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外,免疫学和遗传学的最新进展阐明了固有免疫在ADs                                LI S H,WU Q F. The progress of the roles of gut flora in
          发病中的重要性。研究固有免疫和适应性免疫间的相                                  Th17/Treg axis balance and inflammatory bowel diseases
          互作用,特别是它们与肠道微生物群的关系,将有望为                                 [J]. Immunol J,2019,35(8):722-726.
          ADs的防治提供新的视野。                                       [13]  LÜHRS H,GERKE T,MÜLLER J G,et al. Butyrate in‐
          参考文献                                                     hibits  NF-kappaB  activation  in  lamina  propria  macro‐
                                                                   phages  of  patients  with  ulcerative  colitis[J].  Scand  J
          [ 1 ]  COOPER G S,BYNUM M L K,SOMERS E C. Recent
                                                                   Gastroenterol,2002,37(4):458-466.
               insights in the epidemiology of autoimmune diseases:im‐
                                                              [14]  BOPANNA S,ANANTHAKRISHNAN A N,KEDIA S,
               proved prevalence estimates and understanding of cluste-
                                                                   et al. Risk of colorectal cancer in Asian patients with ulcera-
               ring of diseases[J]. J Autoimmun,2009,33(3/4):197-207.
                                                                   tive  colitis:a  systematic  review  and  meta-analysis[J].
          [ 2 ]  ABDEL-WAHAB N,SHAH M,LOPEZ-OLIVO M A,et
                                                                   Lancet Gastroenterol Hepatol,2017,2(4):269-276.
               al. Use of immune checkpoint inhibitors in the treatment
                                                              [15]  LIU X M,ZHOU M X,DAI Z Z,et al. Salidroside alle-
               of  patients  with  cancer  and  preexisting  autoimmune  di-
               sease:a systematic review[J]. Ann Intern Med,2018,168  viates ulcerative colitis via inhibiting macrophage pyropto‐
              (2):121-130.                                         sis  and  repairing  the  dysbacteriosis-associated Th17/Treg
          [ 3 ]  MICHAUDEL  C,SOKOL  H.  The  gut  microbiota  at  the   imbalance[J]. Phytother Res,2023,37(2):367-382.
               service  of  immunometabolism[J].  Cell  Metab,2020,32  [16]  ZHANG R,ZHANG Q Q,CHEN Y N,et al. Combined
              (4):514-523.                                         treatment  with  Rg1  and  adipose-derived  stem  cells  alle-
          [ 4 ]  TORCHINSKY M B,BLANDER J M. T helper 17 cells:    viates DSS-induced colitis in a mouse model[J]. Stem Cell
               discovery,function,and physiological trigger[J]. Cell Mol   Res Ther,2022,13(1):272.
               Life Sci,2010,67(9):1407-1421.                 [17]  张彩,田志刚. ILC细胞与自身炎症性疾病[J]. 中国免疫
          [ 5 ]  LEE G R. The balance of Th17 versus Treg cells in auto‐  学杂志,2019,35(6):641-647.
               immunity[J]. Int J Mol Sci,2018,19(3):730.          ZHANG C,TIAN Z G. Innate lymphoid cells and inflam‐
          [ 6 ]  OUYANG W  J,KOLLS  J  K,ZHENG Y. The  biological   matory  diseases[J].  Chin  J  Immunol,2019,35(6):
               functions of T helper 17 cell effector cytokines in inflam‐  641-647.
               mation[J]. Immunity,2008,28(4):454-467.        [18]  DONG Y L,FAN H,ZHANG Z,et al. Berberine amelio‐
          [ 7 ]  OMENETTI S,PIZARRO T T. The Treg/Th17 axis:a dy‐  rates  DSS-induced  intestinal  mucosal  barrier  dysfunction
               namic balance regulated by the gut microbiome[J]. Front   through  microbiota-dependence  and  Wnt/β -catenin  path‐
               Immunol,2015,6:639.                                 way[J]. Int J Biol Sci,2022,18(4):1381-1397.
          [ 8 ]  BUNTE K,BEIKLER T. Th17 cells and the IL-23/IL-17   [19]  甘金刚,樊海南,张志强. 盐酸小檗碱对溃疡性结肠炎患
               axis  in  the  pathogenesis  of  periodontitis  and  immune-  者肠道菌群及免疫状态的影响[J]. 中国中西医结合消化
               mediated inflammatory diseases[J]. Int J Mol Sci,2019,20  杂志,2020,28(12):949-953.
              (14):3394.                                           GAN J G,FAN H N,ZHANG Z Q. Effects of chlorhexi‐
          [ 9 ]  KUROLAP A,ESHACH ADIV O,KONNIKOVA L,et al.        dine  hydrochloride  on  intestinal  flora  and  immune  status
               A unique presentation of infantile-onset colitis and eosino‐  in  patients  with  ulcerative  colitis[J].  Chin  J  Integr Tradit
               philic disease without recurrent infections resulting from a   West Med Dig,2020,28(12):949-953.
               novel homozygous CARMIL2 variant[J]. J Clin Immunol,  [20]  XIAO  Q  P,ZHONG Y  B,KANG  Z  P,et  al.  Curcumin
               2019,39(4):430-439.                                 regulates the homeostasis of Th17/Treg and improves the
          [10]  FASCHING P,STRADNER M,GRANINGER W,et al.           composition  of  gut  microbiota  in  type  2  diabetic  mice
               Therapeutic  potential  of  targeting  the  Th17/Treg  axis  in   with colitis[J]. Phytother Res,2022,36(4):1708-1723.
               autoimmune disorders[J]. Molecules,2017,22(1):134.  [21]  WANG Y J,LI Q M,ZHA X Q,et al. Dendrobium fim‐
          [11]  KAMADA N,SEO S U,CHEN G Y,et al. Role of the gut   briatum Hook polysaccharide ameliorates dextran-sodium-
               microbiota in immunity and inflammatory disease[J]. Nat   sulfate-induced  colitis  in  mice  via  improving  intestinal
               Rev Immunol,2013,13(5):321-335.                     barrier function,modulating intestinal microbiota,and re‐
          [12]  李思慧,吴巧凤. 肠道菌群对Th17/Treg免疫平衡和炎症                     ducing  oxidative  stress  and  inflammatory  responses[J].
               性肠病影响的研究进展[J]. 免疫学杂志,2019,35(8):                    Food Funct,2022,13(1):143-160.
               722-726.                                       [22]  WEN S T,HE L,ZHONG Z T,et al. Stigmasterol restores


          · 2554 ·    China Pharmacy  2023 Vol. 34  No. 20                            中国药房  2023年第34卷第20期
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