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过合理的价格调整,在平衡创新药企研发回报与患者支                                 cancer: a Chinese healthcare system perspective[J]. Front
          付负担的基础上,切实保障更多乳腺癌患者能够获得有                                 Oncol,2023,13:1068463.
          效且可负担的治疗方案。本研究开展的价格敏感性情                             [13]  吴晶,刘国恩.中国药物经济学评价指南2025中英双语
          景分析,不仅能够为该药物的医保价格谈判提供量化的                                 版[M]. 北京:中国市场出版社,2025:53-55.
          数据支撑,助力其实现合理定价,同时也可为医保部门                            [14]  WAN X M,PENG L B,LI Y J. A review and comparison
          制定科学的报销政策提供依据,对进一步完善我国肿瘤                                 of methods for recreating individual patient data from pub‐
                                                                   lished Kaplan-Meier survival curves for economic evalua‐
          药物的医疗保障体系具有积极的现实意义。
                                                                   tions:a  simulation  study[J].  PLoS  One,2015,10(3):
          参考文献                                                     e0121353.
          [ 1 ]  ZENG H M,ZHENG R S,SUN K X,et al. Cancer sur‐  [15]  LIU N,ZHOU Y H,LEE J J. IPDfromKM:reconstruct in‐
               vival  statistics  in  China  2019-2021:a  multicenter,
                                                                   dividual  patient  data  from  published  Kaplan-Meier  sur‐
               population-based  study[J].  J  Natl  Cancer  Cent,2024,4  vival  curves[J].  BMC  Med  Res  Methodol,2021,21
              (3):203-213.                                        (1):111.
          [ 2 ]  GIAQUINTO  A  N,SUNG  H,NEWMAN  L  A,et  al.
                                                              [16]  何银梅,李晓,刘晓丽,等. 戈沙妥珠单抗对比单药化疗
               Breast cancer statistics 2024[J]. CA Cancer J Clin,2024,  后线治疗 HR+/HER2-晚期转移性乳腺癌的成本-效用
               74(6):477-495.                                      分析[J]. 中国药房,2024,35(20):2493-2498.
          [ 3 ]  National Comprehensive Cancer Network. NCCN clinical
                                                              [17]  JIANG W,HE Z C,ZHANG T T,et al. Cost-effectiveness
               practice  guidelines  in  oncology:cancer  breast  version  4  analysis  of  ribociclib  plus  fulvestrant  for  hormone
               [EB/OL].(2025-04-17)[2025-12-15]. https://www. nccn.  receptor-positive/human  EGF  receptor  2-negative  breast
               org/guidelines/nccn-guidelines.                     cancer[J]. Immunotherapy,2021,13(8):661-668.
          [ 4 ]  中国临床肿瘤学会指南工作委员会. 中国临床肿瘤学会
                                                              [18]  SHANG F J,ZHANG B Y,KANG S. Cost-effectiveness
              (CSCO)乳腺癌诊疗指南:2025[M]. 北京:人民卫生出版                     analysis  of  atezolizumab  plus  chemotherapy  as  first-line
               社,2025:111-119.                                     treatment  for  patients  with  advanced  nonsquamous  non-
          [ 5 ]  SPRING L M,WANDER S A,ANDRE F,et al. Cyclin-
                                                                   small-cell lung cancer in China[J]. Expert Rev Pharmaco‐
               dependent kinase 4 and 6 inhibitors for hormone receptor-  economics Outcomes Res,2023,23(3):337-343.
               positive breast cancer:past,present,and future[J]. Lancet,  [19]  梁淼,刘洋,王宪英. 埃万妥单抗联合化疗用于EGFR突
               2020,395(10226):817-827.
