Page 61 - 《中国药房》2026年2期
P. 61

可结合胎盘组织学、胎儿体重及存活率等指标,全面评                                molecular mechanism of pachymic acid on ferroptosis in
          估茯苓酸对母胎结局的影响,进一步明确其临床转化潜                                renal ischemia reperfusion injury[J]. Mol Med Rep,2021,
          力;同时,也可通过细胞实验深入验证茯苓酸的药理机                                23(1):63.
          制及潜在临床药用价值。                                        [11]  LIU M Z,JAYARAMAN K,GIRI T,et al. Role of SIRT1
          参考文献                                                    in  isoflurane  conditioning-induced  neurovascular  protec‐
                                                                  tion  against  delayed  cerebral  ischemia  secondary  to  su-
          [ 1 ]  LIAO Y L,DING Y L,YU L,et al. Exploring the mecha‐
                                                                  barachnoid  hemorrhage[J].  Int  J  Mol  Sci,2021,22(8):
              nism of Alisma orientale for the treatment of pregnancy in‐
                                                                  4291.
              duced  hypertension  and  potential  hepato-nephrotoxicity
                                                             [12]  NG’ETHE W,PULEI A,ONDIEKI D,et al. Outcomes of
              by using network pharmacology,network toxicology,mo‐
                                                                  pregnancy-related  acute  kidney  injury:a  retrospective
              lecular  docking  and  molecular  dynamics  simulation[J].
                                                                  study  in  the  obstetric  critical  care  unit  at  Kenyatta  Na‐
              Front Pharmacol,2022,13:1027112.
                                                                  tional Hospital 2020 to 2023[J]. PLoS Glob Public Health,
          [ 2 ]  ZHAO Y,WANG Y,TONG F,et al. Epidemiology of ma‐
                                                                  2025,5(4):e0004396.
              ternal  hypertensive  disorders[J].  Hypertension,2025,82
                                                             [13]  DENNIS  A  T,XIN  A  N,FARBER  M  K.  Perioperative
              (5):e88-e101.
                                                                  management of patients with preeclampsia:a comprehen‐
          [ 3 ]  NELSON-PIERCY C,SRISAWAT N,KASHANI K,et al.
                                                                  sive review[J]. Anesthesiology,2025,142(2):378-402.
              Pregnancy-associated  acute  kidney  injury:consensus  re‐
                                                             [14]  ZHANG  C,XIONG Y  K,GONG  M Y,et  al.  Pachymic
              port  of  the  32nd Acute  Disease  Quality  Initiative  work‐
                                                                  acid ameliorates fructose-driven hyperuricemic nephropa‐
              group[J]. Nat Rev Nephrol,2025,21(9):633-646.
                                                                  thy in mice by suppressing ferroptosis via activating Nrf2/
          [ 4 ]  DINES V,SUVAKOV S,KATTAH A,et al. Preeclampsia
                                                                  GPX-4  pathway[J].  J Agric  Food  Chem,2025,73(36):
              and the kidney:pathophysiology and clinical implications
                                                                  22778-22793.
              [J]. Compr Physiol,2023,13(1):4231-4267.
                                                             [15]  LANG X,LIU W,CHEN Q F,et al. Resveratrol inhibits
          [ 5 ]  ZHAO Y,JIA Q,HAO G M,et al. Jiangyatongluo decoc‐
                                                                  multiple  organ  injury  in  preeclampsia  rat  model[J]. Acta
              tion  ameliorates  tubulointerstitial  fibrosis  via  regulating
                                                                  Biochim Pol,2023,70(1):131-135.
              the  SIRT1/PGC-1α/mitophagy  axis  in  hypertensive  ne‐
                                                             [16]  TANG K F,XU S H,CHEN P,et al. Potential role of glu‐
              phropathy[J]. Front Pharmacol,2024,15:1491315.
                                                                  tathione  S-transferase  M1  gene  polymorphism  in  kidney
          [ 6 ]  KO  S  F,YANG  C  C,SUNG  P  H,et  al.  Dapagliflozin-
                                                                  calcium  oxalate  stone  formation[J].  Int  Urol  Nephrol,
              entresto  protected  kidney  from  renal  hypertension  via
                                                                  2024,56(3):887-892.
              downregulating  cell-stress  signaling  and  upregulating   [17]  ZHANG S,FENG X J,YANG G Y,et al. Dexmedetomi‐
              SIRT1/PGC-1α/Mfn2-medicated mitochondrial homeosta‐  dine  ameliorates  acute  kidney  injury  by  regulating  mito‐
              sis[J]. Exp Biol Med,2023,248(23):2421-2439.        chondrial  dynamics  via  the  α2-AR/SIRT1/PGC-1α  path‐
          [ 7 ]  高秀荣,仝兴瑞,王庆海,等 . 茯苓酸调节 IL-6/JAK2/                 way activation in rats[J]. Mol Med,2024,30(1):184.
              STAT3 信号通路对原发性高血压大鼠内皮细胞损伤的                     [18]  WANG  H,CHEN  S  S,ZHANG Y  X,et  al.  Liu  wei  di
              影响[J]. 河北医学,2024,30(12):1987-1993.                  huang decoction alleviates renal fibrosis by inhibiting en‐
          [ 8 ]  CAI Z Y,SHENG Z X,YAO H. Pachymic acid amelio‐   dothelial  mesenchymal  transitions  via  upregulating  Sirt1
              rates sepsis-induced acute kidney injury by suppressing in‐  expression and inhibiting the Wnt/β-catenin signaling
              flammation and activating the Nrf2/HO-1 pathway in rats  pathway[J]. Drug Des Devel Ther,2025,19:6587-6603.
              [J]. Eur Rev Med Pharmacol Sci,2017,21(8):1924-1931.  [19]  SUN S N,YANG S R,CHENG Y,et al. Jinlida granules
          [ 9 ]  ZHANG W Y,YUAN W,XU N,et al. Icariin improves    alleviate  podocyte  apoptosis  and  mitochondrial  dysfunc‐
              acute  kidney  injury  and  proteinuria  in  a  rat  model  of   tion via the AMPK/PGC-1α pathway in diabetic nephropa‐
              pregnancy-induced hypertension[J]. Mol Med Rep,2017,  thy[J]. Int J Mol Med,2025,55(2):26.
              16(5):7398-7404.                                              (收稿日期:2025-10-16  修回日期:2026-01-06)
          [10]  JIANG G P,LIAO Y J,HUANG L L,et al. Effects and                                   (编辑:邹丽娟)











          中国药房  2026年第37卷第2期                                                 China Pharmacy  2026 Vol. 37  No. 2    · 191 ·
   56   57   58   59   60   61   62   63   64   65   66