Page 12 - 《中国药房》2026年10期

静脉制剂外配处方闭环管理模式构建与探索
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谢旭华 ，伍 云，黄松清，黄煜堃，陈思妍，曾 铮，唐微艳，何佐隆，周春霞，张宏亮（广西医科大学第一附属医
院药学部，南宁 530021）

中图分类号 R95 文献标志码 A 文章编号 1001-0408（2026）10-1246-05
DOI 10.6039/j.issn.1001-0408.2026.10.02

摘 要 目的 构建静脉制剂外配处方全流程闭环管理模式，为静脉制剂外配处方规范化管理提供参考。方法 基于我院前期牵
头制定的《静脉制剂外配处方闭环管理广西专家共识》，通过多学科团队头脑风暴法与鱼骨图框架，系统识别全流程风险点，制定
并实施限定外配合作药店与药品目录、运维医院信息系统和静脉用药调配中心（PIVAS）智能管理平台、强化全链条人员差异化培
训等策略，构建以PIVAS为核心枢纽、日间化疗中心为安全终端的全流程闭环管理体系。结果 共遴选出3家合作药店及涵盖35
个品规的首期药品目录，成功构建了涵盖医院门诊开药、患者药店购药、PIVAS配药和日间化疗中心用药四大模块的闭环管理流
程，实现了静脉制剂外配处方与院内溶媒的强制关联成组、药品追溯码的全程核验、输注参数的智能监测与全流程数据追溯。
结论 所构建的模式有效解决了静脉外配药品从院外流转至院内使用的衔接与安全管控问题，初步实现了流程的标准化、信息的
可追溯化与用药风险的主动防控。
关键词 静脉制剂外配处方；静脉用药调配中心；闭环管理；日间化疗；双通道政策

Development and exploration of a closed-loop management model for externally dispensed intravenous
prescriptions
XIE Xuhua，WU Yun，HUANG Songqing，HUANG Yukun，CHEN Siyan，ZENG Zheng，TANG Weiyan，HE
Zuolong，ZHOU Chunxia，ZHANG Hongliang（Dept. of Pharmacy， the First Affiliated Hospital of Guangxi
Medical University， Nanning 530021， China）

ABSTRACT OBJECTIVE To construct a closed-loop management model for externally dispensed intravenous prescriptions， and

to provide reference for standardized management of externally dispensed intravenous prescriptions. METHODS Based on the
Expert Consensus on Closed-loop Management of Externally Dispensed Intravenous Prescriptions in Guangxi Zhuang Autonomous
Region previously formulated by our hospital， risk points during the entire process were systematically identified through
multidisciplinary team brainstorming and a fishbone diagram. A series of strategies were subsequently formulated and implemented，
including qualifying designated external dispensing pharmacies and the drug catalogs， operating and maintaining the hospital
information system and the Pharmacy Intravenous Admixture Service （PIVAS） intelligent management platform， and strengthening
differentiated training for staff in the whole workflow. A whole-process closed-loop management system was constructed with
PIVAS as the core hub and the daytime chemotherapy center as the safety terminal. RESULTS A total of 3 cooperating pharmacies
and an initial drug list comprising 35 product specifications were selected. A closed‑loop management process encompassing hospital
outpatient prescribing， patient drug purchase in designated pharmacies， PIVAS drug dispensing， and medication use in daytime
chemotherapy center was successfully established. This system enabled the mandatory grouping and association of externally
dispensed intravenous prescriptions with in-hospital diluents， full-process verification based on drug traceability codes， intelligent
monitoring of infusion parameters， and whole-process data traceability. CONCLUSIONS The constructed model effectively
resolves the coordination and safety oversight during the use of externally dispensed intravenous drugs from out-of-hospital
circulation to in-hospital use， and has preliminarily enabled procedural standardization， whole-process information traceability， and
proactive control of medication risks.
Δ 基金项目 国家卫生健康委医院管理研究所医疗质量（循证）管
理研究项目（No.YLZLXZ23K004） KEYWORDS externally dispensed intravenous prescriptions；
＊第一作者 副主任药师，硕士。研究方向：医院药学、药事管理。 PIVAS； closed-loop management； daytime chemotherapy；
E-mail：125923075@qq.com dual-channel policy
# 通信作者 主任药师，硕士生导师，博士。研究方向：循证药学、
数据挖掘与处理。E-mail：277749097@qq.com

· 1246 · China Pharmacy 2026 Vol. 37 No. 10 中国药房 2026年第37卷第10期