Page 132 - 《中国药房》2024年15期
P. 132

The effect of metformin on chemotherapy-induced toxici‐  diet with or without metformin in patients with advanced
               ties  in  non-diabetic  breast  cancer  patients:a  randomised   non-small  cell  lung  cancer[J].  Lung  Cancer,2021,151:
               controlled study[J]. Drug Saf,2023,46(6):587-599.   8-15.
          [37]  YANG J J,ZHOU Y L,XIE S D,et al. Metformin induces   [47]  WANG Z G,LU C H,ZHANG K J,et al. Metformin com‐
               ferroptosis  by  inhibiting  UFMylation  of  SLC7A11  in   bining  PD-1  inhibitor  enhanced  anti-tumor  efficacy  in
               breast cancer[J]. J Exp Clin Cancer Res,2021,40(1):206.  STK11 mutant lung cancer through AXIN-1-dependent in‐
          [38]  KIM H M,KANG M J,SONG S O. Metformin and cervi‐    hibition  of  STING  ubiquitination[J].  Front  Mol  Biosci,
               cal  cancer  risk  in  patients  with  newly  diagnosed  type  2   2022,9:780200.
               diabetes:a population-based study in Korea[J]. Endocrinol   [48]  ZHAO Y W,LUO Q M,MO J R,et al. Metformin in com‐
               Metab (Seoul),2022,37(6):929-937.                   bination with JS-K inhibits growth of renal cell carcinoma
          [39]  CHEN Y H,YANG S F,YANG C K,et al. Metformin in‐    cells via reactive oxygen species activation and inducing
               duces  apoptosis  and  inhibits  migration  by  activating  the   DNA breaks[J]. J Cancer,2020,11(13):3701-3712.
               AMPK/p53 axis and suppressing PI3K/AKT signaling in   [49]  HAMIEH L,MCKAY R R,LIN X,et al. Effect of metfor‐
               human  cervical  cancer  cells[J].  Mol  Med  Rep,2021,  min use on survival outcomes in patients with metastatic
               23(1):88.                                           renal cell carcinoma[J]. Clin Genitourin Cancer,2017,15
          [40]  XIA C L,LIU C,HE Z H,et al. Metformin inhibits cervi‐  (2):221-229.
               cal  cancer  cell  proliferation  by  modulating  PI3K/Akt-  [50]  LIU  M  H,ZHANG  Z,WANG  H,et  al.  Activation  of
               induced major histocompatibility complex class Ⅰ-related   AMPK by metformin promotes renal cancer cell prolifera‐
               chain A gene expression[J]. J Exp Clin Cancer Res,2020,  tion under glucose deprivation through its interaction with
               39(1):127.                                          PKM2[J]. Int J Biol Sci,2019,15(3):617-627.
          [41]  LU T,LI M,ZHAO M N,et al. Metformin inhibits human   [51]  GE L,WU Y G,WAN M,et al. Metformin increases sensi‐
               non-small cell lung cancer by regulating AMPK-CEBPB-  tivity  of  melanoma  cells  to  cisplatin  by  blocking
               PDL1  signaling  pathway[J].  Cancer  Immunol  Immuno‐  exosomal-mediated miR-34a secretion[J]. J Oncol,2021,
               ther,2022,71(7):1733-1746.                          2021:5525231.
          [42]  ZHU Z L,JIANG T,SUO H R,et al. Metformin poten-   [52]  MONTAUDIÉ  H,CEREZO  M,BAHADORAN  P,et  al.
               tiates the effects of anlotinib in NSCLC via AMPK/mTOR   Metformin monotherapy in melanoma:a pilot,open-label,
               and  ROS-mediated  signaling  pathways[J].  Front  Pharma‐  prospective,and multicentric study indicates no benefit[J].
               col,2021,12:712181.                                 Pigment Cell Melanoma Res,2017,30(3):378-380.
          [43]  ZHANG Q M,ZHENG J,WANG W,et al. The anticancer   [53]  AFZAL  M  Z,MERCADO  R  R,SHIRAI  K.  Efficacy  of
               effect of metformin combined with epidermal growth fac‐  metformin in combination with immune checkpoint inhibi‐
               tor  receptor  tyrosine  kinase  inhibitors  in  non-small  cell   tors (anti-PD-1/anti-CTLA-4)  in  metastatic  malignant
               lung cancer patients with or without type 2 diabetes melli‐  melanoma[J]. J Immunother Cancer,2018,6(1):64.
               tus:a systematic review and meta-analysis[J]. Oncol Ther,  [54]  CICCARESE C,IACOVELLI R,BUTI S,et al. Concur‐
               2022,10(2):363-375.                                 rent nivolumab and metformin in diabetic cancer patients:
          [44]  TSAKIRIDIS T,POND G R,WRIGHT J,et al. Metfor‐      is  it  safe  and  more  active? [J]. Anticancer  Res,2022,42
               min in combination with chemoradiotherapy in locally ad‐  (3):1487-1493.
               vanced non-small cell lung cancer:the OCOG-ALMERA   [55]  ZHUANG A,CHAI P W,WANG S Y,et al. Metformin
               randomized  clinical  trial[J].  JAMA  Oncol,2021,7(9):  promotes  histone  deacetylation  of  optineurin  and  sup‐
               1333-1341.                                          presses  tumour  growth  through  autophagy  inhibition  in
          [45]  SKINNER  H,HU  C,TSAKIRIDIS T,et al. Addition of   ocular melanoma[J]. Clin Transl Med,2022,12(1):e660.
               metformin  to  concurrent  chemoradiation  in  patients  with   [56]  ABDELMONEIM M,ABOALELA M A,NAOE Y,et al.
               locally  advanced  non-small  cell  lung  cancer:the  NRG-  The  impact  of  metformin  on  tumor-infiltrated  immune
               LU001 phase 2 randomized clinical trial[J]. JAMA Oncol,  cells:preclinical  and  clinical  studies[J].  Int  J  Mol  Sci,
               2021,7(9):1324-1332.                                2023,24(17):13353.
          [46]  LEE  Y,JOO  J,LEE  Y  J,et  al.  Randomized  phase  Ⅱ       (收稿日期:2023-11-17  修回日期:2024-06-14)
               study  of  platinum-based  chemotherapy  plus  controlled                          (编辑:胡晓霖)





          · 1922 ·    China Pharmacy  2024 Vol. 35  No. 15                            中国药房  2024年第35卷第15期
   127   128   129   130   131   132   133   134   135   136   137