Page 136 - 《中国药房》2025年17期
P. 136
safety of oral semaglutide vs sitagliptin in a predomi‐ kidney disease in the FLOW trial[J]. Nat Med,2024,30
nantly Chinese population with type 2 diabetes uncon‐ (10):2849-2856.
trolled with metformin:PIONEER 12,a double-blind, [43] APPERLOO E M,GORRIZ J L,SOLER M J,et al. Sema‐
phase Ⅲ a,randomised trial[J]. Diabetologia,2024,67 glutide in patients with overweight or obesity and chronic
(9):1800-1816. kidney disease without diabetes:a randomized double-
[32] ARODA V R,ABERLE J,BARDTRUM L,et al. Efficacy blind placebo-controlled clinical trial[J]. Nat Med,2025,
and safety of once-daily oral semaglutide 25 mg and 50 31(1):278-285.
mg compared with 14 mg in adults with type 2 diabetes [44] GARCÍA DE LUCAS M D, CABALLERO I,
(PIONEER PLUS):a multicentre,randomised,phase 3b FERNÁNDEZ-GARCÍA J C,et al. Influence of chronic
trial[J]. Lancet,2023,402(10403):693-704. kidney disease and its severity on the efficacy of semaglu‐
[33] PRATLEY R E,ARODA V R,LINGVAY I,et al. Sema‐ tide in type 2 diabetes patients:a multicenter real-world
glutide versus dulaglutide once weekly in patients with study[J]. Front Endocrinol (Lausanne) ,2023,14:
type 2 diabetes (SUSTAIN 7):a randomised,open-label, 1240279.
phase 3b trial[J]. Lancet Diabetes Endocrinol,2018,6(4): [45] COLHOUN H M,LINGVAY I,BROWN P M,et al. Long-
275-286. term kidney outcomes of semaglutide in obesity and car‐
[34] ARODA V R,ERHAN U,JELNES P,et al. Safety and diovascular disease in the SELECT trial[J]. Nat Med,
tolerability of semaglutide across the SUSTAIN and 2024,30(7):2058-2066.
PIONEER phase Ⅲa clinical trial programmes[J]. Diabe‐ [46] ANDERER S. FDA approves semaglutide to reduce risk
tes Obes Metab,2023,25(5):1385-1397. of kidney disease progression[J]. JAMA,2025,333(13):
[35] GARG S K,KAUR G,HAIDER Z,et al. Efficacy of 1109.
semaglutide in overweight and obese patients with type 1 [47] ESCOBAR-MORREALE H F. Polycystic ovary syn‐
diabetes[J]. Diabetes Technol Ther,2024,26(3):184-189. drome:definition,aetiology,diagnosis and treatment[J].
[36] LINGVAY I,DEANFIELD J,KAHN S E,et al. Semaglu‐ Nat Rev Endocrinol,2018,14(5):270-284.
tide and cardiovascular outcomes by baseline HbA1c and [48] JENSTERLE M,FERJAN S,LEŽAIČ L K,et al. Sema‐
change in HbA1c in people with overweight or obesity but glutide delays 4-hour gastric emptying in women with
without diabetes in SELECT[J]. Diabetes Care,2024,47 polycystic ovary syndrome and obesity[J]. Diabetes Obes
(8):1360-1369. Metab,2023,25(4):975-984.
[37] KAHN S E,DEANFIELD J E,JEPPESEN O K,et al. Ef‐ [49] ZHU K,KAKKAR R,CHAHAL D,et al. Efficacy and
fect of semaglutide on regression and progression of gly‐ safety of semaglutide in non-alcoholic fatty liver disease
cemia in people with overweight or obesity but without [J]. World J Gastroenterol,2023,29(37):5327-5338.
diabetes in the SELECT trial[J]. Diabetes Care,2024,47 [50] 牟钰钦,罗易,王思琪,等. 司美格鲁肽药物不良反应的
(8):1350-1359. 临床表现及相关影响因素分析[J]. 保健医学研究与实
[38] IRFAN H. Obesity,cardiovascular disease,and the pro- 践,2024,21(6):105-109.
mising role of semaglutide:insights from the SELECT [51] 孙如男,仓代晓,全香花,等. 司美格鲁肽致药品不良反
trial[J]. Curr Probl Cardiol,2024,49(1 Pt A):102060. 应文献分析[J]. 中国药房,2024,35(18):2266-2271.
[39] SOLOMON S D,OSTROMINSKI J W,WANG X W, [52] BROWN C. High price and demand for semaglutide
et al. Effect of semaglutide on cardiac structure and func‐ means lack of access for US patients[J]. BMJ,2023,382:
tion in patients with obesity-related heart failure[J]. J Am 1863.
Coll Cardiol,2024,84(17):1587-1602. [53] BUSE J B,WEXLER D J,TSAPAS A,et al. 2019 update
[40] HUSAIN M,CONSOLI A,DE REMIGIS A,et al. Sema‐ to:management of hyperglycemia in type 2 diabetes,
glutide reduces cardiovascular events regardless of metfor‐ 2018. A consensus report by the American Diabetes Asso‐
min use:a post hoc subgroup analysis of SUSTAIN 6 and ciation (ADA) and the European Association for the
PIONEER 6[J]. Cardiovasc Diabetol,2022,21(1):64. Study of Diabetes (EASD) [J]. Diabetes Care,2020,43
[41] JIANG Z M,WANG Y,ZHAO X,et al. Obesity and (2):487-493.
chronic kidney disease[J]. Am J Physiol Endocrinol [54] FEZZA R,RAINS B,FEZZA T,et al. Emerging anesthe‐
Metab,2023,324(1):E24-E41. sia risks with semaglutide[J]. Plast Reconstr Surg Glob
[42] MANN J F E,ROSSING P,BAKRIS G,et al. Effects of Open,2023,11(11):e5427.
semaglutide with and without concomitant SGLT2 inhibi‐ (收稿日期:2025-04-18 修回日期:2025-08-05)
tor use in participants with type 2 diabetes and chronic (编辑:唐晓莲)
· 2210 · China Pharmacy 2025 Vol. 36 No. 17 中国药房 2025年第36卷第17期

