Page 120 - 《中国药房》2023年14期

·综述·

国内外中药酒制相关研究的可视化分析
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商 杰 ，易海燕 ，刘明贵 ，张普照 ，张金莲 （1.江西中医药大学药学院，南昌 330004；2.江西景德中药股份
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有限公司，江西 景德镇 333000）
中图分类号 R283 文献标志码 A 文章编号 1001-0408（2023）14-1774-07
DOI 10.6039/j.issn.1001-0408.2023.14.21

摘 要 目的 分析中药酒制的研究现状和研究热点，为中药酒制的未来研究提供参考。方法 检索中国知网和Web of Science核
心合集数据库中有关中药酒制研究的文献，运用VOSviewer 1.6.18及CiteSpace 6.1.R2软件对核心作者、研究机构及关键词等内容
进行可视化分析。结果 经筛选，最终纳入中文文献962篇，英文文献57篇。2000－2022年间，有关中药酒制的中、英文文献发文
量总体呈上升趋势，张学兰、Cai B C（蔡宝昌）分别是中、英文文献发文量最多的作者；研究机构主要为中医药类高校，成都中医药
大学、南京中医药大学分别是中、英文文献发文量最多的研究机构；中、英文文献关键词分析显示，中药酒制的研究内容主要集中
在酒制品种、化学成分、酒制工艺、质量标准等方面，响应面法、色度值、代谢组学及作用机制是当前的研究热点。结论 中药酒制
的相关研究仍处于发展时期，利用响应面法优选酒制工艺、利用代谢组学结合其他组学等相关技术揭示中药酒制药效作用机制仍
是未来的发展趋势。今后应进一步加强机构间的合作，同时应加强辅料用酒的相关研究，并建立相关酒制品种的工艺及质量标
准，利用好现代化分析手段研究中药酒制增效机制，从而推进中药酒制的现代化、国际化进程。
关键词 酒制；酒炙；酒蒸；文献计量学；VOSviewer；CiteSpace；可视化分析

Visualization analysis of related research on wine processing of Chinese medicine at home and abroad
SHANG Jie ，YI Haiyan ，LIU Minggui ，ZHANG Puzhao ，ZHANG Jinlian（1. School of Pharmacy， Jiangxi
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University of Chinese Medicine， Nanchang 330004， China；2. Jiangxi Jingde Traditional Chinese Medicine Co.，
Ltd.， Jiangxi Jingdezhen 333000， China）
ABSTRACT OBJECTIVE To analyze the research status and hotspots of wine processing of Chinese medicine， and to provide
reference for its related research. METHODS Related literature about wine processing research in Chinese medicine was retrieved
from CNKI and Web of Science （WOS）. VOSviewer 1.6.18 and CiteSpace 6.1.1R2 software were used to visualize the core
authors， research institutions， keywords， and other contents. RESULTS A total of 962 Chinese literature and 57 English literature
were included in the study. In total， the trend in the amount of Chinese and English literature was on the rise during 2000-2022.
The analysis of the authors showed that ZHANG Xuelan and CAI Baochang had the most publications in Chinese and English
literature. Research institutions were mainly Chinese medicine universities， and Chengdu University of Chinese Medicine and
Nanjing University of Chinese Medicine were the research institutions with the largest number of Chinese and English literature
published. The analysis of keywords in Chinese and English literature showed that the wine-processing research of Chinese medicine
mainly focused on wine-processed varieties， chemical constituents， wine-processed process， and quality standards. Response
surface method， chroma value， metabolomics， and action mechanism had become current research hotspots. CONCLUSIONS The
related research of wine processing for Chinese medicine is still in the development period. In the future， the response surface
method to optimize the wine-processed process and the combination of metabolomics with related technologies of other omics to
reveal the pharmacodynamic mechanism of wine processing for Chinese medicine is still the future development trend. In the
future， cooperation between institutions should be further strengthened， and research on the use of excipients and alcohol should
be strengthened. Modern analytical methods should be utilized to enhance the efficiency of wine processing for Chinese medicine，
thereby promoting the modernization and internationalization of wine processing for Chinese medicine.
KEYWORDS wine-processed； stir-frying with wine； wine

Δ 基金项目 国家重点研发计划专项课题（No.2018YFC1707206）； steam-processed； bibliometrics； VOSviewer； CiteSpace；
江西省“双千计划”项目（No.S2019CXTD2300）；江西省高水平本科教 visualization analysis
学团队建设项目（No.2022114）
＊第一作者 硕士研究生。研究方向 ：中药炮制学。E-mail：
中药酒制是在中医药理论的指导下，将适量的辅料
shangjie1124@163.com
用酒加入到药材中，再经过炙、炖、蒸、淬等方法加工处
# 通信作者 教授，博士生导师。研究方向：中药学及中药炮制学。
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E-mail：jxjzzjl@163.com 理出满足中医临床用药要求的一种中药炮制技术 ，因

· 1774 · China Pharmacy 2023 Vol. 34 No. 14 中国药房 2023年第34卷第14期