Page 92 - 《中国药房》2024年12期

参考文献 [10] CHEN D Q，FENG Y L，CHEN L，et al. Poricoic acid A
[ 1 ] DAI P P，CHANG W F，XIN Z R，et al. Retrospective enhances melatonin inhibition of AKI-to-CKD transition
study on the influencing factors and prediction of hospita- by regulating Gas6/AxlNFκB/Nrf2 axis[J]. Free Radic
lization expenses for chronic renal failure in China based Biol Med，2019，134：484-497.
on random forest and LASSO regression[J]. Front Public [11] JIANG G P，LIAO Y J，HUANG L L，et al. Effects and
Health，2021，9：678276. molecular mechanism of pachymic acid on ferroptosis in
[ 2 ] YOUNIS N N，MOHAMED H E，SHAHEEN M A，et al. renal ischemia reperfusion injury[J]. Mol Med Rep，2021，
Potential therapeutic efficacy of pachymic acid in chronic 23（1）：63.
kidney disease induced in rats：role of Wnt/β-catenin/ [12] LI R，GUO Y J，ZHANG Y M，et al. Salidroside amelio‐
renin-angiotensin axis[J]. J Pharm Pharmacol，2022，74 rates renal interstitial fibrosis by inhibiting the TLR4/NF-
（1）：112-123. κB and MAPK signaling pathways[J]. Int J Mol Sci，
[ 3 ] ZHANG C Y，ZHU J Y，YE Y，et al. Erhuang formula 2019，20（5）：1103.
ameliorates renal damage in adenine-induced chronic [13] TANG P M，ZHANG Y Y，XIAO J，et al. Neural transcrip‐
renal failure rats via inhibiting inflammatory and fibrotic tion factor Pou4f1 promotes renal fibrosis via macrophage-
responses[J]. Biomedecine Pharmacother， 2017， 95： myofibroblast transition[J]. Proc Natl Acad Sci U S A，
520-528. 2020，117（34）：20741-20752.
[ 4 ] SECCIA T M，RIGATO M，RAVAROTTO V，et al. ROCK [14] GIFFORD C C，TANG J Q，COSTELLO A，et al. Nega‐
（RhoA/Rho kinase）in cardiovascular-renal pathophysio- tive regulators of TGF-β1 signaling in renal fibrosis；patho‐
logy：a review of new advancements[J]. J Clin Med，2020， logical mechanisms and novel therapeutic opportunities
9（5）：1328. [J]. Clin Sci，2021，135（2）：275-303.
[ 5 ] CHEN Y，HUANG C，DUAN Z B，et al. LncRNA NEAT1 [15] YIN Q，LIU H. Connective tissue growth factor and renal
accelerates renal fibrosis progression via targeting miR-31 fibrosis[J]. Adv Exp Med Biol，2019，1165：365-380.
and modulating RhoA/ROCK signal pathway[J]. Am J [16] KUPPE C，IBRAHIM M M，KRANZ J，et al. Decoding
Physiol Cell Physiol，2023，324（2）：C292-C306. myofibroblast origins in human kidney fibrosis[J]. Nature，
[ 6 ] 谢骏，王媛媛，李聚鑫，等 . 茯苓多糖调控 Rho-ROCK 信 2021，589（7841）：281-286.
号通路对心肌缺血再灌注损伤大鼠心肌细胞凋亡的影 [17] RUIZ-ORTEGA M，LAMAS S，ORTIZ A. Antifibrotic
响和机制研究[J]. 中国中药杂志，2023，48（23）：6434- agents for the management of CKD：a review[J]. Am J
6441. Kidney Dis，2022，80（2）：251-263.
XIE J，WANG Y Y，LI J X，et al. Effect and mechanism of [18] CHEN J H，CHEN C，BAO X B，et al. Effects of dexme‐
Poria cocos polysaccharides on myocardial cell apoptosis detomidine on the RhoA/ROCK/Nox4 signaling pathway
in rats with myocardial ischemia-reperfusion injury by in renal fibrosis of diabetic rats[J]. Open Med，2019，14：
regulating Rho-ROCK signaling pathway[J]. China J Chin 890-898.
Mater Med，2023，48（23）：6434-6441. [19] 张波涛，王雅蓉，张婷，等 . 甜菜碱调控 RhoA/ROCK 抑
[ 7 ] 朱晓婷，陈志强. 益气化湿通络方对实验性肾功能衰竭 制野百合碱致大鼠肺动脉高压[J]. 实用医学杂志，2023，
大鼠肾脏氧化应激损伤及纤维化的改善作用[J]. 中国应 39（15）：1876-1880.
用生理学杂志，2020，36（1）：67-72，97-98. ZHANG B T，WANG Y R，ZHANG T，et al. Betaine in‐
ZHU X T，CHEN Z Q. The improvement effects of Yiqi hibits monocrotaline-induced pulmonary hypertension in
huashi tongluo formula on oxidative stress and renal fibrosis rats by regulating RhoA/ROCK protein expression[J]. J
of experimental CRF rats[J]. Chin J Appl Physiol，2020， Pract Med，2023，39（15）：1876-1880.
36（1）：67-72，97-98. [20] SHI Z Z，WANG Q，ZHANG Y B，et al. Extracellular
[ 8 ] 李宏亮 . mTOR/P70S6K 信号通路在肾功能不全大鼠对 vesicles produced by bone marrow mesenchymal stem
比剂急性肾损伤中的作用研究[D]. 天津：天津医科大 cells attenuate renal fibrosis，in part by inhibiting the
学，2016. RhoA/ROCK pathway，in a UUO rat model[J]. Stem Cell
LI H L. Role of mTOR/P70S6K signaling pathway in Res Ther，2020，11（1）：253.
contrast-induced acute renal injury in rats with renal insuf‐ [21] YAN X X，ZHENG A D，ZHANG Z N，et al. Protective ef‐
ficiency[D]. Tianjin：Tianjin Medical University，2016. fect of pantoprazole against sepsis-induced acute lung and
[ 9 ] YANG K，LI W，BAI T，et al. Mindin deficiency alle- kidney injury in rats[J]. Am J Transl Res，2019，11（8）：
viates renal fibrosis through inhibiting NF-κB and TGF-β/ 5197-5211.
Smad pathways[J]. J Cell Mol Med，2020，24（10）：5740- （收稿日期：2023-12-15 修回日期：2024-05-07）
5750. （编辑：张元媛）

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