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可结合胎盘组织学、胎儿体重及存活率等指标,全面评 molecular mechanism of pachymic acid on ferroptosis in
估茯苓酸对母胎结局的影响,进一步明确其临床转化潜 renal ischemia reperfusion injury[J]. Mol Med Rep,2021,
力;同时,也可通过细胞实验深入验证茯苓酸的药理机 23(1):63.
制及潜在临床药用价值。 [11] LIU M Z,JAYARAMAN K,GIRI T,et al. Role of SIRT1
参考文献 in isoflurane conditioning-induced neurovascular protec‐
tion against delayed cerebral ischemia secondary to su-
[ 1 ] LIAO Y L,DING Y L,YU L,et al. Exploring the mecha‐
barachnoid hemorrhage[J]. Int J Mol Sci,2021,22(8):
nism of Alisma orientale for the treatment of pregnancy in‐
4291.
duced hypertension and potential hepato-nephrotoxicity
[12] NG’ETHE W,PULEI A,ONDIEKI D,et al. Outcomes of
by using network pharmacology,network toxicology,mo‐
pregnancy-related acute kidney injury:a retrospective
lecular docking and molecular dynamics simulation[J].
study in the obstetric critical care unit at Kenyatta Na‐
Front Pharmacol,2022,13:1027112.
tional Hospital 2020 to 2023[J]. PLoS Glob Public Health,
[ 2 ] ZHAO Y,WANG Y,TONG F,et al. Epidemiology of ma‐
2025,5(4):e0004396.
ternal hypertensive disorders[J]. Hypertension,2025,82
[13] DENNIS A T,XIN A N,FARBER M K. Perioperative
(5):e88-e101.
management of patients with preeclampsia:a comprehen‐
[ 3 ] NELSON-PIERCY C,SRISAWAT N,KASHANI K,et al.
sive review[J]. Anesthesiology,2025,142(2):378-402.
Pregnancy-associated acute kidney injury:consensus re‐
[14] ZHANG C,XIONG Y K,GONG M Y,et al. Pachymic
port of the 32nd Acute Disease Quality Initiative work‐
acid ameliorates fructose-driven hyperuricemic nephropa‐
group[J]. Nat Rev Nephrol,2025,21(9):633-646.
thy in mice by suppressing ferroptosis via activating Nrf2/
[ 4 ] DINES V,SUVAKOV S,KATTAH A,et al. Preeclampsia
GPX-4 pathway[J]. J Agric Food Chem,2025,73(36):
and the kidney:pathophysiology and clinical implications
22778-22793.
[J]. Compr Physiol,2023,13(1):4231-4267.
[15] LANG X,LIU W,CHEN Q F,et al. Resveratrol inhibits
[ 5 ] ZHAO Y,JIA Q,HAO G M,et al. Jiangyatongluo decoc‐
multiple organ injury in preeclampsia rat model[J]. Acta
tion ameliorates tubulointerstitial fibrosis via regulating
Biochim Pol,2023,70(1):131-135.
the SIRT1/PGC-1α/mitophagy axis in hypertensive ne‐
[16] TANG K F,XU S H,CHEN P,et al. Potential role of glu‐
phropathy[J]. Front Pharmacol,2024,15:1491315.
tathione S-transferase M1 gene polymorphism in kidney
[ 6 ] KO S F,YANG C C,SUNG P H,et al. Dapagliflozin-
calcium oxalate stone formation[J]. Int Urol Nephrol,
entresto protected kidney from renal hypertension via
2024,56(3):887-892.
downregulating cell-stress signaling and upregulating [17] ZHANG S,FENG X J,YANG G Y,et al. Dexmedetomi‐
SIRT1/PGC-1α/Mfn2-medicated mitochondrial homeosta‐ dine ameliorates acute kidney injury by regulating mito‐
sis[J]. Exp Biol Med,2023,248(23):2421-2439. chondrial dynamics via the α2-AR/SIRT1/PGC-1α path‐
[ 7 ] 高秀荣,仝兴瑞,王庆海,等 . 茯苓酸调节 IL-6/JAK2/ way activation in rats[J]. Mol Med,2024,30(1):184.
STAT3 信号通路对原发性高血压大鼠内皮细胞损伤的 [18] WANG H,CHEN S S,ZHANG Y X,et al. Liu wei di
影响[J]. 河北医学,2024,30(12):1987-1993. huang decoction alleviates renal fibrosis by inhibiting en‐
[ 8 ] CAI Z Y,SHENG Z X,YAO H. Pachymic acid amelio‐ dothelial mesenchymal transitions via upregulating Sirt1
rates sepsis-induced acute kidney injury by suppressing in‐ expression and inhibiting the Wnt/β-catenin signaling
flammation and activating the Nrf2/HO-1 pathway in rats pathway[J]. Drug Des Devel Ther,2025,19:6587-6603.
[J]. Eur Rev Med Pharmacol Sci,2017,21(8):1924-1931. [19] SUN S N,YANG S R,CHENG Y,et al. Jinlida granules
[ 9 ] ZHANG W Y,YUAN W,XU N,et al. Icariin improves alleviate podocyte apoptosis and mitochondrial dysfunc‐
acute kidney injury and proteinuria in a rat model of tion via the AMPK/PGC-1α pathway in diabetic nephropa‐
pregnancy-induced hypertension[J]. Mol Med Rep,2017, thy[J]. Int J Mol Med,2025,55(2):26.
16(5):7398-7404. (收稿日期:2025-10-16 修回日期:2026-01-06)
[10] JIANG G P,LIAO Y J,HUANG L L,et al. Effects and (编辑:邹丽娟)
中国药房 2026年第37卷第2期 China Pharmacy 2026 Vol. 37 No. 2 · 191 ·

