Page 121 - 2021年14期
P. 121

2018,38(4):639-654.                                set of effect and impact on health-related quality of life,
        [ 8 ]  TAN L D,BRATT J M,GODOR D,et al. Benralizumab:a  exacerbation rate,lung function,and nasal polyposis
             unique IL-5 inhibitor for severe asthma[J]. J Asthma  symptoms for patients with severe eosinophilic asthma
             Allergy,2016,9(4):71-81.                           treated with benralizumab(ANDHI):a randomised,con-
        [ 9 ]  LAVIOLETTE M,GOSSAGE D L,GAUVREAU G,et al.       trolled,phase 3b trial[J]. Lancet Respir Med,2021,9(3):
             Effects of benralizumab on airway eosinophils in asthma-  260-274.
             tic patients with sputum eosinophilia[J]. J Allergy Clin  [19]  CHUNG K F,WENZEL S E,BROZEK J L,et al. Interna-
             Immunol,2013,132(5):1086-1096.                     tional ERS/ATS guidelines on definition,evaluation and
        [10]  CASTRO M,WENZEL S E,BLEECKER E R,et al. Ben-      treatment of severe asthma[J]. Eur Respir J,2014,43(2):
             ralizumab,an anti-interleukin 5 receptor α monoclonal an-  343-373.
             tibody,versus placebo for uncontrolled eosinophilic asth-  [20]  HAYASHINO Y,NOGUCHI Y,FUKUI T. Systematic
             ma:a phase 2b randomised dose-ranging study[J]. Lancet  evaluation and comparison of statistical tests for publica-
             Respir Med,2014,2(11):879-890.                     tion bias[J]. J Epidemiol,2005,15(6):235-243.
        [11]  NOWAK R M,PARKER J M,SILVERMAN R A,et al.    [21]  KASSA G M. Mother-to-child transmission of HIV infec-
             Arandomized trial of benralizumab,an antiinterleukin 5  tion and its associated factors in Ethiopia:a systematic re-
             receptor α monoclonal antibody,after acute asthma[J].  view and meta-analysis[J]. BMC Infect Dis,2018,18(1):
             Am J Emerg Med,2015,33(1):14-20.                   1-9.
                                                           [22]  王吉耀.循证医学与临床实践[M]. 4 版.北京:科学出版
        [12]  PARK H S,KIM M K,IMAI N,et al. A phase 2a study of
                                                                社,2019:122.
             benralizumab for patients with eosinophilic asthma in
                                                           [23]  WANG B,YAN L,HUTMACHER M,et al. Exposure-re-
             South Korea and Japan[J]. Int Arch Allergy Immunol,
                                                                sponse analysis for determination of benralizumab optimal
             2016,169(3):135-45.
                                                                dosing regimen in adults with asthma[J]. Am J Respir Crit
        [13]  FITZGERALD J M,BLEECKER E R,NAIR P,et al. Ben-
                                                                Care Med,2014,189(9):A1324.
             ralizumab,an anti-interleukin-5 receptor α monoclonal an-
                                                           [24]  PAPI A,BLASI F,CANONICA G W,et al. Treatment
             tibody,as add-on treatment for patients with severe,un-
                                                                strategies for asthma:reshaping the concept of asthma
             controlled,eosinophilic asthma (CALIMA) :a ran-
                                                                management[J]. Allergy Asthma ClinImmunol,2020,16
             domised,double-blind,placebo-controlled phase 3 trial[J].
                                                                (3):75-85.
             Lancet,2016,388(10056):2128-2141.
                                                           [25]  KITCH B T,PALTIEL A D,KUNTZ K M,et al. A single
        [14]  BLEECKER E R,FITZGERALD J M,CHANEZ P,et al.
                                                                measure of FEV1 is associated with risk of asthma attacks
             Efficacy and safety of benralizumab for patients with se-
                                                                in long-term follow-up[J]. Chest,2004,126(6):1875-
             vere asthma uncontrolled with high-dosage inhaled corti-
                                                                1882.
             costeroids and long-acting β 2-agonists(SIROCCO):a ran-
                                                           [26]  JUNIPER E F,SVENSSON K,MORK A C,et al. Mea-
             domised,multicentre,placebo-controlled phase 3 trial[J].
                                                                surement properties and interpretation of three shortened
             Lancet,2016,388(10056):2115-2127.
                                                                versions of the asthma control questionnaire[J]. Respir
        [15]  NAIR P,WENZEL S,RABE K F,et al. Oral glucocorti-
                                                                Med,2005,99(5):553-558.
             coid-sparing effect of benralizumab in severe asthma[J].
                                                           [27]  齐军,吴倩,李森,等.哮喘控制问卷与哮喘生命质量问卷
             N Engl J Med,2017,376(25):2448-2458.
                                                                在哮喘患者中的应用价值研究[J].国际呼吸杂志,2014,
        [16]  FERGUSON G T,FITZGERALD J M,BLEECKER E R,         34(3):174-176.
             et al. Benralizumab for patients with mild to moderate,
                                                           [28]  TIAN B P,ZHANG G S,LOU J,et al. Efficacy and safety
             persistent asthma(BISE):a randomised,double-blind,pla-  of benralizumab for eosinophilic asthma:a systematic re-
             cebo-controlled,phase 3 trial[J]. Lancet Respir Med,  view and meta-analysis of randomized controlled trials[J].
             2017,5(7):568-576.                                 J Asthma,2018,55(9):956-965.
        [17]  PANETTIERI R A,Jr,WELTE T,SHENOY K V,et al.  [29]  BUSSE W W,BLEECKER E R,FITZGERALD J M,et al.
             Onset of effect,changes in airflow obstruction and lung  Long-term safety and efficacy of benralizumab in patients
             volume,and health-related quality of life improvements  with severe,uncontrolled asthma:1-year results from the
             with benralizumab for patients with severe eosinophilic  BORA phase 3 extension trial[J]. Lancet Respir Med,
             asthma:phase Ⅲb randomized,controlled trial(SOLANA)  2019,7(1):46-59.
             [J]. J Asthma Allergy,2020,13(2):115-126.                    (收稿日期:2021-02-01  修回日期:2021-05-15)
        [18]  HARRISON T W,CHANEZ P,MENZELLA F,et al. On-                                       (编辑:林    静)



        中国药房    2021年第32卷第14期                                            China Pharmacy 2021 Vol. 32 No. 14  ·1775 ·
   116   117   118   119   120   121   122   123   124   125   126