Page 130 - 《中国药房》2021年10期

·药师与药学服务·

中药饮片合理用药软件知识库构建思路探讨 Δ

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周 鹏 ，凌 霄 ，刘瑞新 ，李学林 ，张 博 ，桂新景（1.河南中医药大学第一附属医院药学部，郑州
450000；2.郑州众生实业集团有限公司，郑州 450001）
中图分类号 R95；R969.3 文献标志码 A 文章编号 1001-0408（2021）10-1272-05
DOI 10.6039/j.issn.1001-0408.2021.10.19

摘 要 目的：为中药饮片合理用药软件知识库的构建和软件开发提供参考。方法：查阅近年来合理用药软件和中药饮片合理用
药方面的文献，分析中药饮片合理用药的临床特点与现有合理用药软件在中药饮片合理用药检测方面的特点、不足，梳理、归纳总
结中药饮片合理用药软件知识库构建的整体思路、核心内容及难点。结果与结论：中药饮片的临床应用以“辨证施治”为主要依
据，体现辨证、治法、选方与用药的统一，故对于中药饮片临床应用合理性的考量不能一味地模仿化学药的评价方式。目前的合理
用药软件整体设计未能基于中医药理论体系，在中药饮片合理用药审查方面尚不够全面、成熟，且缺少能满足中药饮片合理用药
要求的知识库。因此，应以中医药理论体系为指导，构建一套能满足中药饮片“理法方药”使用一致性评价要求的知识库，其内容
应该包括患者信息收集、疾病及证型等相关知识库建设、中药饮片炮制品的选择、临证加减、中药饮片品种遴选禁忌、配伍禁忌、联
合应用中成药或化学药、中药饮片用药剂量、处方每剂的总剂量及药味数量、特殊煎煮药物、用药方法及给药频次等。中药饮片合
理用药软件的开发仍存在疾病及证型等相关知识库建设和临证加减的合理性判定困难等难点。
关键词 中药饮片；合理用药；辨证施治；合理用药软件；知识库

Exploration on the Construction Ideas of Software Knowledge Base for Rational Use of TCM Decoction
Pieces
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ZHOU Peng ，LING Xiao ，LIU Ruixin ，LI Xuelin ，ZHANG Bo ，GUI Xinjing（1. Dept. of Pharmacy，the
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First Affiliated Hospital of Henan University of TCM，Zhengzhou 450000，China；2. Zhengzhou Zhongsheng
Industrial Group Co.，Ltd.，Zhengzhou 450001，China）
ABSTRACT OBJECTIVE：To provide reference for the construction and software development of knowledge base for rational
use of TCM decoction pieces. METHODS：By reviewing the literatures on rational drug use software and TCM decoction pieces in
recent years， the clinical characteristics of rational drug use of TCM decoction pieces as well as the characteristics and
shortcomings of existing rational drug use software in the detection of rational drug use of TCM decoction pieces were analyzed，
and the core contents and difficulties in the construction of knowledge base of rational drug use software of TCM decoction pieces
were summarized. RESULTS & CONCLUSIONS：Clinical application of TCM decoction pieces was mainly based on“syndrome
differentiation”， which reflected the unity of dialectics， treatment， prescription selection and medication. Therefore， the
consideration of the rationality of clinical use of TCM decoction pieces could not blindly imitate the evaluation method of chemical
medicine. Current rational drug use software was not based on the theoretical system of traditional Chinese medicine，and it was
not comprehensive and mature in the aspect of rational drug use review of TCM decoction pieces，and lacks the knowledge base
that could meet the requirements of rational use of TCM decoction pieces. Therefore，it is necessary to construct a set of knowledge
base which can meet the evaluation requirements of“consistency of principle，method and prescription use”of TCM decoction
pieces under the guidance of TCM theoretical system. Its contents include that patient information collection，construction of
knowledge base related to diseases and syndromes，selection of processed products of TCM decoction pieces，addition and
Δ 基金项目：国家重点研发计划中医药现代化重点专项项目 subtraction of clinical symptoms，selection taboo of varieties
（No.2017YFC1703400） of TCM decoction pieces， compatibility taboo， combined
＊副主任药师，硕士。研究方向：临床药学与药学信息化。电话： application of Chinese patent medicine or chemical medicine，
0371-66245274。E-mail：15890617667@139.com dosage of TCM decoction pieces， total dosage and taste
# 通信作者：副主任药师，博士。研究方向：中药饮片临床应用现
quantity of each prescription， special decoction drugs，
代化关键技术。电话：0371-66233562。E-mail：liuruixin7@163.com

·1272 · China Pharmacy 2021 Vol. 32 No. 10 中国药房 2021年第32卷第10期