Page 95 - 《中国药房》2026年9期
P. 95

联用;对于其他DOACs与三唑类抗真菌药的联用方案,                              Reporting System[J]. Int J Med Sci,2013,10(7):796-803.
          也应密切监测出血相关表现并及时调整抗凝或抗真菌                            [10]  NORÉN G N,SUNDBERG R,BATE A,et al. A statistical
          治疗方案。                                                   methodology  for  drug-drug  interaction  surveillance[J].
          参考文献                                                    Stat Med,2008,27(16):3057-3070.
                                                             [11]  THAKRAR B T,GRUNDSCHOBER S B,DOESSEGGER
          [ 1 ]  JOGLAR J A,CHUNG M K,ARMBRUSTER A L,et al.
                                                                  L. Detecting signals of drug-drug interactions in a sponta‐
              2023 ACC/AHA/ACCP/HRS  guideline  for  the  diagnosis
                                                                  neous reports database[J]. Br J Clin Pharmacol,2007,64
              and  management  of  atrial  fibrillation:a  report  of  the
                                                                 (4):489-495.
              American College of Cardiology/American Heart Associa‐
                                                             [12]  NOGUCHI Y,TACHI T,TERAMACHI H. Review of sta‐
              tion  Joint  Committee  on  clinical  practice  guidelines[J].  J
                                                                  tistical methodologies for detecting drug-drug interactions
              Am Coll Cardiol,2024,83(1):109-279.
                                                                  using spontaneous reporting systems[J]. Front Pharmacol,
          [ 2 ]  周强,臧月月,陶瑛瑛,等. 新型口服抗凝药对比华法林
                                                                  2019,10:1319.
              用于左心室血栓有效性和安全性的 Meta 分析[J]. 中国
                                                             [13]  LIU M,LIU W W,JIAO H M. Spontaneous hemothorax
              药房,2022,33(24):3034-3039.
                                                                  caused by concomitant low-dose rivaroxaban and itracona-
          [ 3 ]  FERRI N,COLOMBO E,TENCONI M,et al. Drug-drug
                                                                  zole  in  a  95-year-old  patient:case  report  and  literature
              interactions of direct oral anticoagulants (DOACs):from
                                                                  review[J]. J Int Med Res,2021,49(9):03000605211047712.
              pharmacological  to  clinical  practice[J].  Pharmaceutics,
                                                             [14]  HOLT A,STRANGE J E,RASMUSSEN P V,et al. Blee-
              2022,14(6):1120.
                                                                  ding risk following systemic fluconazole or topical azoles
          [ 4 ]  BRÜGGEMANN R J M,ALFFENAAR J C,BLIJLEVENS
                                                                  in  patients  with  atrial  fibrillation  on  apixaban,rivaroxa‐
              N M A,et al. Clinical relevance of the pharmacokinetic in‐
                                                                  ban,or  dabigatran[J].  Am  J  Med,2022,135(5):595-
              teractions of azole antifungal drugs with other coadminis‐
                                                                  602.e5.
              tered agents[J]. Clin Infect Dis,2009,48(10):1441-1458.
                                                             [15]  CHANG S H,CHOU I J,YEH Y H,et al. Association be‐
          [ 5 ]  WIGGINS B S,DIXON D L,NEYENS R R,et al. Select
                                                                  tween use of non-vitamin K oral anticoagulants with and
              drug-drug  interactions  with  direct  oral  anticoagulants
                                                                  without concurrent medications and risk of major bleeding
              JACC  review  topic  of  the  week[J].  J Am  Coll  Cardiol,
                                                                  in  nonvalvular  atrial  fibrillation[J].  JAMA,2017,318
              2020,75(11):1341-1350.
                                                                 (13):1250-1259.
          [ 6 ]  彭文星. 口服抗凝药物治疗管理路径专家共识[J]. 临床
                                                             [16]  SVALASTOGA M,LARSEN T L,BREKKE J,et al. Ef‐
              药物治疗杂志,2024,22(9):1-23.
                                                                  fect  of  drug  interactions  with  apixaban  on  clinical  out‐
          [ 7 ]  STEFFEL J,COLLINS R,ANTZ M,et al. 2021 European
                                                                  comes  in  cancer  patients  with  venous  thromboembolism
              heart rhythm association practical guide on the use of non-
                                                                  [J]. Front Oncol,2025,15:1520725.
              vitamin  K  antagonist  oral  anticoagulants  in  patients  with
                                                             [17]  AOKI N,ABE K,TOKUTOMI H,et al. Characteristics of
              atrial fibrillation[J]. Europace,2021,23(10):1612-1676.
                                                                  gastrointestinal  bleeding  while  taking  direct  oral  anticoagu-
          [ 8 ]  LI A,LI M K,CROWTHER M,et al. Drug-drug interac‐
                                                                  lants  in  patients  with  nonvalvular  atrial  fibrillation  and
              tions  with  direct  oral  anticoagulants  associated  with  ad‐
                                                                  differences  among  drugs:a  single-center  retrospective
              verse  events  in  the  real  world:a  systematic  review[J].
                                                                  cohort study[J]. J Clin Med,2025,14(1):95.
              Thromb Res,2020,194:240-245.
                                                                            (收稿日期:2026-01-23  修回日期:2026-03-27)
          [ 9 ]  SAKAEDA T,TAMON A,KADOYAMA  K,et  al.  Data
                                                                                                  (编辑:舒安琴)
              mining  of  the  public  version  of  the  FDA Adverse  Event
















          中国药房  2026年第37卷第9期                                                China Pharmacy  2026 Vol. 37  No. 9    · 1189 ·
   90   91   92   93   94   95   96   97   98   99   100