Page 132 - 《中国药房》2025年5期
P. 132
[ 3 ] HU C H,YAN Q L,ZHANG Y,et al. Influence mecha‐ fluence of poloxamer 188 on anti-inflammatory and anal‐
nism of drug-polymer compatibility on humidity stability gesic effects of diclofenac-loaded nanoemulsion:formula‐
of crystalline solid dispersion[J]. Pharmaceuticals (Ba‐ tion,optimization and in vitro/in vivo evaluation[J]. J
sel),2023,16(12):1640. Pharm Sci,2023,112(12):3197-3208.
[ 4 ] HAN M J,ZOU Z Z. Enabling a novel solvent method on [16] SEDLARIKOVA J,JANALIKOVA M,EGNER P,et al.
albendazole solid dispersion to improve the in vivo bioa- Poloxamer-based mixed micelles loaded with thymol or
vailability[J]. Eur J Pharm Sci,2024,196:106751. eugenol for topical applications[J]. ACS Omega,2024,9
[ 5 ] TRENKENSCHUH E,BLATTNER S M,HIRSH D,et al. (22):23209-23219.
Development of ternary amorphous solid dispersions [17] ZARRINTAJ P,RAMSEY J D,SAMADI A,et al. Polo-
manufactured by hot-melt extrusion and spray-drying: xamer:a versatile tri-block copolymer for biomedical
comparison of in vitro and in vivo performance[J]. Mol applications[J]. Acta Biomater,2020,110:37-67.
Pharm,2024,21(3):1309-1320. [18] WHITE J M,CALABRESE M A. Impact of small mo-
[ 6 ] SOLANKI N G,LAM K,TAHSIN M,et al. Effects of sur‐ lecule and reverse poloxamer addition on the micellization
factants on itraconazole-HPMCAS solid dispersion pre‐ and gelation mechanisms of poloxamer hydrogels[J].
pared by hot-melt extrusion Ⅰ :miscibility and drug re‐ Colloids Surf A Physicochem Eng Asp,2022,638:
lease[J]. J Pharm Sci,2019,108(4):1453-1465. 128246.
[ 7 ] 田萌,李其彬,徐慧,等. 热熔挤出技术在生产洛索洛芬 [19] NGUYEN V T,DOAN P,NGUYEN D T,et al. Effect of
钠凝胶制剂中的应用[J]. 中国药学杂志,2023,58(9): targeting ligand designation of self-assembly chitosan-
799-806. poloxamer nanogels loaded paclitaxel on inhibiting MCF-
TIAN M,LI Q B,XU H,et al. Loxoprofen sodium gels 7 cancer cell growth[J]. J Biomater Sci Polym Ed,2022,
prepared by hot melt extrusion technology[J]. Chin Pharm 33(4):426-442.
J,2023,58(9):799-806. [20] ORASUGH J T,DUTTA S,DAS D,et al. Sustained re‐
[ 8 ] PISAY M,NAVTI P D,RAO V,et al. Investigation of lease of ketorolac tromethamine from poloxamer 407/cel‐
drug-polymer miscibility and design of ternary solid dis‐ lulose nanofibrils graft nanocollagen based ophthalmic
persions for oral bioavailability enhancement by hot melt formulations[J]. Int J Biol Macromol,2019,140:441-453.
extrusion[J]. J Drug Deliv Sci Technol,2023,90:105107. [21] PENG X J,DING C B,ZHAO Y C,et al. Poloxamer 407
[ 9 ] VASCONCELOS T,PREZOTTI F,ARAÚJO F,et al. and hyaluronic acid thermosensitive hydrogel-encapsu-
Third-generation solid dispersion combining soluplus and lated ginsenoside Rg3 to promote skin wound healing[J].
poloxamer 407 enhances the oral bioavailability of res- Front Bioeng Biotechnol,2022,10:831007.
veratrol[J]. Int J Pharm,2021,595:120245. [22] LIN Y J,CHANG CHIEN B Y,LEE Y H. Injectable and
[10] ESSA E,AMIN M,SULTAN A,et al. Hot melt extrusion thermoresponsive hybrid hydrogel with antibacterial,anti-
for enhanced dissolution and intestinal absorption of hy‐ inflammatory,oxygen transport,and enhanced cell growth
drochlorothiazide[J]. J Drug Deliv Sci Technol,2023,88: activities for improved diabetic wound healing[J]. Eur
104895. Polym J,2022,175:111364.
[11] REAL D A,GAGLIANO A,ORZAN L,et al. Amorphous [23] 徐雨生,廖川江,段美娟. 泊洛沙姆作为温度敏感型凝胶
solid dispersions of triclabendazole:keeping the supersatu‐ 基 质 的 安 全 性 评 价 [J]. 食 品 与 药 品 ,2021,23(4):
rated drug solution using poloxamers[J]. J Drug Deliv Sci 337-341.
Technol,2024,91:105223. XU Y S,LIAO C J,DUAN M J. Safety evaluation of po‐
[12] SAKHI M,KHAN A,KHAN I,et al. Effect of polymeric loxamer as a temperature-sensitive gel matrix[J]. Food
stabilizers on the size and stability of PLGA paclitaxel Drug,2021,23(4):337-341.
nanoparticles[J]. Saudi Pharm J,2023,31(9):101697. [24] TOBIN K V,BROGDEN N K. Thermosensitive biomate‐
[13] MERUVA S,THOOL P,SHAH S,et al. Formulation and rial gels with chemical permeation enhancers for en‐
performance of irbesartan nanocrystalline suspension and hanced microneedle delivery of naltrexone for managing
granulated or bead-layered dried powders:part Ⅰ[J]. Int J opioid and alcohol dependency[J]. Biomater Sci,2023,11
Pharm,2019,568:118189. (17):5846-5858.
[14] MERUVA S,THOOL P,GONG Y C,et al. Role of wet‐ [25] KHAN S,MINHAS M U,SINGH THAKUR R R,et al.
ting agents and disintegrants in development of danazol Microneedles assisted controlled and improved transder‐
nanocrystalline tablets[J]. Int J Pharm,2020,577:119026. mal delivery of high molecular drugs via in situ forming
[15] KARAMI Z,ZANJANI M S,ANDALIB S,et al. In- depot thermoresponsive poloxamers gels in skin micro‐
· 634 · China Pharmacy 2025 Vol. 36 No. 5 中国药房 2025年第36卷第5期