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参数赋值法在我院肠外营养液处方审核中的应用
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                *
          康 健 ,聂会娟,陈晓旭,钞艳惠,周晓燕,乔高星,刘胜利,杜书章(郑州大学第一附属医院药学部,郑州
                                                                        #
          450052)

          中图分类号  R952      文献标志码  A      文章编号  1001-0408(2022)22-2807-05
          DOI  10.6039/j.issn.1001-0408.2022.22.24


          摘  要  目的  为提高审方药师的工作效率、保障患者安全使用肠外营养液提供参考。方法  在静脉用药调配中心(PIVAS)
          MATE系统上开发肠外营养液审方模块,依据肠外营养液药品说明书及相关资料,对肠外营养液处方的审方模块进行参数赋值,
          设置阈值及计算公式,由系统自动对处方进行判定。统计我院2020年1-8月和2022年1-8月的肠外营养液不适宜处方类型和
          数量,对肠外营养液审方模块应用前后的不适宜处方审出率进行比较。结果  该模块实现了肠外营养液的离子浓度、热氮比、糖脂
          比、葡萄糖浓度、糖胰比、复方制剂最大用量、必须搭配使用的药品、配伍禁忌、重复用药、年龄限制等基础属性参数和自定义参数
          的信息化审核,大大缩短了审方时间,原来2人审核100张处方大约需要33 min,审方模块上线后只需要6 s;与2020年1-8月相
          比,2022年1-8月的肠外营养液不适宜处方平均审出率由0.582%提升至1.416%(P<0.05)。结论  我院利用参数赋值法建立的
          肠外营养液审方模块,大大减少了药师漏审、错审的现象,降低了肠外营养液处方的配置风险,减轻了审方药师的工作压力,保障
          了患者的用药安全。
          关键词  肠外营养液;处方审核;参数赋值法;工作效率;合理用药


          Application  of  parameter  assignment  method  in  the  review  of  parenteral  nutrition  prescription  in  our
          hospital
          KANG Jian,NIE Huijuan,CHEN Xiaoxu,CHAO Yanhui,ZHOU Xiaoyan,QIAO Gaoxing,LIU Shengli,DU
          Shuzhang(Dept. of Pharmacy,the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China)

          ABSTRACT   OBJECTIVE To provide reference for improving the working efficiency of prescription review for pharmacists and
          ensuring the safe use of parenteral nutrition solution in patients. METHODS The review module of parenteral nutrition prescription
          was developed with the pharmacy intravenous admixture services(PIVAS) MATE system. According to the instructions and relevant
          information of parenteral nutrition solution, the parameters to the review module for parenteral nutrition solution prescriptions were
          assigned, thresholds and calculation formulas were set, and the prescription was automatically determined by the system. The type
          and quantity of the inappropriate prescriptions of parenteral nutrition solution in our hospital from January to August 2020 and from
          January  to August  2022  were  counted,  and  the  review  efficiency  of  inappropriate  prescriptions  was  compared  before  and  after  the
          application  of  the  review  module  of  parenteral  nutrition  solution  prescription. RESULTS  The  module  realized  the  informatized
          review  of  basic  attribute parameters  and  custom  parameters  of  parenteral nutrition  solution  prescription,  such  as  ion  concentration,
          ratio  of  heat  to  nitrogen,  ratio  of  sugar  to  lipid,  glucose  concentration,  ratio  of  sugar  to  insulin,  maximum  dosage  of  compound
          preparation,  necessary  drug  collocation,  incompatibility,  repeated  drug  use,  age  limit,  etc. The  module  also  shortened  the  review
          time  greatly.  It  took  about  33  minutes  for  two  pharmacists  to  review  100  prescriptions,  and  only  took  6  seconds  after  the  module
          went  online.  Compared  with  January  to  August  in  2020,  the  average  approval  rate  of  inappropriate  prescriptions  for  parenteral
          nutrition  solution  increased  from  0.582%  to  1.416%  during  the  corresponding  period  in  2022 (P<0.05). CONCLUSIONS  The
          review  module  of  parenteral  nutrition  solution  prescription  established  by  parameter  assignment  method  in  our  hospital  can  greatly
          reduce  the  phenomenon  of  missed  and  wrong  review  by  pharmacists,  reduce  the  risk  of  parenteral  nutrition  solution  dispensing,
                                                             reduces  the  work  pressure  of  pharmacists  reviewing
             Δ 基金项目 河南省医学科技攻关计划(联合共建)项目(No.
          LHGJ20190277)                                      prescriptions, and ensures the drug safety of patients.
             * 第一作者 主 管 药 师 。 研 究 方 向 :医 院 药 学 。 电 话 :0371-  KEYWORDS     parenteral  nutrition  solution;  prescription
          66862018。E-mail:241340670@qq.com
                                                             review;  parameter  assignment  method;  work  efficiency;
             # 通信作者 主任药师。研究方向:循证医学、药物经济学。电话:
          0371-67966013。E-mail:dushuzhang911@163.com         rational drug use


          中国药房  2022年第33卷第22期                                              China Pharmacy  2022 Vol. 33  No. 22    · 2807 ·
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