Page 87 - 《中国药房》2024年5期
P. 87

Kidney Int,2021,100(4S):S1-S276.                    BMC Pharmacol Toxicol,2018,19(1):14.
          [ 2 ]  李馥伶,林美钦,宋洪涛,等. 影响他克莫司体内药动学                  [11]  LIAO M H,WANG M L,ZHU X,et al. Tacrolimus popu‐
              参数、临床疗效的因素[J]. 中国药房,2016,27(2):                     lation  pharmacokinetic  model  in  adult  Chinese  patients
              279-282.                                            with  nephrotic  syndrome  and  dosing  regimen  identifica‐
              LI  F  L,LIN  M  Q,SONG  H  T,et  al.  Factors  affecting   tion using Monte Carlo simulations[J]. Ther Drug Monit,
              pharmacokinetic parameters and clinical efficacy of tacro‐  2022,44(5):615-624.
              limus in vivo[J]. China Pharm,2016,27(2):279-282.  [12]  THÖLKING  G,SCHÜTTE-NÜTGEN  K,SCHMITZ  J,
          [ 3 ]  ZHENG P,YU Z,LI L R,et al. Predicting blood concen‐  et al. A low tacrolimus concentration/dose ratio increases
              tration of tacrolimus in patients with autoimmune diseases   the risk for the development of acute calcineurin inhibitor-
              using  machine  learning  techniques  based  on  real-world   induced nephrotoxicity[J]. J Clin Med,2019,8(10):1586.
              evidence[J]. Front Pharmacol,2021,12:727245.   [13]  SONG  J  L,LI  M,YAN  L  N,et  al.  Higher  tacrolimus
          [ 4 ]  CHEN H X,CHENG Q,LI F,et al. Efficacy and safety of   blood  concentration  is  related  to  increased  risk  of  post-
              tacrolimus  and  low-dose  prednisone  in  Chinese  children   transplantation  diabetes  mellitus  after  living  donor  liver
              with steroid-resistant nephrotic syndrome[J]. World J Pediatr,  transplantation[J]. Int J Surg,2018,51:17-23.
              2020,16(2):159-167.                            [14]  凌静,蒋艳,邹素兰,等. 肾病综合征患者他克莫司的群
          [ 5 ]  POPESCU M C,BALAS V E,PERESCU-POPESCU L,         体药动学研究[J]. 中国现代应用药学,2020,37(24):
              et  al.  Multilayer  perceptron  and  neural  networks[J].   3019-3024.
              WSEAS Trans Circuits Syst,2009,8(7):579-588.        LING J,JIANG Y,ZOU S L,et al. Population pharmaco‐
          [ 6 ]  LIANG  T,SHEN  J  H,ZHANG  S  M,et  al.  Using   kinetics of tacrolimus in patients with nephrotic syndrome
              ultrasound-based  multilayer  perceptron  to  differentiate   [J]. China Ind Econ,2020,37(24):3019-3024.
              early breast mucinous cancer and its subtypes from fibro‐  [15]  HUANG Q B,LIN X B,WANG Y,et al. Tacrolimus phar‐
              adenoma[J]. Front Oncol,2021,11:724656.             macokinetics in pediatric nephrotic syndrome:a combina‐
          [ 7 ]  AKTER S,DAS D,HAQUE R U,et al. AD-CovNet:an      tion  of  population  pharmacokinetic  modelling  and  ma‐
              exploratory analysis using a hybrid deep learning model to   chine learning approaches to improve individual prediction
              handle data imbalance,predict fatality,and risk factors in   [J]. Front Pharmacol,2022,13:942129.
              Alzheimer’s  patients  with  COVID-19[J].  Comput  Biol   [16]  MO X L,CHEN X J,ZENG H S,et al. Tacrolimus in the
              Med,2022,146:105657.                                treatment  of  childhood  nephrotic  syndrome:machine
          [ 8 ]  WADA T,ISHIMOTO T,NAKAYA  I,et  al. A  digest  of   learning detects novel biomarkers and predicts efficacy[J].
              the  evidence-based  clinical  practice  guideline  for  ne‐  Pharmacotherapy,2023,43(1):43-52.
              phrotic  syndrome  2020[J].  Clin  Exp  Nephrol,2021,25  [17]  YUAN W J,SUI L,XIN H L,et al. Discussion on ma‐
              (12):1277-1285.                                     chine learning technology to predict tacrolimus blood con‐
          [ 9 ]  中国成人肾病综合征免疫抑制治疗专家组. 中国成人肾                        centration in patients with nephrotic syndrome and mem‐
              病综合征免疫抑制治疗专家共识[J]. 中华肾脏病杂志,                         branous nephropathy in real-world settings[J]. BMC Med
              2014,30(6):467-474.                                 Inform Decis Mak,2022,22(1):336.
              Expert  Group  on  Immunosuppressive  Therapy  for Adult   [18]  BRUNET M,VAN GELDER T,ÅSBERG A,et al. Thera‐
              Nephrotic Syndrome in China. Expert consensus on immu‐  peutic  drug  monitoring  of  tacrolimus-personalized
              nosuppressive  therapy  for  adult  nephrotic  syndrome  in   therapy:second  consensus  report[J].  Ther  Drug  Monit,
              China[J]. Chin J Nephrol,2014,30(6):467-474.        2019,41(3):261-307.
          [10]  LI M,XU M,LIU W,et al. Effect of CYP3A4,CYP3A5              (收稿日期:2023-08-03  修回日期:2024-02-17)
              and ABCB1 gene polymorphisms on the clinical efficacy                               (编辑:胡晓霖)
              of  tacrolimus  in  the  treatment  of  nephrotic  syndrome[J].












          中国药房  2024年第35卷第5期                                                 China Pharmacy  2024 Vol. 35  No. 5    · 589 ·
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