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[35]  伊晓娇.基于系统生物学方法的丹红注射液抗阿霉素心                           matic and antimicrobial bioactivities[J]. PLoS One,2018.
             肌毒性作用机制研究[D].杭州:浙江大学,2019.                          DOI:10.1371/journal.pone.0190790.
        [36]  甘东浩,陈德强,冯蓬,等.基于网络药理学探讨骨碎补抗                    [48]  ASADBEGI M,YAGHMAEI P,SALEHI I,et al. Investi-
             骨质疏松的物质基础及作用机制[J].中国实验方剂学杂                          gation of thymol effect on learning and memory impair-
             志,2019,25(13):186-191.                              ment induced by intrahippocampal injection of amyloid
        [37]  BONESI M,MENICHINI F,TUNDIS R,et al. Acetylcho-    beta peptide in high fat diet-fed rats[J]. Metab Brain Dis,
             linesterase and butyrylcholinesterase inhibitory activity of  2017,32(3):827-839.
             Pinus species essential oils and their constituents[J]. J En-  [49]  ASADBEGI M,KOMAKI A,SALEHI I,et al. Effects of
             zym Inhib Med Chem,2010,25(5):622-628.              thymol on amyloid-β-induced impairments in hippocam-
        [38]  KIM K,BU Y,JEONG S,et al. Memory-enhancing effect  pal synaptic plasticity in rats fed a high-fat diet[J]. Brain
             of a supercritical carbon dioxide fluid extract of the nee-  Res Bull,2018. DOI:10.1016/j.brainresbull.2018.01.008.
             dles of Abies koreana on scopolamine-induced amnesia in  [50]  王涛.阿尔茨海默症 Ch4 脑区相关的遗传变异位点的识
             mice[J]. Biosci Biotech Biochem,2006,70(8):1821-    别与分析[D].哈尔滨:哈尔滨工业大学,2019.
             1826.                                          [51]  罗俊.石菖蒲-益智仁精油提取工艺及精油吸嗅给药对
        [39]  MOHANDAS E,RAJMOHAN V,RAGHUNATH B. Neu-            AD的作用研究[D].南昌:江西中医药大学,2019.
             robiology of Alzheimer’s disease[J]. Indian J Psychiatry,  [52]  XIE B,LI X,DONG XY,et al. Insight into the inhibition
             2009,51(1):55-61.                                   effect of acidulated serum albumin on amyloid β-protein
        [40]  ARPITA K,ASHISH K,BRYAN M,et al. A serine protea-  fibrillogenesis and cytotoxicity[J]. Langmuir,2014,30
             se KLK8 emerges as a regulator of regulators in memory:  (32):9789-9796.
             microtubule protein dependent neuronal morphology and  [53]  GU Z,ZHONG P,YAN Z. Activation of muscarinic recep-
             PKA-CREB signaling[J]. Sci Rep,2018. DOI:10. 1038/  tors inhibits beta-amyloid peptide-induced signaling in
             s41598-018-27640-6.                                 cortical slices[J]. J Biol Chem,2003,278(19):17546-
        [41]  汪亚楠,李思齐,岳一强,等.基于网络药理学的苓桂术甘                         17556.
             汤治疗阿尔茨海默病的潜在作用机制研究[J].中草药,                     [54]  毕丹蕾,文朗,熊伟,等.阿尔茨海默病的可能药物靶点和
             2019,50(23):5812-5122.                              临床治疗研究进展[J].中国药理学与毒理学杂志,2015,
        [42]  WATER BVD,ZOETEWEIJ JP,BONT HJD,et al. Role        29(4):507-536.
                            2+
             of mitochondrial Ca in the oxidative stress-induced dissi-  [55]  CHEE LY,CUMMING A. Polymorphisms in the choliner-
             pation of the mitochondrial membrane potential:studies in  gic receptors muscarinic(CHRM2 and CHRM3)genes
             isolated proximal tubular cells using the nephrotoxin 1,  and Alzheimer’s disease[J]. Avicenna J Med Biotechnol,
             2-dichlorovinyl-L-cysteine[J]. J Biol Chem,1994,269  2018,10(3):196-199.
             (20):14546-14552.                              [56]  QILING JI,XUEMEI WANG,CAI J. MiR-22-3p regu-
        [43]  胡倩,刘育铖,毛思宇,等.基于网络药理学对白术治疗阿                         lates amyloid β deposit in mice model of Alzheimer’s dis-
             尔茨海默症的机制探讨[J].中南药学,2020,18(3):                      ease by targeting mitogen-activated protein kinase 14[J].
             427-434.                                            Curr Neurovasc Res,2019,16(5):473-480.
        [44]  刘邵阳,白辰,徐竞男,等.基于网络药理学方法探索达原                    [57]  王晶,刘斌,薛慧,等.基于整合药理学平台的杜仲植物雌
             饮治疗发热作用机制[J].中国中医药信息杂志,2020,27                      激素类成分治疗 AD 的作用机制研究[J].现代中药研究
             (5):84-89.                                          与实践,2019,33(1):30-34.
        [45]  郁俊昌,唐牟尼,韩海英,等.阿尔茨海默病、血管性痴呆                    [58]  邝梓君,汤顺莉,黄雁,等.酸枣仁汤治疗失眠的有效成分
             及轻度认知障碍患者血浆脑源性神经营养因子浓度变                             预测与靶点通路分析[J].中华中医药杂志,2018,33(8):
             化[J].实用医学杂志,2013,29(9):1429-1431.                   3585-3590.
        [46]  SAMMI SR,TRIVEDI S,RATH SK,et al. 1-methyl-4-  [59]  秦亚彬.孕酮对Aβ所致神经元损伤的保护作用及其机制
             propan-2-ylbenzene from Thymus vulgaris attenuates cho-  研究[D].石家庄:河北医科大学,2015.
             linergic dysfunction[J]. Mol Neurobiol,2016,54(7):  [60]  孙爽.孕酮对 AD 细胞模型及动物模型神经再生的影响
             5468-5481.                                          及机制研究[D].石家庄:河北医科大学,2018.
        [47]  CUTILLAS AB,CARRASCO A,MARTINEZ-GUTIER-                    (收稿日期:2020-02-07  修回日期:2020-07-07)
             REZ R,et al. Thymus mastichina L. essential oils from                               (编辑:张元媛)
             Murcia(Spain):composition and antioxidant,antienzy-






        ·2100 ·  China Pharmacy 2020 Vol. 31 No. 17                                 中国药房    2020年第31卷第17期
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