Page 120 - 《中国药房》2022年12期
P. 120

fication of genetic variations of the human organic cation  Curr Pharm Des,2017,23(17):2532-2550.
             transporter hOCT1 and their functional consequences[J].  [33]  HE L,WONDISFORD F E. Metformin action:concentra-
             Pharmacogenetics,2002,12(8):591-595.                tions matter[J]. Cell Metab,2015,21(2):159-162.
        [20]  ITODA M,SAITO Y,MAEKAWA K,et al. Seven novel  [34]  XIA L,ENGEL K,ZHOU M Y,et al. Membrane localiza-
             single nucleotide polymorphisms in the human SLC22A1  tion and pH-dependent transport of a newly cloned orga-
             gene encoding organic cation transporter 1(OCT1)[J].  nic cation transporter(PMAT)in kidney cells[J]. Am J
             Drug Metab Pharmacokinet,2004,19(4):308-312.        Physiol Renal Physiol,2007,292(2):F682-F690.
        [21]  BECKER M L,VISSER L E,VAN SCHAIK R H N,et al.  [35]  BACHMAKOV I,GLAESER H,FROMM M F,et al. In-
             Interaction between polymorphisms in the OCT1 and   teraction of oral antidiabetic drugs with hepatic uptake
             MATE1 transporter and metformin response[J]. Pharmaco-  transporters:focus on organic anion transporting polypep-
             genet Genomics,2010,20(1):38-44.                    tides and organic cation transporter 1[J]. Diabetes,2008,
        [22]  WRÓBEL M P,MAREK B,KAJDANIUK D,et al. Met-         57(6):1463-1469.
             formin:a new old drug[J]. Endokrynol Pol,2017,68(4):  [36]  DING Y,JIA Y Y,SONG Y,et al. The effect of lansopra-
             482-496.                                            zole,an OCT inhibitor,on metformin pharmacokinetics in
        [23]  ITO S,KUSUHARA H,KUROIWA Y,et al. Potent and       healthy subjects [J]. Eur J Clin Pharmacol,2014,70(2):
             specific inhibition of mMate1-mediated efflux of type Ⅰ  141-146.
             organic cations in the liver and kidney by pyrimethamine[J].  [37]  NIES A T,HOFMANN U,RESCH C,et al. Proton pump
             J Pharmacol Exp Ther,2010,333(1):341-350.           inhibitors inhibit metformin uptake by organic cation
        [24]  STOCKER S L,MORRISSEY K M,YEE S W,et al. The       transporters(OCTs)[J]. PLoS One,2011,6(7):e22163.
             effect of novel promoter variants in MATE1 and MATE2  [38]  KIM A,CHUNG I,YOON S H,et al. Effects of proton
             on the pharmacokinetics and pharmacodynamics of met-  pump inhibitors on metformin pharmacokinetics and phar-
             formin[J]. Clin Pharmacol Ther,2013,93(2):186-194.  macodynamics[J]. Drug Metab Dispos,2014,42(7):
        [25]  CHOI J H,YEE S W,RAMIREZ A H,et al. A common       1174-1179.
             5′-UTR variant in MATE2-K is associated with poor  [39]  STAUD F,CERVENY L,AHMADIMOGHADDAM D,
             response to metformin[J]. Clin Pharmacol Ther,2011,90  et al. Multidrug and toxin extrusion proteins(MATE/
             (5):674-684.                                        SLC47);role in pharmacokinetics[J]. Int J Biochem Cell
        [26]  TAKANE H,SHIKATA E,OTSUBO K,et al. Polymor-        Biol,2013,45(9):2007-2011.
             phism in human organic cation transporters and metfor-  [40]  MISAKA S,KNOP J,SINGER K,et al. The nonmetabo-
             min action[J]. Pharmacogenomics,2008,9(4):415-422.  lized β-blocker nadolol is a substrate of OCT1,OCT2,
        [27]  SONG I S,SHIN H J,SHIM E J,et al. Genetic variants of  MATE1,MATE2-K,and P-glycoprotein,but not of
             the organic cation transporter 2 influence the disposition  OATP1B1 and OATP1B3[J]. Mol Pharm,2016,13(2):
             of metformin[J]. Clin Pharmacol Ther,2008,84(5):559-  512-519.
             562.                                           [41]  SOMOGYI A,STOCKLEY C,KEAL J,et al. Reduction
        [28]  WANG Z J,YIN O Q P,TOMLINSON B,et al. OCT2         of metformin renal tubular secretion by cimetidine in
             polymorphisms and in-vivo renal functional consequence:  man[J]. Br J Clin Pharmacol,1987,23(5):545-551.
             studies with metformin and cimetidine[J]. Pharmacogenet  [42]  CHO S K,CHUNG J Y. The MATE1 rs2289669 polymor-
             Genomics,2008,18(7):637-645.                        phism affects the renal clearance of metformin following
        [29]  玛依拉·艾则孜.维吾尔族 SLC22A2 多态性及 rs316019                 ranitidine treatment[J]. Int J Clin Pharmacol Ther,2016,
             突变对二甲双胍药代学、药效学的影响[D].乌鲁木齐:新                         54(4):253-262.
             疆医科大学,2019.                                    [43]  HIBMA J E,ZUR A A,CASTRO R A,et al. The effect of
        [30]  MOON S J,OH J,LEE S H,et al. Effect of plasma mem-  famotidine,a MATE1-selective inhibitor,on the pharma-
             brane monoamine transporter genetic variants on pharma-  cokinetics and pharmacodynamics of metformin[J]. Clin
             cokinetics of metformin in humans[J]. Transl Clin Pharma-  Pharmacokinet,2016,55(6):711-721.
             col,2018,26(2):79-85.                          [44]  GRÜN B,KIESSLING M K,BURHENNE J,et al. Trime-
        [31]  CHOI M K,SONG I S. Genetic variants of organic cation  thoprim-metformin interaction and its genetic modulation
             transporter 1(OCT1)and OCT2 significantly reduce lami-  by OCT2 and MATE1 transporters[J]. Br J Clin Pharma-
             vudine uptake[J]. Biopharm Drug Dispos,2012,33(3):  col,2013,76(5):787-796.
             170-178.                                       [45]  JAYASAGAR G,KRISHNAKUMAR M,CHANDRASEKHAR
        [32]  MARKOWICZ-PIASECKA M,HUTTUNEN K M,                 K,et al. Effect of cephalexin on the pharmacokinetics of
             MATEUSIAK L,et al. Is metformin a perfect drug? Up-  metformin in healthy human volunteers[J]. Drug Metabol
             dates in pharmacokinetics and pharmacodynamics[J].  Drug Interact,2002,19(1):41-48.


        ·1518 ·  China Pharmacy 2022 Vol. 33 No. 12                                 中国药房    2022年第33卷第12期
   115   116   117   118   119   120   121   122   123   124   125