                                                                   变的晚期NSCLC的成本-效果分析[J]. 中国药房,2025,
          [ 6 ]  GENNARI A,ANDRÉ F,BARRIOS C H,et al. ESMO         36(6):715-720.
               clinical  practice  guideline  for  the  diagnosis,staging  and   [20]  张冉冉,张羽曦,高胜男,等. 芦康沙妥珠单抗对比单药
               treatment of patients with metastatic breast cancer[J]. Ann
                                                                   化疗用于转移性三阴性乳腺癌二线及后线治疗的成本-
               Oncol,2021,32(12):1475-1495.                        效果分析[J]. 中国药房,2025,36(16):2024-2029.
          [ 7 ]  PU  D  Q,WU Y,XU  D  B,et  al. The  adverse  events  of   [21]  WANG  K  X,LIU  S  X,WANG  R  X,et  al.  Cost-
               CDK4/6 inhibitors for HR+/HER2- breast cancer:an um‐  effectiveness  analysis  of  cadonilimab  plus  bevacizumab
               brella  review  of  meta-analyses  of  randomized  controlled
                                                                   and  chemotherapy  for  persistent,recurrent,or  metastatic
               trials[J]. Front Pharmacol,2024,15:1269922.         cervical cancer[J]. Front Immunol,2025,16:1594786.
          [ 8 ]  XU Z B,LIU Y C,SONG B H,et al. Discovery and pre‐  [22]  张森,贾才凤,王洁,等. 瑞波西利联合来曲唑一线治疗
               clinical evaluations of TQB3616,a novel CDK4-biased in‐
                                                                   HR+/HER2-晚期或转移性乳腺癌的成本-效用分析[J].
               hibitor[J]. Bioorg Med Chem Lett,2024,107:129769.   中国现代应用药学,2025,42(19):3432-3439.
          [ 9 ]  BOÉR K. Fulvestrant in advanced breast cancer:evidence   [23]  LLOYD  A,NAFEES  B,NAREWSKA  J,et  al.  Health
               to  date  and  place  in  therapy[J].  Ther  Adv  Med  Oncol,
                                                                   state utilities for metastatic breast cancer[J]. Br J Cancer,
               2017,9(7):465-479.                                  2006,95(6):683-690.
          [10]  YIN Y M,ZHANG Q Y,SUN T,et al. Novel CDK2/4/6   [24]  SONG  E,YIN  Y,ZHAO  J,et  al.  LBA25  Culmerciclib
               inhibitor culmerciclib(TQB3616) plus fulvestrant in pre‐  plus  fulvestrant  as  first-line  treatment  for  HR+/HER2-
               viously  treated,HR-positive,HER2-negative  advanced
                                                                   advanced breast cancer:a phase Ⅲ trial(CULMINATE-2)
               breast cancer:a randomized,double-blind,phase 3 trial[J].   [J]. Ann Oncol,2025,36:S1569-S1570.
               Signal Transduct Target Ther,2025,10(1):414.   [25]  ZHANG  Y  J,ZENG  X  H,DENG  H  J,et  al.  Cost-
          [11]  WU X Y,JIN N,GAO H F,et al. Effectiveness and safety
                                                                   effectiveness  analysis  of  adding  palbociclib  as  a  second-
               of palbociclib plus endocrine therapy in patients with ad‐  line endocrine therapy for HR+/HER2- metastatic breast
               vanced  breast  cancer:a  multi-center  study  in  China[J].   cancer  from  the  US  and  Chinese  perspectives[J].  Clin
               Cancers,2023,15(17):4360.
                                                                   Ther,2019,41(6):1175-1185.
          [12]  ZHU  W  T,ZHENG  M  M,XIA  P  P,et  al.  Cost-              (收稿日期:2026-01-07  修回日期:2026-04-09)
               effectiveness of palbociclib plus fulvestrant as second-line                       (编辑:孙 冰)
               therapy  of  women  with  HR+/HER2-  advanced  breast



          · 1038 ·    China Pharmacy  2026 Vol. 37  No. 8                              中国药房  2026年第37卷第8期
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