug  safety  and  efficacy.  METHODS  A  total  of  7  patients  with  Nocardia
          pulmonary  infection  from  January  2017  to  April  2022  in  our  hospital  were  collected.  Based  on  evidence-based  medicine,  a
          consultation mind map (mainly including understanding the medical history, identifying infectious bacteria, identifying risk factors,
          developing  treatment  plans,  and  conducting  evaluations)  was  constructed  to  address  the  difficulties  of  large  differences  in  drug
          sensitivity  among  different  strains  of  Nocardia  and  numerous  adverse  reactions  of  Compound  sulfamethoxazole  as  a  first-line  drug.
          The treatment plan was developed for 7 patients with pulmonary nocardiosis, and whole-process pharmaceutical care was provided.
          RESULTS  Combined  with  the  mind  map,  different  antibiotic  combination  regimens  were  given  according  to  the  drug  sensitivity
          results  of  Nocardia,  the  different  species  of  Nocardia,  and  the  patient’s  allergy  history. Among  them,  4  cases  were  treated  with
          imipenem cilastatin, the patients receiving Compound sulfamethoxazole and linezolid for a long time were given full pharmaceutical
                                                             care,  and  the  adverse  drug  reactions  were  timely  treated.
             Δ 基金项目 国家中医药管理局“十二五”中医重点专科协作项目                  CONCLUSIONS  Clinical  pharmacists  apply  the  consultation
         (No.国中医办医政函〔2012〕123号);湖北省三级医院临床药学重点专               mind  map  of  pulmonary  nocardiosis  to  the  treatment  of
          科项目(No. 鄂卫通〔2019〕125 号);武汉市卫生健康委医学科研项目             inpatients,  take  advantage  of  pharmacy,  participate  in  clinical
         (No.WH21C21)                                        drug  therapy,  and  really  play  a  role  in  the  clinical  treatment
             *第一作者 副主任药师,硕士。研究方向:临床药学。电话:027-
                                                             team so as to promote rational drug use.
          85332276。E-mail:oldcat305@163.com
             # 通信作者 副主任技师,博士。研究方向:感染性疾病的实验室                  KEYWORDS     pulmonary  nocardiosis;  clinical  pharmacists;
          诊断。电话:027-85332629。E-mail:mycohu@163.com           mind map; pharmacy practice; consultation


          中国药房  2023年第34卷第15期                                              China Pharmacy  2023 Vol. 34  No. 15    · 1899 ·
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