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综 上 所 述 ,棕 矢 车 菊 素 可 能 通 过 调 控 AMPK/ DENG H Z,CHEN K,LI P,et al. Ginsenoside Rg1 inhi-
NLRP3 信号通路来抑制 OA 大鼠炎症反应及细胞外基 bits pulmonary fibrosis in rats by regulating AMPK/
质降解。 NLRP3 pathway-mediated pyroptosis[J]. Chin Tradit Herb
参考文献 Drugs,2023,54(3):841-848.
[ 1 ] MORAIS S V,MENDONÇA P G,VASCONCELOS C C, [11] 徐田杰,樊佳欣,郭小玲,等 . 二甲双胍抑制 PI3K/AKT/
mTOR信号通路保护骨关节炎模型大鼠关节软骨[J].中
et al. Cuminaldehyde effects in a MIA-induced experimen‐
国组织工程研究,2025,29(5):1003-1012.
tal model osteoarthritis in rat knees[J]. Metabolites,2023,
XU T J,FAN J X,GUO X L,et al. Metformin exerts a
13(3):397.
[ 2 ] GAN D H,TAO C,JIN X W,et al. Piezo1 activation protective effect on articular cartilage in osteoarthritis rats
by inhibiting the PI3K/AKT/mTOR pathway[J]. CJTER,
accelerates osteoarthritis progression and the targeted
therapy effect of artemisinin[J]. J Adv Res,2024,62: 2025,29(5):1003-1012.
105-117. [12] KAWATA M,MCCLATCHY D B,DIEDRICH J K,et al.
Mocetinostat activates Krüppel-like factor 4 and protects
[ 3 ] ZHANG Z W,WANG S,LIU X Q,et al. Secoisolarici‐
resinol diglucoside ameliorates osteoarthritis via nuclear against tissue destruction and inflammation in osteoarthri‐
tis[J]. JCI Insight,2023,8(17):e170513.
factor-erythroid 2-related factor-2/nuclear factor kappa B [13] ZHAO X Y,DUAN B Q,WU J N,et al. Bilirubin amelio‐
pathway:in vitro and in vivo experiments[J]. Biomed Phar‐
rates osteoarthritis via activating Nrf2/HO-1 pathway and
macother,2023,164:114964. suppressing NF-κB signalling[J]. J Cell Mol Med,2024,
[ 4 ] CUI X,WANG M F,LI H,et al. Tenacissoside G alle-
28(7):e18173.
viated osteoarthritis through the NF-κB pathway both in [14] KNIGHTS A J,REDDING S J,MAERZ T. Inflammation
vitro and in vivo[J]. Immunol Lett,2023,258:24-34. in osteoarthritis:the latest progress and ongoing challenges
[ 5 ] NAGEEN B,RASUL A,HUSSAIN G,et al. Jaceosidin:a
[J]. Curr Opin Rheumatol,2023,35(2):128-134.
natural flavone with versatile pharmacological and bio‐
[15] WANG X Y,PENG Z P,WANG L,et al. Cordyceps mili‐
logical activities[J]. Curr Pharm Des,2021,27(4):
taris solid medium extract alleviates lipoteichoic acid-
456-466. induced MH-S inflammation by inhibiting TLR2/NF-κB/
[ 6 ] LEE H,JANG D,JEON J,et al. Seomae mugwort and
NLRP3 pathways[J]. Int J Mol Sci,2023,24(21):15519.
jaceosidin attenuate osteoarthritic cartilage damage by [16] LIU Y Z,ZHOU L Y,DU B B,et al. Protection against
blocking IκB degradation in mice[J]. J Cell Mol Med, doxorubicin-related cardiotoxicity by jaceosidin involves
2020,24(14):8126-8137.
the Sirt1 signaling pathway[J]. Oxid Med Cell Longev,
[ 7 ] JIANG X L,LU Z J,ZHANG Q,et al. Osthole:a poten‐ 2021,2021:9984330.
tial AMPK agonist that inhibits NLRP3 inflammasome
[17] HUANG X L,WEI X C,GUO L Q,et al. The therapeutic
activation by regulating mitochondrial homeostasis for effects of Jaceosidin on lipopolysaccharide-induced acute
combating rheumatoid arthritis[J]. Phytomedicine,2023,
lung injury in mice[J]. J Pharmacol Sci,2019,140(3):
110:154640. 228-235.
[ 8 ] 蔡猛,陈文恒,徐琳琳,等 . 基于 AMPK/ULK1 介导的自 [18] ZHUANG H M,REN X S,JIANG F Z,et al. Indole-3-
噬通路探究牛蒡子苷元对骨关节炎大鼠软骨细胞焦亡 propionic acid alleviates chondrocytes inflammation and
的影响[J]. 中国药学杂志,2023,58(20):1839-1848. osteoarthritis via the AhR/NF-κB axis[J]. Mol Med,2023,
CAI M,CHEN W H,XU L L,et al. Effect of arctigenin 29(1):17.
on chondrocyte pyroptosis in osteoarthritis rats based on [19] WANG Z Y,SHI W M,WU L H,et al. TMF inhibits
AMPK/ULK1-mediated autophagy pathway[J]. Chin extracellular matrix degradation by regulating the C/EBPβ/
Pharm J,2023,58(20):1839-1848. ADAMTS5 signaling pathway in osteoarthritis[J]. Biomed
[ 9 ] 汤洁,李烨,胡勇,等 . 瑞香素调节 MCP-1/CCR2 通路对 Pharmacother,2024,174:116501.
骨关节炎大鼠软骨细胞焦亡的影响[J]. 中国骨质疏松杂 [20] ZHANG J,HUANG L L,SHI X,et al. Metformin protects
志,2024,30(12):1731-1736. against myocardial ischemia-reperfusion injury and cell
TANG J,LI Y,HU Y,et al. Effect of daphnetin on pyrop‐ pyroptosis via AMPK/NLRP3 inflammasome pathway[J].
tosis of chondrocytes in osteoarthritis rats by regulating Aging(Albany NY),2020,12(23):24270-24287.
the MCP-1/CCR2 pathway[J]. Chin J Osteoporos,2024, [21] GUO R,GAO S T,FENG Y,et al. Ulinastatin attenuates
30(12):1731-1736. spinal cord injury by targeting AMPK/NLRP3 signaling
[10] 邓宏哲,陈昆,李鹏,等 . 人参皂苷 Rg1通过调控 AMPK/ pathway[J]. J Chem Neuroanat,2022,125:102145.
NLRP3通路介导的细胞焦亡抑制大鼠肺纤维化研究[J]. (收稿日期:2024-08-12 修回日期:2025-01-09)
中草药,2023,54(3):841-848. (编辑:邹丽娟)
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