Page 131 - 2021年17期
P. 131
结肠癌细胞 SW480 凋亡的影响[D].锦州:锦州医科大 suppresses metastasis mediated by reactive oxygen spe-
学,2019. cies(ROS)via focal adhesion kinase(FAK)in breast
[37] QIN S,LI J,SI Y,et al. Cucurbitacin B induces inhibitory cancer MDA-MB-231 cells[J]. Chin J Nat Med,2018,16
effects via CIP2A/PP2A/Akt pathway in glioblastoma (1):10-19.
multiforme[J]. Mol Carcinog,2018,57(6):687-699. [50] PROMKAN M,DAKENG S,CHAKRABARTY S,et al.
[38] KLUNGSAENG S,KUKONGVIRIYAPAN V,PRAWAN The effectiveness of cucurbitacin B in BRCA1 defective
A,et al. Cucurbitacin B induces mitochondrial-mediated breast cancer cells[J]. PloS One,2013,8(2):e55732.
apoptosis pathway in cholangiocarcinoma cells via sup- [51] 梁菁.葫芦素 B 通过改变细胞生物力学性质抑制乳腺癌
pressing focal adhesion kinase signaling[J]. Naunyn 细胞迁移和侵袭[D].天津:天津医科大学,2019.
Schmiedebergs Arch Pharmacol,2019,392(3):271-278. [52] ZANOTELLI M R,REINHART-KING C A. Mechanical
[39] DAKENG S,DUANGMANO S,JIRATCHARIYAKUL W, forces in tumor angiogenesis[J]. Adv Exp Med Bio,2018,
et al. Inhibition of Wnt signaling by cucurbitacin B in 1092:91-112.
breast cancer cells:reduction of Wnt-associated proteins [53] MACKLIN P S,MCAULIFFE J,PUGH C W,et al. Hy-
and reduced translocation of galectin-3-mediated β-catenin poxia and HIF pathway in cancer and the placenta[J]. Pla-
to the nucleus[J]. J Cell Biochem,2012,113(1):49-60. centa,2017,56:8-13.
[40] BAKAR F. Cucurbitacin B enhances the anticancer effect [54] PIAO X M,GAO F,ZHU J X,et al. Cucurbitacin B inhi-
of imatinib mesylate through inhibition of MMP-2 expres- bits tumor angiogenesis by triggering the mitochondrial
sion in MCF-7 and SW480 tumor cell lines[J]. Anticancer signaling pathway in endothelial cells[J]. Int J Mol Med,
Agents Med Chem,2016,16(6):747-754. 2018,42(2):1018-1025.
[41] 张萌,边志刚,何平.葫芦素B对人胃癌BGC-823细胞增 [55] SINHA S,KHAN S,SHUKLA S,et al. Cucurbitacin B in-
殖及凋亡的影响[J].实用药物与临床,2016,19(5):548- hibits breast cancer metastasis and angiogenesis through
552. VEGF-mediated suppression of FAK/MMP-9 signaling
[42] ZHANG Z R,GAO M X,YANG K. Cucurbitacin B inhi- axis[J]. Int J Biochem Cell Biol,2016,77(Pt A):41-56.
bits cell proliferation and induces apoptosis in human os- [56] TOUIHRI-BARAKATI I,KALLECH-ZIRI O,AYADI W,
teosarcoma cells via modulation of the JAK2/STAT3 and et al. Cucurbitacin B purified from Ecballium elaterium
MAPK pathways[J]. Exp Ther Med,2017,14(1):805- (L.)A. Rich from Tunisia inhibits α5β1 integrin-mediated
812. adhesion,migration,proliferation of human glioblastoma
[43] 张萌,边志刚,张毅,等.葫芦素B诱导G2/M期阻滞抑制 cell line and angiogenesis[J]. Eur J Pharmacol,2017,797:
人前列腺癌DU145细胞增殖并诱导细胞凋亡研究[J].中 153-161.
国医刊,2016,51(2):63-67. [57] HALL A. The cytoskeleton and cancer[J]. Cancer Metastasis
[44] CHAI Y,XIANG K,WU Y,et al. Cucurbitacin B inhibits Rev,2009,28(1/2):5-14.
the Hippo-YAP signaling pathway and exerts anticancer [58] LIANG J,ZHANG X L,YUAN J W,et al. Cucurbitacin
activity in colorectal cancer cells[J]. Med Sci Monit, B inhibits the migration and invasion of breast cancer
2018,24:9251-9258. cells by altering the biomechanical properties of cells[J].
[45] 周彤,杨书胜,罗明洲,等.葫芦素B通过抑制Hippo-YAP Phytother Res,2019,33(3):618-630.
通路抑制结肠癌细胞转移的机制研究[J].湖北医药学院 [59] WAKIMOTO N,YIN D,O’KELLY J,et al. Cucurbitacin
学报,2020,39(1):16-21,105. B has a potent antiproliferative effect on breast cancer
[46] SHUKLA S,SINHA S,KHAN S,et al. Cucurbitacin B in- cells in vitro and in vivo[J]. Cancer Sci,2008,99(9):
hibits the stemness and metastatic abilities of NSCLC via 1793-1797.
downregulation of canonical Wnt/β-catenin signaling [60] YIN D,WAKIMOTO N,XING H,et al. Cucurbitacin B
axis[J]. Sci Rep,2016,6:21860. markedly inhibits growth and rapidly affects the cytoskele-
[47] 喻婷婷,徐丽,董超群,等.葫芦素 B 抑制骨肉瘤 143B 细 ton in glioblastoma multiforme[J]. Int J Cancer,2008,123
胞的增殖和侵袭并促进其凋亡[J].肿瘤,2019,39(4): (6):1364-1375.
249-258. [61] KAUSAR H,MUNAGALA R,BANSAL S S,et al. Cu-
[48] GUPTA P,SRIVASTAVA S K. HER2 mediated de novo curbitacin B potently suppresses non-small-cell lung can-
production of TGFβ leads to SNAIL driven epithelial-to- cer growth:identification of intracellular thiols as critical
mesenchymal transition and metastasis of breast cancer[J]. targets[J]. Cancer Lett,2013,332(1):35-45.
Mol Oncol,2014,8(8):1532-1547. [62] YANG T,LIU J,YANG M,et al. Cucurbitacin B exerts an-
[49] LUO W W,ZHAO W W,LU J J,et al. Cucurbitacin B ti-cancer activities in human multiple myeloma cells in vi-
中国药房 2021年第32卷第17期 China Pharmacy 2021 Vol. 32 No. 17 ·2169 ·