Page 17 - 《中国药房》2025年3期
P. 17

Docetaxel versus active symptom control for refractory oe‐  vanced,or  recurrent  gastric  cancer (JFMC45-1102)[J].
              sophagogastric adenocarcinoma (COUGAR-02):an open-  Int J Cancer,2017,140(1):188-196.
              label,phase  3  randomised  controlled  trial[J].  Lancet  On‐  [45]  VAN  CUTSEM  E,DI  BARTOLOMEO  M,SMYTH  E,
              col,2014,15(1):78-86.                               et al. Trastuzumab deruxtecan in patients in the USA and
          [37]  HIRONAKA S,UEDA S,YASUI H,et al. Randomized,      Europe  with  HER2-positive  advanced  gastric  or  gastro‐
              open-label,phase Ⅲ study comparing irinotecan with pa‐  esophageal junction cancer with disease progression on or
              clitaxel  in  patients  with  advanced  gastric  cancer  without   after  a  trastuzumab-containing  regimen  (DESTINY-
              severe peritoneal metastasis after failure of prior combina‐  Gastric02):primary and updated analyses from a single-
              tion chemotherapy using fluoropyrimidine plus platinum:  arm,phase  2  study[J].  Lancet  Oncol,2023,24(7):
              WJOG 4007 trial[J]. J Clin Oncol,2013,31(35):4438-  744-756.
              4444.                                          [46]  LI J,DENG Y H,ZHANG W J,et al. Subcutaneous enva‐
          [38]  HIGUCHI K,TANABE S,SHIMADA K,et al. Biweekly      folimab monotherapy in patients with advanced defective
              irinotecan plus cisplatin versus irinotecan alone as second-  mismatch repair/microsatellite instability high solid tumors
              line  treatment  for  advanced  gastric  cancer:a  randomised   [J]. J Hematol Oncol,2021,14(1):95.
              phase Ⅲ trial (TCOG GI-0801/BIRIP trial)[J]. Eur J Can‐  [47]  LI J,XU Y,ZANG A M,et al. Tislelizumab in previously
              cer,2014,50(8):1437-1445.                           treated,locally advanced unresectable/metastatic microsa-
          [39]  FUCHS  C  S,TOMASEK  J,YONG  C  J,et  al.  Ramuci‐  tellite  instability-high/mismatch  repair-deficient  solid  tu‐
              rumab monotherapy for previously treated advanced gas‐  mors[J]. Chung Kuo Yen Cheng Yen Chiu,2024,36(3):
              tric  or  gastro-oesophageal  junction  adenocarcinoma   257-269.
              (REGARD):an  international,randomised,multicentre,  [48]  QIN S K,LI J,ZHONG H J,et al. Serplulimab,a novel
              placebo-controlled,phase  3  trial[J].  Lancet,2014,383  anti-PD-1  antibody, in  patients  with  microsatellite
              (9911):31-39.                                       instability-high solid tumours:an open-label,single-arm,
          [40]  WILKE H,MURO K,VAN CUTSEM E,et al. Ramuci‐        multicentre,phase  Ⅱ  trial[J].  Br  J  Cancer,2022,127
              rumab plus paclitaxel versus placebo plus paclitaxel in pa‐  (12):2241-2248.
              tients with previously treated advanced gastric or gastro-  [49]  PENG Z,LIU T S,WEI J,et al. Efficacy and safety of a
              oesophageal  junction  adenocarcinoma (RAINBOW):a   novel  anti-HER2  therapeutic  antibody  RC48  in  patients
              double-blind,randomised phase 3 trial[J]. Lancet Oncol,  with  HER2-overexpressing,locally  advanced  or  meta‐
              2014,15(11):1224-1235.                              static gastric or gastroesophageal junction cancer:a single-
          [41]  XU  R  H,ZHANG Y  Q,PAN  H  M,et  al.  Efficacy  and   arm phase Ⅱ study[J]. Cancer Commun,2021,41(11):
              safety of weekly paclitaxel with or without ramucirumab   1173-1182.
              as  second-line  therapy  for  the  treatment  of  advanced       [50]  LI J,QIN S K,XU J M,et al. Randomized,double-blind,
              gastric  or  gastroesophageal  junction  adenocarcinoma   placebo-controlled  phase  Ⅲ  trial  of  apatinib  in  patients
              (RAINBOW-Asia):a  randomised,multicentre,double-    with  chemotherapy-refractory  advanced  or  metastatic  ad‐
              blind,phase  3  trial[J].  Lancet  Gastroenterol  Hepatol,  enocarcinoma of the stomach or gastroesophageal junction
              2021,6(12):1015-1024.                               [J]. J Clin Oncol,2016,34(13):1448-1454.
          [42]  WANG F,SHEN L,GUO W J,et al. Fruquintinib plus pa‐  [51]  SHITARA  K,BANG Y  J,IWASA  S,et  al. Trastuzumab
              clitaxel versus placebo plus paclitaxel for gastric or gastro‐  deruxtecan  in  previously  treated  HER2-positive  gastric
              esophageal  junction  adenocarcinoma:the  randomized   cancer[J]. N Engl J Med,2020,382(25):2419-2430.
              phase 3 FRUTIGA trial[J]. Nat Med,2024,30(8):2189-  [52]  SHEN L,CHEN P,LU J,et al. 172P trastuzumab deruxte‐
              2198.                                               can (T-DXd)  in  Chinese  patients (pts)  with  previously
          [43]  WEI X,LI J,YUAN H,et al. 1519P fruquintinib plus sin‐  treated HER2-positive locally advanced/metastatic gastric
              tilimab in patients (pts) with either treatment-naïve or pre‐  cancer (GC)  or  gastroesophageal  junction  adenocarci‐
              viously treated advanced gastric or gastroesophageal junc‐  noma (GEJA):primary  efficacy  and  safety  from  the
              tion (GEJ)  adenocarcinoma:results  from  a  multicenter,  phase  Ⅱ  single-arm  DESTINY-Gastric06 (DG06)  trial
              single-arm phase Ⅱ study[J]. Ann Oncol,2023,34:S856.  [J]. Ann Oncol,2023,34:S1542-S1543.
          [44]  NISHIKAWA  K,TAKAHASHI  T,TAKAISHI  H,et  al.   [53]  XU R H,RUAN D Y,ZHANG D S,et al. A phase 1 trial
              Phase  Ⅱ  study  of  the  effectiveness  and  safety  of  trastu‐  of   claudin   18.2-specific   antibody-drug   conjugate
              zumab  and  paclitaxel  for  taxane-  and  trastuzumab-naïve   CMG901 in patients with advanced gastric/gastroesopha‐
              patients  with  HER2-positive,previously  treated,ad‐  geal  junction  cancer[J].  J  Clin  Oncol,2023,41(36):


          中国药房  2025年第36卷第3期                                                 China Pharmacy  2025 Vol. 36  No. 3    · 267 ·
   12   13   14   15   16   17   18   19   20   21   22