Page 111 - 《中国药房》2025年4期
P. 111

究对信迪利单抗用于胆管癌的安全性数据进行了补充,                           [12]  JIN S L,ZHAO R H,ZHOU C,et al. Feasibility and tole-
          可为其适应证增加胆管癌领域提供医学依据。由于本                                 rability  of  sintilimab  plus  anlotinib  as  the  second-line
          研究纳入的样本量较小、观察时间较短,所得结论尚需                                therapy for patients with advanced biliary tract cancers:an
          更多大规模、多中心的前瞻性研究进一步证实。                                   open-label,single-arm,phase Ⅱ clinical trial[J]. Int J Can‐
          参考文献                                                    cer,2023,152(8):1648-1658.
          [ 1 ]  朱丹,李月阳,宋燕青,等. PD-1抑制剂信迪利单抗的临                [13]  王忠辉,陈国林,苏树英. 安罗替尼联合信迪利单抗治疗
                                                                  复发性胆管癌1例[J]. 岭南现代临床外科,2022,22(6):
              床研究进展[J]. 中国医院药学杂志,2020,40(1):120-123.
              ZHU D,LI Y Y,SONG Y Q,et al. The clinical research   582-587.
                                                                  WANG Z H,CHEN G L,SU S Y. Effective treatment of
              progress  of  PD-1  inhibitor:sintilimab[J].  Chin  J  Hosp
              Pharm,2020,40(1):120-123.                           recurrent  cholangiocarcinoma  with  arotinib  combined
          [ 2 ]  夏铮铮,张见雨,曲爽,等. 某肿瘤医院信迪利单抗超适                       with  sintilimab  injection:a  case  report  and  literature
              应证用药循证评价[J]. 今日药学,2023,33(5):352-355.               review[J]. Lingnan Mod Clin Surg,2022,22(6):582-587.
              XIA  Z  Z,ZHANG  J  Y,QU  S,et  al.  Evidence-based       [14]  LIU J,WANG C Y,CAO L,et al. Treatment of advanced
              evaluation of off-label use of sintilimab in a cancer hospital  intrahepatic  cholangiocarcinoma  with  sintilimab  com‐
              [J]. Pharm Today,2023,33(5):352-355.                bined  with  tegafur-gimeracil-oteracil  potassium  capsules
                                                                 (S-1):a  case  report[J]. Ann  Palliat  Med,2020,9(2):
          [ 3 ]  KHAN S A,TAVOLARI S,BRANDI G. Cholangiocarci‐
                                                                  497-503.
              noma:epidemiology and risk factors[J]. Liver Int,2019,
              39(Suppl. 1):19-31.                            [15]  ZHANG J J,WU L H,LIU J,et al. A metastatic intrahe‐
          [ 4 ]  BANALES  J  M,MARIN  J  J  G,LAMARCA  A,et  al.   patic  cholangiocarcinoma  treated  with  programmed  cell
              Cholangiocarcinoma  2020:the  next  horizon  in  mecha‐  death  1  inhibitor:a  case  report  and  literature  review[J].
              nisms and management[J]. Nat Rev Gastroenterol Hepatol,  Immunotherapy,2020,12(8):555-561.
              2020,17(9):557-588.                            [16]  中国临床肿瘤学会指南工作委员会. 中国临床肿瘤学会
          [ 5 ]  VALLE J W,FURUSE J,JITLAL M,et al. Cisplatin and   (CSCO)胆道恶性肿瘤诊疗指南2021[M]. 北京:人民卫
              gemcitabine  for  advanced  biliary  tract  cancer:a  meta-  生出版社,2021:119-137.
                                                                  Chinese Society of Clinical Oncology Guidelines Working
              analysis of two randomised trials[J]. Ann Oncol,2014,25
                                                                  Committee.  Chinese  Society  of  Clinical  Oncology
              (2):391-398.
