Page 128 - 2019年2月第30卷第4期
P. 128

domized,double-blind,placebo-controlled,parallel-group,  a novel kinase inhibitor of mitogen-activated protein ki-
             dose-comparison study[J]. J Eur Acad Dermatol Venereol,  nase/extracellular signal-regulated kinase kinase-1 and mi-
             2013,27(3):e376-e383.                              togen-activated protein kinase/extracellular signal-regulat-
        [27]  AHLUWALIA J,UDKOFF J,WALDMAN A,et al. Phos-       ed kinase kinase kinase-1:in vivo effects on cutaneous in-
             phodiesterase 4 inhibitor therapies for atopic dermatitis:  flammatory responses by topical administration[J]. J Phar-
             progress and outlook[J]. Drugs,2017,77(13):1389-   macol Exp Ther,2010,335(1):123-131.
             1397.                                         [39]  KORPANTY G,SMYTH E. Anti-VEGF strategies-from
        [28]  RØNHOLT K,IVERSEN L. Old and new biological thera-  antibodies to tyrosine kinase inhibitors:background and
             pies for psoriasis[J]. Int J Mol Sci,2017. DOI:10.3390/  clinical development in human cancer[J]. Curr Pharm
             ijms18112297.                                      Des,2012,18(19):2680-2701.
        [29]  SUGIYAMA H,MCCORMICK TS,COOPER KD,et al.     [40]  JUNG K,LEE D,LIM HS,et al. Double anti-angiogenic
             Alefacept in the treatment of psoriasis[J]. Clin Dermatol,  and anti-inflammatory protein valpha targeting VEGF-A
             2008,26(4):503-508.                                and TNF-α in retinopathy and psoriasis[J]. J Biol Chem,
        [30]  HERNÁNDEZ P,MORENO E,AIRA LE,et al. Therapeu-     2011,286(16):14410-14418.
             tic targeting of CD6 in autoimmune diseases:a review of  [41]  PAPP K,BISSONNETTE R,ROSOPH L,et al. Efficacy
             cuban clinical studies with the antibodies IOR-T1 and  of ISA247 in plaque psoriasis:a randomised,multicentre,
             itolizumab[J]. Curr Drug Targets,2016,17(6):666-677.  double-blind,placebo-controlled phase Ⅲ study[J]. Lan-
        [31]  KRUPASHANKAR DS,DOGRA S,KURA M,et al. Effi-       cet,2008. DOI:10.1016/S0140-6736(08)60593-0.
             cacy and safety of itolizumab,a novel anti-CD6 monoclo-  [42]  ATWAN A,INGRAM JR,ABBOTT R,et al. Oral fumaric
             nal antibody,in patients with moderate to severe chronic  acid esters for psoriasis(review)[J]. Cochrane Database
             plaque psoriasis:results of a double-blind,randomized,  Syst Rev,2015. DOI:10.1002/14651858.CD010497.pub2.
             placebo-controlled,phase-Ⅲ study[J]. J Am Acad Derma-  [43]  FALLAH ARANI S,NEUMANN H,HOP WC,et al. Fu-
             tol,2014,71(3):484-492.                            marates vs. methotrexate in moderate to severe chronic
        [32]  PORTS WC,KHAN S,LAN S,et al. A randomized phase   plaque psoriasis:a multicentre prospective randomized
             2a efficacy and safety trial of the topical Janus kinase in-  controlled clinical trial[J]. Br J Dermatol,2011,164(4):
             hibitor tofacitinib in the treatment of chronic plaque psori-  855-861.
             asis[J]. Br J Dermatol,2013,169(1):137-145.   [44]  REICH K,ORTONNE JP,GOTTLIEB AB,et al. Success-
        [33]  ORTIZ-IBÁÑEZ K,ALSINA MM,MUÑOZ-SANTOS C.          ful treatment of moderate to severe plaque psoriasis with
             Tofacitinib and other kinase inhibitors in the treatment of  the PEGylated Fab’certolizumab pegol:results of a phase
             psoriasis[J]. Actas Dermosifiliogr,2013,104(4):304-  Ⅱ randomized,placebo-controlled trial with a re-treat-
             310.                                               ment extension[J]. Br J Dermatol,2012,167(1):180-
        [34]  PAPP KA,MENTER MA,RAMAN M,et al. A random-        190.
             ized phase 2b trial of baricitinib,an oral Janus kinase  [45]  谢明星,祁凤娥,马秋华,等.窄谱中波紫外线联合白芍总
            (JAK)1/JAK2 inhibitor,in patients with moderate-to-se-  苷胶囊和尿素乳膏治疗寻常型银屑病的临床观察[J].中
             vere psoriasis[J]. Br J Dermatol,2016,174(6):1266-  国药房,2018,29(8):1106-1108.
             1276.                                         [46]  毛荣超,唐美,邓仁远,等.紫丹银屑颗粒联合阿维A胶囊
        [35]  HE X,KOENEN HJ,SMEETS RL,et al. Targeting PKC     和复方氟米松软膏治疗寻常型银屑病的临床观察[J].中
             in human T cells using sotrastaurin(AEB071)preserves  国药房,2018,29(6):800-804.
             regulatory T cells and prevents IL-17 production[J]. J In-  [47]  中华医学会皮肤性病学分会银屑病学组.中国银屑病治
             vest Dermatol,2014,134(4):975-983.                 疗指南(2008 版)[J].中华皮肤科杂志,2009,42(3):
        [36]  MACEYKA M,SPIEGEL S. Sphingolipid metabolites in  213-214.
             inflammatory disease[J]. Nature,2014. DOI:10.1038/na-  [48]  KUMAR R,DOGRA S,AMARJI B,et al. Efficacy of
             ture13475.                                         novel topical liposomal formulation of cyclosporine in
        [37]  VACLAVKOVAA,CHIMENTI S,ARENBERGER P,et al.        mild to moderate stable plaque psoriasis:a randomized
             Oral ponesimod in patients with chronic plaque psoriasis:  clinical trial[J]. JAMA Dermatol,2016,152(7):807-815.
             a randomised,double-blind,placebo-controlled phase 2 tri-  (收稿日期:2018-05-28 修回日期:2018-12-17)
             al[J]. Lancet,2014. DOI:10.1016/S0140-6736(14)60803-5.                             (编辑:余庆华)
        [38]  MURAMOTO K,GOTO M,INOUE Y,et al. E6201,


        中国药房    2019年第30卷第4期                                               China Pharmacy 2019 Vol. 30 No. 4  ·547  ·
   123   124   125   126   127   128   129   130   131   132   133