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是后续长期随访研究中需要完善的内容。本研究目前 diol,2018,258:192-198.
仅对目标人群进行了6个月的随访,之后将继续随访观 [10] ISHII M,KAIKITA K,SATO K,et al. Cardioprotective
察至用药后 3 年,以进一步明确 ARNI 类药物对目标人 effects of LCZ696(sacubitril/valsartan)after experimen-
群的长期治疗效果。 tal acute myocardial infarction[J]. JACC Basic Transl Sci,
综上所述,针对 AAMI 合并急性心功能不全患者, 2017,2(6):655-668.
沙库巴曲缬沙坦钠较依那普利可以带来更多的临床获 [11] 陈春望,钱文浩,丁浩,等.沙库巴曲缬沙坦对急性前壁心
益,包括明显改善患者的心功能(尤其是左心室收缩功 肌梗死急诊 PCI 术后合并心功能不全患者近期预后的
影响[J].现代生物医学进展,2019,19(19):3720-3725.
能)、减轻患者心肌细胞的炎症反应并保护心肌细胞,从
[12] 李锦爽,周浩,王万虹,等.沙库巴曲缬沙坦对急性ST段
而改善患者的短期预后。
抬高型心肌梗死患者左室重构的影响[J].中国新药与临
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·2894 · China Pharmacy 2021 Vol. 32 No. 23 中国药房 2021年第32卷第23期