Page 49 - 《中国药房》2022年9期
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breakdown in diabetes-associated cognitive decline[J]. J mouse brain microglia but not in astrocytes[J]. PLoS One,
Neuroimmunol,2022,362:577763. 2015,10(6):e0130624.
[12] 张婧涵,王光函,邹桂欣.高效液相色谱法同时测定癫痫 [25] THUBRON E B,ROSA H S,HODGES A,et al. Regional
清颗粒中3组分含量[J].中国药业,2014,23(18):46-47. mitochondrial DNA and cell-type changes in post-mortem
[13] 姜鸿,王光涵,张颖,等.癫痫清颗粒中β-细辛醚在大鼠体 brains of non-diabetic Alzheimer’s disease are not present
内的药代动力学研究[J].时珍国医国药,2014,25(12): in diabetic Alzheimer’s disease[J]. Sci Rep,2019,9(1):
2892-2894. 11386.
[14] 张婧涵,王光函,邹桂欣.癫痫清颗粒中α-细辛醚含量测 [26] WEISS N,MILLER F,CAZAUBON S,et al. The blood-
定方法研究[J].中国中医药信息杂志,2014,21(10): brain barrier in brain homeostasis and neurological diseases
83-85. [J]. Biochim Biophys Acta,2009,1788(4):842-857.
[15] 李荧,杨彩瑜,贾冬,等.癫痫清颗粒对阿尔茨海默病模型 [27] ZHANG F,LI Y,TANG Z S,et al. Proliferative and sur-
小鼠血脑屏障的影响[J]. 中成药,2021,43(2):497-502. vival effects of PUMA promote angiogenesis[J]. Cell Rep,
[16] QI Y,JI X F,CHI T Y,et al. Xanthoceraside attenuates 2012,2(5):1272-1285.
amyloid β peptide1-42-induced memory impairments by [28] CAHILOG Z,ZHAO H L,WU L Z,et al. The role of neu-
reducing neuroinflammatory responses in mice[J]. Eur J trophil NETosis in organ injury:novel inflammatory cell
Pharmacol,2018,820:18-30. death mechanisms[J]. Inflammation,2020,43(6):2021-
[17] 李晓晖,王艳霞,董依依,等.姜黄素衍生物Cur20通过抑 2032.
制乙酰胆碱酯酶改善阿尔茨海默病小鼠的记忆和认知 [29] PARRA-ANGUITA L,SÁNCHEZ-GARCÍA I,DEL
能力实验研究[J].药物评价研究,2022,45(3):449-454. PINO-CASADO R,et al. Measuring knowledge of
[18] 齐越,李荧,贾冬,等.癫痫清颗粒对阿尔茨海默病小鼠学 Alzheimer’s:development and psychometric testing of
习记忆能力的影响和作用机制研究[J].中国现代医生, the UJA Alzheimer’s Care Scale[J]. BMC Geriatr,2019,
2021,59(32):34-39,193. 19(1):63.
[19] 尚立芝,毛梦迪,许二平,等.柴胡加龙骨牡蛎汤对抑郁大 [30] TUERXUN M,MUHDA A,YIN L X.The molecular
鼠海马组织 PI3K/Akt/GSK3β/β-catenin 信号通路的影 mechanisms of signal pathway activating effect of E2F-1/
响[J].中国实验方剂学杂志,2020,26(23):12-19. NF-κB/GSK-3β on cognitive dysfunction of Alzheimer
[20] YANG Y,WANG H N,KOUADIR M,et al. Recent ad- rats[J]. Bioengineered,2021,12(2):10000-10008.
vances in the mechanisms of NLRP3 inflammasome acti- [31] YAN J H,LI L,KHATIBI N H,et al. Blood-brain barrier
vation and its inhibitors[J]. Cell Death Dis,2019,10(2): disruption following subarchnoid hemorrhage may be fa-
128. ciliated through PUMA induction of endothelial cell apop-
[21] BAKHSHI S,SHAMSI S. MCC950 in the treatment of tosis from the endoplasmic Reticulum[J]. Exp Neurol,
NLRP3-mediated inflammatory diseases:latest evidence 2011,230(2):240-247.
and therapeutic outcomes[J]. Int Immunopharmacol, [32] 白莹. miR-143 调节血脑屏障完整性及其调控机制[D].
2022,106:108595. 南京:东南大学,2018.
[22] COLL R C,HILL J R,DAY C J,et al. MCC950 directly [33] IBRAHIM S S,ABO ELSEOUD O G,MOHAMEDY M H,
targets the NLRP3 ATP-hydrolysis motif for inflamma- et al. Nose-to-brain delivery of chrysin transfersomal and
some inhibition[J]. Nat Chem Biol,2019,15(6):556-559. composite vesicles in doxorubicin-induced cognitive im-
[23] FEKETE C,VASTAGH C,DÉNES Á,et al. Chronic amy- pairment in rats:insights on formulation,oxidative stress
loid β oligomer infusion evokes sustained inflammation and TLR4/NF-κB/NLRP3 pathways[J]. Neuropharmacology,
and microglial changes in the rat hippocampus via 2021,197:108738.
NLRP3[J]. Neuroscience,2019,405:35-46. (收稿日期:2022-01-29 修回日期:2022-04-05)
[24] GUSTIN A,KIRCHMEYER M,KONCINA E,et al. (编辑:林 静)
NLRP3 inflammasome is expressed and functional in
中国药房 2022年第33卷第9期 China Pharmacy 2022 Vol. 33 No. 9 ·1067 ·