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推荐剂量为 15 mg,qd。本案例的体重为 44 kg,肝肾功                         crophorum(Necrobacillosis),with a focus on Lemierre’s
          能均正常,故予利伐沙班片 15 mg,qd,出院后继续口服                            syndrome[J]. Clin Microbiol Rev,2007,20(4):622-659.
          至足疗程(4 周)。临床药师对患者进行用药教育,嘱使                          [10]  VIJAY V,FATTAH Z. Lesson of the month 1:Lemierre’s
          用抗菌药物期间禁止饮用含有酒精的饮料,密切观察有                                 syndrome:a reminder of the “forgotten disease”[J]. Clin
                                                                   Med,2018,18(1):100-102.
          无黑便、皮下瘀斑、牙龈出血等情况。2 个月后,复查结
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          果示患者恢复良好,超声检测示双侧颈部大血管旁无明
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          显异常,无出血等其他不适。
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          4 结语                                                [12]  CHAKER K,BERRADA O,LYOUBI M,et al. Lemierre’s
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          人员应提高对LS诊断及治疗的认识。在本案例的治疗                                 ture review[J]. Int J Surg Case Rep,2021,78:151-154.
          过程中,临床先进行了细菌培养,但未得到明确的病原                            [13]  ITO  I,KADOWAKI  S,TANABE  N,et  al.  Tazobactam/
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          尚无相关指南共识指导,治疗数据十分有限,临床药师
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          通过解读血 mNGS 检测结果,查阅大量循证医学证据,
                                                                   drome in the pediatric population:trends in disease presen‐
          运用药学专业特长,协助医师制定了 LS 患者的抗感染
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          和抗凝治疗方案,为其个体化用药提供了依据,保障了                                 rhinolaryngol,2020,136:110213.
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          · 1000 ·    China Pharmacy  2024 Vol. 35  No. 8                              中国药房  2024年第35卷第8期
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