          [ 6 ]  RIMINI  M,FORNARO  L,LONARDI  S,et  al. Durva-  (CSCO)diagnosis  and  treatment  guidelines  for  biliary
              lumab plus gemcitabine and cisplatin in advanced biliary   malignancy 2021 [M]. Beijing:People’s Medical Publishing
              tract  cancer:an  early  exploratory  analysis  of  real-world   House,2021:119-137.
              data [J] . Liver Int,2023,43(8):1803-1812.     [17]  陈静静,钱佩佩,曹凯,等. 我国药品不良反应关联性评
          [ 7 ]  OH  D Y,LEE  K  H,LEE  D  W,et  al.  Gemcitabine  and     价方法与诺氏评估量表法的对比与分析[J]. 中国药事,
              cisplatin plus durvalumab with or without tremelimumab   2020,34(8):988-992.
              in chemotherapy-naive patients with advanced biliary tract   CHEN  J  J,QIAN  P  P,CAO  K,et  al.  Comparison  and
              cancer:an  open-label,single-centre,phase  2  study[J].    analysis  of  causality  assessment  method  in  China  and
              Lancet Gastroenterol Hepatol,2022,7(6):522-532.     Naranjo’s method in the evaluation of adverse drug reac‐
          [ 8 ]  OH D Y,HE A R,QIN S K,et al. Durvalumab plus gem‐  tions[J]. Chin Pharm Aff,2020,34(8):988-992.
              citabine  and  cisplatin  in  advanced  biliary  tract  cancer[J].   [18]  National  Cancer  Institute.  Common  terminology  criteria
              NEJM Evid,2022,1(8):EVIDoa2200015.                  for adverse events (CTCAE) version 5.0.[EB/OL]. [2023-
          [ 9 ]  SHI G M,HUANG X Y,WU D,et al. Toripalimab com‐   11-27]. https://ctep.cancer.gov/protocoldevelopment/
              bined  with  lenvatinib  and  GEMOX  is  a  promising  regi‐  electronic_applications/docs/CTCAE_v5_Quick_Reference_
              men as first-line treatment for advanced intrahepatic cho-  8.5x11.pdf.
              langiocarcinoma:a single-center,single-arm,phase 2   [19]  YOST K E,SATPATHY A T,WELLS D K,et al. Clonal
                                                                  replacement  of  tumor-specific  T  cells  following  PD-1
              study[J]. Signal Transduct Target Ther,2023,8(1):106.
          [10]  KELLEY R K,UENO M,YOO C,et al. Pembrolizumab      blockade[J]. Nat Med,2019,25(8):1251-1259.
              in  combination  with  gemcitabine  and  cisplatin  compared   [20]  杜成,金山琇,谢晓冬. 从微观到宏观漫谈肿瘤免疫检查
              with  gemcitabine  and  cisplatin  alone  for  patients  with      点抑制剂疗效的影响因素[J]. 中国癌症防治杂志,2021,
              advanced  biliary  tract  cancer(KEYNOTE-966):a  ran‐  13(6):575-584.
              domised,double-blind,placebo-controlled,phase  3  trial  DU C,JIN S X,XIE X D. A discussion of the influencing
              [J]. Lancet,2023,401(10391):1853-1865.              factors of the efficacy of tumor immune checkpoint inhibi‐
          [11]  DING X Y,LI G X,SUN W,et al. Sintilimab combined   tors:from  the  micro  to  the  macro[J].  Chin  J  Oncol  Prev
              with  lenvatinib  for  advanced  intrahepatic  cholangiocarci‐  Treat,2021,13(6):575-584.
                                                                            (收稿日期:2024-08-14  修回日期:2025-01-23)
              noma  in  second-line  setting:a  multi-center  observational
                                                                                                  (编辑:陈 宏)
              study[J]. Front Oncol,2022,12:907055.


          中国药房  2025年第36卷第4期                                                 China Pharmacy  2025 Vol. 36  No. 4    · 485 ·
   106   107   108   109   110   111   112   113   114   115   116