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多学科协作诊疗持续药学监护系统在抗感染治疗患者中的应用
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谭 瑞 ,邹婷婷 ,孙 伟 ,彭礼波 ,苟静惠 (1.重庆医科大学附属巴南医院药剂科,重庆 401320;2.重庆医
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科大学附属巴南医院感染肝病科,重庆 401320;3.重庆医科大学附属巴南医院重症医学科,重庆 401320;
4.重庆医科大学附属第三医院药剂科,重庆 401120)
中图分类号 R95 文献标志码 A 文章编号 1001-0408(2024)23-2936-05
DOI 10.6039/j.issn.1001-0408.2024.23.16
摘 要 目的 探索多学科协作诊疗(MDT)持续药学监护系统在抗感染治疗患者中的应用效果。方法 本研究团队通过创新研
发一套MDT持续药学监护系统,将其应用于因感染经MDT后的抗感染治疗病例,以此实现持续用药监护模式创新。采用回顾性
分析方法,收集重庆医科大学附属巴南医院2021年1-10月重症医学科经传统抗感染MDT的150例患者为对照组,2022年1-10
月重症医学科因抗感染治疗实行MDT持续药学监护系统管理的130例患者为干预组。比较两组患者一般资料、持续跟踪管理情
况、抗感染治疗转归情况、药品不良反应发生情况、抗菌药物管理相关指标以及相关医务人员对临床药师药学服务的满意度。
结果 两组患者一般资料比较,差异均无统计学意义(P>0.05)。干预组患者持续跟踪管理比例明显高于对照组(P<0.01);且两
组持续跟踪管理发起人员、发起原因比较,差异均有统计学意义(P<0.05)。干预组抗感染治疗转归情况优于对照组,抗菌药物管
理相关指标(总住院时间、抗菌药物使用时间、药品总费用、抗菌药物使用量)低于对照组,医务人员综合满意度高于对照组,差异
均有统计学差异(P<0.05)。两组患者不良反应发生情况、抗菌药物费用差异均无统计学意义(P>0.05)。结论 本系统应用于经
MDT后的抗感染治疗患者,可实现以临床药师为核心的持续多学科跟踪管理,有利于提高MDT团队随访效率,提升临床药师药
学服务质量,改善治疗结局,促进临床合理使用抗菌药物。
关键词 多学科协作诊疗;持续药学监护系统;药学服务;抗菌药物;跟踪管理;满意度
Application of the multi-disciplinary treatment-based continuous pharmaceutical care system in patients
undergoing anti-infection treatment
TAN Rui ,ZOU Tingting ,SUN Wei ,PENG Libo ,GOU Jinghui (1. Dept. of Pharmacy, Banan Hospital
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Affiliated to Chongqing Medical University, Chongqing 401320, China;2. Dept. of Infectious Hepatology,
Banan Hospital Affiliated to Chongqing Medical University, Chongqing 401320, China;3. Dept. of Critical Care
Medicine, Banan Hospital Affiliated to Chongqing Medical University, Chongqing 401320, China;4. Dept. of
Pharmacy, the Third Affiliated Hospital of Chongqing Medical University, Chongqing 401120, China)
ABSTRACT OBJECTIVE To explore the application effects of the multi-disciplinary treatment (MDT)-based continuous
pharmaceutical care system in patients undergoing anti-infection treatment. METHODS This research team innovatively developed
an MDT continuous pharmaceutical care system, which was applied to cases of anti-infection treatment following MDT due to
infection, aiming to innovate the continuous medication supervision model. A retrospective analysis method was used to collect data
from 150 patients in the intensive care unit who underwent conventional anti-infection MDT consultations from January to October
2021 in Banan Hospital Affiliated to Chongqing Medical University, serving as the control group, and 130 patients in the intensive
care unit who were under the MDT continuous pharmaceutical care system from January to October 2022 were selected as the
intervention group. The general information of the patients, the information continuous tracking management, the outcomes of anti-
infection treatment, adverse drug reactions, antibacterial drug management indicators, and the degree of satisfaction of relevant
medical staff with the clinical pharmacists’ pharmaceutical services were compared between the two groups. RESULTS Comparison
of general information between the two groups showed no statistically significant differences (P>0.05). The proportion of
continuous tracking management in the intervention group was significantly higher than in the control group (P<0.01), and the
differences in the initiators and reasons for continuous tracking management between the two groups were statistically significant
(P<0.05). The intervention group had better outcomes in anti-infection treatment compared to the control group (P<0.05). The
antibacterial drug management indicators (total length of
Δ 基金项目 重庆市科卫联合医学科研项目(No.2022QNXM003)
* 第一作者 主 管 药 师 ,硕 士 。 研 究 方 向 :抗 感 染 。 E-mail: hospital stay, duration of antibacterial drug use, total drug
ruirui0615@163.com costs, and amount of antibacterial drugs used) in the
# 通信作者 主 管 药 师 ,硕 士 。 研 究 方 向 :抗 感 染 。 E-mail: intervention group were significantly lower than in the control
543207553@qq.com group, while overall degree of satisfaction among medical
· 2936 · China Pharmacy 2024 Vol. 35 No. 23 中国药房 2024年第35卷第23期