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口服单剂量配方制药品自动核对模式的建立与优化



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          邱婷婷 ,闫盈盈,张毓宸,张晨辰,程吟楚,孔宪伟,杨毅恒(北京大学第三医院药剂科,北京 100191)
          中图分类号  R952      文献标志码  A      文章编号  1001-0408(2023)16-2018-04
          DOI  10.6039/j.issn.1001-0408.2023.16.19

          摘   要  目的  为医疗机构建立口服单剂量配方制药品自动核对模式、提高核对效率提供参考。方法  我院成立自动核对流程再
          造小组,采用ECRSI法,根据取消、合并、调整、简化、增加五大原则梳理我院单剂量配方药袋的核对流程及模式,并对硬件串联不
          佳问题和系统假阳性报错占比过高问题进行优化。随机抽取10个病区的单剂量配方药袋,比较人工核对与优化前后自动核对模
          式下的工作效率和出门差错率,以及优化前后自动核对模式下的假阳性报错情况。结果  建立口服药品单剂量配方药袋自动核对
          模式后,除心血管内科和肾脏内科外的其余8个病区的药袋平均核对用时均显著短于人工核对模式(P<0.05)。自动核对模式进
          一步优化后,所有病区的药袋平均核对用时均显著短于人工核对模式(P<0.05);与优化前的自动核对模式比较,每袋的平均核对
          用时缩短了0.43 s,有半数病区的药袋平均核对用时均显著缩短(P<0.05);同时,假阳性报错占比从优化前的96.83%下降到优化
          后92.76%(P<0.05),出门差错率从人工核对模式下的0.039‰下降到优化前的0.019‰、优化后的0.015‰(P<0.05)。结论  基于
          ECRSI法构建的口服单剂量配方制药品自动核对模式可有效降低药袋的平均核对用时,减少出门差错,提高药师的工作效率。
          关键词  单剂量配方制;ECRSI法;自动核对模式;人工核对模式;口服药品

          Construction and optimization of automatic checking mode for unit dose dispensing system of oral drugs

          QIU Tingting,YAN Yingying,ZHANG Yuchen,ZHANG Chenchen,CHENG Yinchu,KONG Xianwei,
          YANG Yiheng(Dept. of Pharmacy, Peking University Third Hospital, Beijing 100191, China)

          ABSTRACT    OBJECTIVE  To  provide  a  reference  for  establishing  an  automatic  checking  mode  and  improving  the  checking
          efficiency  of  the  unit  dose  dispensing  system  of  oral  drugs  in  hospital.  METHODS  The  automatic  checking  process  reengineering
          team was established in our hospital. ECRSI method was adopted to sort out the verification process and mode of drug bags for the
          unit  dose  formula  of  our  hospital  through  five  principles  of  eliminating,  combining,  rearranging,  simplifying  and  increasing,  and
          the  hardware  series  problem  and  the  problem  of  excessive  system  false-positive  proportion  were  optimized.  The  drug  bags  for  the
          unit  dose  formula  were  randomly  selected  from  10  wards,  the  efficiency  and  external  error  rates  of  manual  check  and  automatic
          checking  mode  before  and  after  optimization  were  compared,  and  the  false-positive  reporting  failure  in  automatic  checking  mode
          was  also  compared  before  and  after  optimization.  RESULTS  After  the  establishment  of  the  automatic  checking  mode  of  the  unit
          dose formula for oral drugs, the average checking time of drug bags was significantly shorter than that of manual checking mode in
          the  other  8  wards  except  for  cardiovascular  and  renal  departments (P<0.05).  After  the  optimization  of  the  automatic  checking
          mode, the average checking time of drug bags in all wards was significantly shorter than that in manual checking mode (P<0.05).
          Compared with before optimization of the automatic checking mode, the average checking time of drug bags was shortened by 0.43
          s,  and  the  average  checking  time  of  drug  bags  in  half  of  the  wards  was  shortened  significantly (P<0.05). At  the  same  time,  the
          false-positive proportion decreased from 96.83% before optimization to 92.76% after optimization (P<0.05). The external error rate
          dropped  from  0.039‰  in  manual  checking  mode  to  0.019‰  before  optimization  and  0.015‰  after  optimization (P<0.05).

          CONCLUSIONS  Based  on  ECRSI  method,  the  automatic  checking  mode  for  the  unit  dose  dispensing  system  of  oral  drugs  can
          effectively reduce the average checking time of drug bags, reduce external error and improve the work efficiency of pharmacists.
          KEYWORDS     unit dose dispensing system; ECRSI; automatic checking mode; manual checking mode; oral drugs



                                                                  单 剂 量 配 方 制(unit  dose  dispensing  system,
              *第一作者 主管药师,硕士。研究方向:药事管理、循证药学。
                                                              UDDS),又称为单元调剂或单剂量配方,即调剂人员把
          E-mail:13661350431@163.com
                                                              患者所服用的各种固体制剂按照单次服用剂量,借助
              # 通信作者 主任药师,硕士。研究方向:药事管理、药学质控。E-
          mail:13641066540@163.com                            全自动单剂量药品分包机(automatic medicine packing


          · 2018 ·    China Pharmacy  2023 Vol. 34  No. 16                            中国药房  2023年第34卷第16期
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