Page 133 - 202012
P. 133

tor receptor-2 inhibitor YN968D1 in patients with ad-  2004,28(10):451-455.
             vanced malignancies[J]. BMC Cancer,2010. DOI:10.1186/  [14]  LEE JE,KIM KL,KIM D,et al. Apatinib-loaded nanopar-
             1471-2407-10-529.                                  ticles suppress vascular endothelial growth factor-induced
        [ 2 ]  TIAN S,QUAN HT,XIE CY,et al. YN968D1 is a nov-   angiogenesis and experimental corneal neovasculariza-
             el and selective inhibitor of vascular endothelial growth  tion[J]. Int J Nanomed,2017. DOI:10.2147/IJN.S135133.
             factor receptor-2 tyrosine kinase with potent activity in vi-  [15]  OWEN SC,CHAN DPY,SHOICHET MS,Polymeric mi-
             tro and in vivo[J]. Cancer Sci,2011,102(7):1374-1380.  celle stability[J]. Nano Today,2012,7(1):53-65.
        [ 3 ]  YANG CX,QIN SK. Apatinib targets both tumor and en-  [16]  YONCHEVA K,CALLEJA P,AGÜEROS M,et al. Stabi-
             dothelial cells in hepatocellular carcinoma[J]. Cancer  lized micelles as delivery vehicles for paclitaxel[J]. Int J
             Med,2018,7(9):4570-4583.                           Pharm,2012,436(1/2):258-264.
        [ 4 ]  HAN ZH,HE ZM,WANG CY,et al.The effect of apatinib  [17]  NEDERBERG F,APPEL E,TAN JPK,et al. Simple ap-
             in the treatment of sorafenib resistant metastatic hepatocel-  proach to stabilized micelles employing miktoarm terpoly-
             lular carcinoma:a case report[J]. Medicine:Baltimore,  mers and stereocomplexes with application in paclitaxel
             2018. DOI:10.1097/MD.0000000000013388.             delivery[J]. Biomacromolecules,2009,10(6):1460-1468.
        [ 5 ]  ZHANG L,SHI MQ,HUANG C,et al. A phase Ⅱ,multi-  [18]  POOL R,BOLHUIS PG,The influence of micelle forma-
             center,placebo-controlled trial of apatinib in patients with  tion on the stability of colloid surfactant mixtures[J]. Phys
             advanced nonsquamous non-small cell lung cancer(NSCLC)  Chem Chem Phys,2010,12(44):14789-14797.
             after two previous treatment regimens[J]. J Clin Oncol,  [19]  DAI YX,WANG S,SHI WB,et al. pH-responsive car-
             2012. DOI:10.1200/jco.2012.30.15_suppl.7548.       boxymethyl chitosan-derived micelles as apatinib carriers
        [ 6 ]  HU XC,CAO J,HU WW,et al. Multicenter phase Ⅱ stu-  for effective anti-angiogenesis activity:preparation and in
             dy of apatinib in non-triple-negative metastatic breast can-  vitro evaluation[J]. Carbohydr Polym,2017. DOI:10.1016/
             cer[J]. BMC Cancer,2014. DOI:10.1186/1471-2407-14-  j.carbpol.2017.08.011.
             820.                                          [20]  WEI X,LIU LQ,GUO X,et al. Light-activated ROS-re-
        [ 7 ]  孙培培,张龙,张泰,等.单药阿帕替尼治疗二线及二线以                       sponsive nanoplatformcodelivering apatinib and doxorubi-
             上化疗失败的晚期大肠癌患者疗效分析[J].临床肿瘤学                         cin forenhanced chemo-photodynamic therapy ofmulti-
             杂志,2017,22(7):646-649.                             drug-resistant tumors[J]. ACS Appl Mater Inter,2018,10
        [ 8 ]  QIN SK. Apatinib in Chinese patients with advanced hepa-  (21):17672-17684.
             tocellular carcinoma:a phase Ⅱ randomized,open-label  [21]  DANHIER F,FERON O,PRÉAT V. To exploit the tumor
             trial[J]. J Clin Oncol,2014. DOI:10.1200/jco.2014.32.15_  microenvironment:passive and active tumor targeting of
             suppl.4019.                                        nanocarriers for anti-cancer drug delivery[J]. J Control Re-
        [ 9 ]  MI YJ,LIANG YJ,HUANG HB,et al. Apatinib(YN968D1)  lease,2010,148(2):135-146.
             reverses multidrug resistance by inhibiting the efflux func-  [22]  HU YZ,WU C,ZHU CH,et al. Enhanced uptake and im-
             tion of multiple ATP-binding cassette transporters[J]. Can-  proved anti-tumor efficacy of doxorubicin loaded fibrin
             cer Res,2010,70(20):7981-7991.                     gel with liposomal apatinib in colorectal cancer[J]. Int J
        [10]  HALASZ K,KELLY SJ,IQBAL MT,et al. Utilization of  Pharm,2018,552(1/2):319-327.
             apatinib-loaded nanoparticles for the treatment of ocular  [23]  YU T,WU C,ZHU CH,et al. Oral Administration of lipo-
             neovascularization[J]. Curr Drug Deliv,2019,16(2):  some-apatinib and locally delivery of docetaxel/MPEG-
             153-163.                                           PCL by fibrin glue synergistically improve therapeutic ef-
        [11]  JEONG JH,NGUYEN HK,LEE JE,et al. Therapeutic ef-  fect in colorectal cancer[J]. J Biomed Nanotechnol,2018,
             fect of apatinib-loaded nanoparticles ondiabetes-induced  14(12):2077-2091.
             retinal vascular leakage[J]. Int J Nanomed,2016. DOI:  [24]  SONG ZW,LIN Y,ZHANG X,et al. Cyclic RGD pep-
             10.2147/IJN.S108452.                               tide-modified liposomal drug delivery system for targeted
        [12]  LI F,LIAO ZC,ZHAO J,et al. Efficacy and safety of apa-  oral apatinib administration:enhanced cellular uptake and
             tinib in stage Ⅳ sarcomas:experience of a major sarcoma  improved therapeutic effects[J]. Int J Nanomed,2017.
             center in China[J]. Oncotarget,2017,8(38):64471-   DOI:10.2147/IJN.S125573.
             64480.                                        [25]  徐杉,吴敬波,傅少志.水凝胶在抗肿瘤药物中的研究进
        [13]  陈莹,平其能.口服载药纳米粒的研究进展[J].药学进展,                      展[J].中国现代应用药学,2016,33(5):676-682.


        中国药房    2020年第31卷第12期                                            China Pharmacy 2020 Vol. 31 No. 12  ·1531  ·
   128   129   130   131   132   133   134   135   136   137   138