Page 134 - 《中国药房》2025年14期
P. 134
hibits myocardial fibrosis by regulating miR-489/MyD88/ [34] HE Y,LU X L,CHEN T,et al. Resveratrol protects
NF-κB pathway[J]. J Ginseng Res,2023,47(2):218-227. against myocardial ischemic injury via the inhibition of
[24] WEI N,ZHANG C C,HE H B,et al. Protective effect of NF- κB-dependent inflammation and the enhancement of
saponins extract from Panax japonicus on myocardial antioxidant defenses[J]. Int J Mol Med,2021,47(3):29.
infarction:involvement of NF-κB,SIRT1 and mitogen- [35] WU D M,WANG Y J,HAN X R,et al. Tanshinone ⅡA
activated protein kinase signalling pathways and inhibi‐ prevents left ventricular remodelling via the TLR4/
tion of inflammation[J]. J Pharm Pharmacol,2014,66 MyD88/NF- κB signalling pathway in rats with myocar‐
(11):1641-1651. dial infarction[J]. J Cell Mol Med,2018,22(6):3058-
[25] SHI H,ZHOU P,GAO G,et al. Astragaloside Ⅳ prevents 3072.
acute myocardial infarction by inhibiting the TLR4/ [36] CHAI R N,YE Z L,XUE W J,et al. Tanshinone ⅡA in-
MyD88/NF- κB signaling pathway[J]. J Food Biochem, hibits cardiomyocyte pyroptosis through TLR4/NF-κB p65
2021,45(7):e13757. pathway after acute myocardial infarction[J]. Front Cell
[26] CHENG S Y,YU P,YANG L,et al. Astragaloside Ⅳ en‐ Dev Biol,2023,11:1252942.
hances cardioprotection of remote ischemic conditioning [37] WU Y X,TU X,LIN G S,et al. Emodin-mediated protec-
after acute myocardial infarction in rats[J]. Am J Transl tion from acute myocardial infarction via inhibition of in‐
Res,2016,8(11):4657-4669. flammation and apoptosis in local ischemic myocardium
[J]. Life Sci,2007,81(17/18):1332-1338.
[27] YU J M,ZHANG X B,ZHANG Y N. Astragaloside at‐
[38] DUAN N,HOU A J,LUAN B,et al. Gambogic acid
tenuates myocardial injury in a rat model of acute myocar‐
exerts cardioprotective effects in a rat model of acute myo‐
dial infarction by upregulating hypoxia inducible factor-
cardial infarction through inhibition of inflammation,
1α and Notch1/Jagged1 signaling[J]. Mol Med Rep,2017,
iNOS and NF-κB/p38 pathway[J]. Exp Ther Med,2018,
15(6):4015-4020.
15(2):1742-1748.
[28] GE S M,WU S H,YIN Q,et al. Ecliptasaponin A protects
[39] HAN A B,LU Y D,ZHENG Q,et al. Qiliqiangxin attenu-
heart against acute ischemia-induced myocardial injury by
ates cardiac remodeling via inhibition of TGF- β1/Smad3
inhibition of the HMGB1/TLR4/NF-κB pathway[J]. J Eth‐
and NF-κB signaling pathways in a rat model of myocar‐
nopharmacol,2024,335:118612.
dial infarction[J]. Cell Physiol Biochem,2018,45(5):
[29] LI J H,YANG Y K,WANG H,et al. Baicalein amelio‐
1797-1806.
rates myocardial ischemia through reduction of oxidative
[40] LIU Y K,GUO S W,ZHANG Y Q,et al. Impact of Yiqi
stress,inflammation and apoptosis via TLR4/MyD88/
huoxue decoction on the relationship between remodeling
MAPKS/NF-κB pathway and regulation of Ca homeosta‐
2+
of cardiac nerves and macrophages after myocardial in‐
sis by L-type Ca channels[J]. Front Pharmacol,2022,13:
2+
farction in rats[J]. J Healthc Eng,2022,2022:4441603.
842723.
[41] TAN Y,BIE Y L,CHEN L,et al. Lingbao huxin pill alle‐
[30] LI X G,YUAN T Y,CHEN D,et al. Cardioprotective ef‐
viates apoptosis and inflammation at infarct border zone
fects of puerarin-Ⅴ on isoproterenol-induced myocardial
through SIRT1-mediated FOXO1 and NF-κB pathways in
infarction mice is associated with regulation of PPAR-γ/
rat model of acute myocardial infarction[J]. Chin J Integr
NF-κB pathway[J]. Molecules,2018,23(12):3322.
Med,2022,28(4):330-338.
[31] IDRUS H H,SUNARNO. Liquiritin protects against
[42] CHEN J R,WEI J,ORGAH J,et al. Cardioprotective ef‐
cardiac fibrosis after myocardial fibrosis after myocardial fect of Danhong injection against myocardial infarction in
infarction by inhibiting CCL5 expression and the NF-κB rats is critically contributed by microRNAs[J]. Evid Based
signaling pathway[J]. Drug Des Dev Ther,2023,17:3. Complement Alternat Med,2019,2019:4538985.
[32] LAI X X,ZHANG N,CHEN L Y,et al. Latifolin protects [43] YUAN G Z,HAN A B,WU J,et al. Baoyuan decoction
against myocardial infarction by alleviating myocardial and Taohong siwu decoction improve lung structural re‐
inflammatory via the HIF-1α/NF- κB/IL-6 pathway[J]. modeling in a rat model of myocardial infarction:possible
Pharm Biol,2020,58(1):1156-1166. involvement of suppression of inflammation and fibrosis
[33] LV F H,YIN H L,HE Y Q,et al. Effects of curcumin on and regulation of the TGF-β1/Smad3 and NF-κB pathways
the apoptosis of cardiomyocytes and the expression of NF- [J]. Biosci Trends,2018,12(5):491-501.
κB,PPAR-γ and Bcl-2 in rats with myocardial infarction (收稿日期:2025-03-10 修回日期:2025-06-23)
injury[J]. Exp Ther Med,2016,12(6):3877-3884. (编辑:邹丽娟)
· 1812 · China Pharmacy 2025 Vol. 36 No. 14 中国药房 2025年第36卷第14期