Page 122 - 《中国药房》2021年第9期

roidal neovascularization and regulates endothelial cell [30] JOHNSON J，MAHER P，HANNEKEN A. The flavonoid，
function[J]. J Ocul Pharmacol Ther，2006，22（6）：425-430. eriodictyol，induces long-term protection in ARPE-19
[19] CHEN X，HAN R，HAO P，et al. Nepetin inhibits IL-1β in- cells through its effects on Nrf2 activation and phase 2
duced inflammation via NF-κ B and MAPKs signaling gene expression[J]. Invest Ophthalmol Vis Sci，2009，50
pathways in ARPE-19 cells[J]. Biomed Pharmacother， （5）：2398-2406.
2018，101：87-93. [31] SHEN Y，ZHANG W Y，CHIOU G C. Effect of narin-
[20] ZHANG T，MEI X，OUYANG H，et al. Natural flavonoid genin on NaIO3-induced retinal pigment epithelium de-
galangin alleviates microglia-trigged blood-retinal barrier generation and laser-induced choroidal neovascularization
dysfunction during the development of diabetic retinopa- in rats[J]. Int J Ophthalmol，2010，3（1）：5-8.
thy[J]. J Nutr Biochem，2019，65：1-14. [32] XIE X，FENG J，KANG Z，et al. Taxifolin protects RPE
[21] DU W，AN Y，HE X. Protection of kaempferol on oxida- cells against oxidative stress-induced apoptosis[J]. Mol
tive stress-induced retinal pigment epithelial cell da- Vis，2017，23：520-528.
mage[J/OL].Oxid Med Cell Longev，2018[2020-12-12]. [33] ZHU C，DONG Y，LIU H，et al. Hesperetin protects
https：//pubmed.ncbi.nlm.nih.gov/30584457/.DOI：10.1155/ against H2O2 triggered oxidative damage via upregulation
2018/1610751. of the Keap1-Nrf2/HO-1 signal pathway in ARPE-19
[22] ZHU Q，LIU M，HE Y，et al. Quercetin protect cigarette cells[J]. Biomed Pharmacother，2017，88：124-133.
smoke extracts induced inflammation and apoptosis in [34] GOPINATH B，LIEW G，KIFLEY A，et al. Dietary flavo-
RPE cells[J]. Artif Cells Nanomed Biotechnol，2019，47 noids and the prevalence and 15-y incidence of age-rela-
（1）：2010-2015. ted macular degeneration[J]. Am J Clin Nutr，2018，108
[23] HYTTI M，PIIPPO N，SALMINEN A，et al. Quercetin al- （2）：381-387.
leviates 4-hydroxynonenal-induced cytotoxicity and in- [35] WANG B，ZOU Y，YUAN Z L，et al. Genistein sup-
flammation in ARPE-19 cells[J]. Exp Eye Res，2015，132： pressed upregulation of vascular endothelial growth factor
208-215. expression by cobalt chloride and hypoxia in rabbit retinal
[24] WENG S，MAO L，GONG Y，et al. Role of quercetin in pigment epithelium cells[J]. J Ocul Pharmacol Ther，2003，
protecting ARPE-19 cells against H2O2 induced injury via 19（5）：457-464.
nuclear factor erythroid 2 like 2 pathway activation and [36] KINOSHITA S，NODA K，TAGAWA Y，et al. Genistein
endoplasmic reticulum stress inhibition[J]. Mol Med Rep， attenuates choroidal neovascularization[J]. J Nutr Bio-
2017，16（3）：3461-3468. chem，2014，25（11）：1177-1182.
[25] SHAO Y，YU H，YANG Y，et al. A solid dispersion of [37] WANG K，ZHU X，ZHANG K，et al. Puerarin inhibits
quercetin shows enhanced Nrf2 activation and protective amyloid β-induced NLRP3 inflammasome activation in
effects against oxidative injury in a mouse model of dry retinal pigment epithelial cells via suppressing ROS-de-
age-related macular degeneration[J/OL]. Oxid Med Cell pendent oxidative and endoplasmic reticulum stresses[J].
Longev，2019[2020-12-15]. https：//pubmed.ncbi.nlm.nih. Exp Cell Res，2017，357（2）：335-340.
gov/31781321/.DOI：10.1155/2019/1479571. [38] JHANJI V，LIU H，LAW K，et al. Isoliquiritigenin from
[26] ZHUANG P，SHEN Y，LIN B Q，et al. Effect of quercetin licorice root suppressed neovascularisation in experimen-
on formation of choroidal neovascularization（CNV）in tal ocular angiogenesis models[J]. Br J Ophthalmol，2011，
age-related macular degeneration（AMD）[J]. Eye Sci， 95（9）：1309-1315.
2011，26（1）：23-29. [39] CUI Y，LI Y，HUANG N，et al. Structure based modifica-
[27] LI F，BAI Y，ZHAO M，et al. Quercetin inhibits vascular tion of chalcone analogue activates Nrf2 in the human reti-
endothelial growth factor-induced choroidal and retinal an- nal pigment epithelial cell line ARPE-19[J]. Free Radic
giogenesis in vitro[J]. Ophthalmic Res，2015，53（3）： Biol Med，2020，148：52-59.
109-116. [40] MOINE E，BRABET P，GUILLOU L，et al. New lipophe-
[28] WANG J，GONG H M，ZOU H H，et al. Isorhamnetin pre- nol antioxidants reduce oxidative damage in retina pig-
vents H2O2 induced oxidative stress in human retinal pig- ment epithelial cells[J]. Antioxidants（Basel），2018，7
ment epithelial cells[J]. Mol Med Rep，2018，17（1）： （12）：197.
648-652. [41] MANSOOR S，GUPTA N，LUCZY-BACHMAN G，et al.
[29] ARUMUGAM B，PALANISAMY U D，CHUA K H，et al. Protective effects of memantine and epicatechin on cate-
Protective effect of myricetin derivatives from Syzygium chol-induced toxicity on Müller cells in vitro[J]. Toxicolo-
malaccense against hydrogen peroxide-induced stress in gy，2010，271（3）：107-114.
ARPE-19 cells[J]. Mol Vis，2019，25：47-59. [42] XU J，TU Y，WANG Y，et al. Prodrug of epigallocate-

·1136 · China Pharmacy 2021 Vol. 32 No. 9 中国药房 2021年第32卷第9期